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排序方式: 共有72条查询结果,搜索用时 15 毫秒
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Konstantinov Vsevolod Berdenova Saule Satkangulova Gulnara Reznik Alexander Isralowitz Richard 《International journal of mental health and addiction》2022,20(2):888-894
International Journal of Mental Health and Addiction - 相似文献
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Nabi S. Shabanov Kamil Sh. Rabadanov Sagim I. Suleymanov Akhmed M. Amirov Abdulgalim B. Isaev Dinara S. Sobola Eldar K. Murliev Gulnara A. Asvarova 《Materials》2021,14(9)
The aim of this work is preparation and investigation of copper conductive paths by printing with a different type of functional ink. The solutions based on copper-containing complex compounds were used as inks instead of dispersions of metal nanoparticles. Thermal characteristics of synthesized precursors were studied by thermogravimetry in an argon atmosphere. Based on the comparison of decomposition temperature, the dimethylamine complex of copper formate was found to be more suitable precursor for the formation of copper layers. Structure and performance of this compound was studied in detail by X-ray diffraction, test of wettability, printing on flexible substrate, and electrical measurements. 相似文献
4.
Makhmud M. Aliev Rustam Z. Yuldashev Gulnara S. Adilova Gulnora A. Yusupaileva 《Pediatric surgery international》2014,30(3):295-299
Introduction
Variceal haemorrhage in children with extrahepatic portal hypertension is best controlled by an effective decompressive shunt, but long-term follow up of children who have had splenorenal shunt due to extrahepatic portal hypertension (EHPH) gave evidence for assuming the risk of renal venous hypertension (RVH).Purpose
To study renal hemodynamic before and after portal decompression.Methods
The results of 144 portosystemic shunt operations were followed from 2005 to 2013. Seventy-two patients applied central splenorenal shunt (CSS) with splenectomy, ten side-to-side splenorenal shunt without splenectomy (SRSss), ten patients assessed the distal splenorenal shunt (DSS). Forty-three iliacomesenterial anastomosis (IMA) and in nine cases performed mesocaval anastomosis (MCA). Children had a standard pre- and postoperative work up including gastrointestinal endoscopy, Doppler ultrasonography (US), multi-slice computed tomography (MSCT) and renography.Results
In 11 (15.2 %) patients after CSS on duplex, Doppler study revealed signs of impeded venous outflow on the left renal vein (LRV). At long-term follow-up PI and RI of left renal artery remained at high numbers (1.48 ± 0.17 and 0.72 ± 0.19, p ≤ 0.05, respectively) after the CSS. Venous blood flow in the LRV at the hilum showed slower speed performance in groups of CSS and after IMA. After DSS, these signs have not been detected. Four patients after IMA on US Doppler and CT angiography revealed dilated left testicular and ovarian veins, with retrograde blood flow in them, which clinically manifested as left flank pain, macro- and microhematuria, varicocele and ovaricocele.Conclusion
The study shows that CSS and IMA more negatively effect on hemodynamics of left kidney and symptoms of RVH obviously due to shunting the large amounts of blood from a system of high pressure to a low. 相似文献5.
Borja-Cabrera GP Cruz Mendes A Paraguai de Souza E Hashimoto Okada LY de A Trivellato FA Kawasaki JK Costa AC Reis AB Genaro O Batista LM Palatnik M Palatnik-de-Sousa CB 《Vaccine》2004,22(17-18):2234-2243
The potential effect of the fucose mannose ligand (FML)-vaccine on immunotherapy of canine visceral leishmaniasis was assayed on five mongrel dogs experimentally infected with Leishmania donovani and on 21 Leishmania chagasi naturally infected dogs when seropositive to FML but completely asymptomatic. The clinical signs of the experimentally infected, symptomatic dogs only disappeared after the complete vaccination. Protection was obtained in 3/5 animals that remained asymptomatic, IDR positive and parasite free, 1 year after infection. Furthermore, the asymptomatic, FML-vaccine treated dogs showed stable anti-FML IgG1 levels, increasing IgG2 levels and 79-95% of positive DTH response, during the whole experiment. Twenty-two months after complete vaccination, no obits due to visceral leishmaniasis were recorded and 90% of these dogs were still asymptomatic, healthy and parasite free. On the other hand, 37% (17/46 dogs) kala-azar obits were recorded in a control group that received no treatment during the same period, and that was FML-seropositive and asymtpomatic at the beginning of the assay. Our results indicate that the FML-vaccine was effective in the immunotherapy against visceral leishmaniasis of asymptomatic infected dogs. Normal proportions of CD4 and CD21 lymphocytes were detected in PBMC by FACS analysis, in dogs submitted to immunotherapy, suggesting their non-infectious condition. All animals showed as well significantly increased percents of CD8 lymphocytes as expected for Quillaja saponin (QuilA) vaccine treatments. 相似文献
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Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity 总被引:1,自引:0,他引:1
Bingham A Mamyrova G Rother KI Oral E Cochran E Premkumar A Kleiner D James-Newton L Targoff IN Pandey JP Carrick DM Sebring N O'Hanlon TP Ruiz-Hidalgo M Turner M Gordon LB Laborda J Bauer SR Blackshear PJ Imundo L Miller FW Rider LG;Childhood Myositis Heterogeneity Study Group 《Medicine》2008,87(2):70-86
We describe the clinical features of 28 patients with juvenile dermatomyositis (JDM) and 1 patient with adult-onset dermatomyositis (DM), all of whom developed lipodystrophy (LD) that could be categorized into 1 of 3 phenotypes, generalized, partial, or focal, based on the pattern of fat loss distribution. LD onset was often delayed, beginning a median of 4.6 years after diagnosis of DM. Calcinosis, muscle atrophy, joint contractures, and facial rash were DM disease features found to be associated with LD. Panniculitis was associated with focal lipoatrophy while the anti-p155 autoantibody, a newly described myositis-associated autoantibody, was more associated with generalized LD. Specific LD features such as acanthosis nigricans, hirsutism, fat redistribution, and steatosis/nonalcoholic steatohepatitis were frequent in patients with LD, in a gradient of frequency and severity among the 3 sub-phenotypes. Metabolic studies frequently revealed insulin resistance and hypertriglyceridemia in patients with generalized and partial LD. Regional fat loss from the thighs, with relative sparing of fat loss from the medial thighs, was more frequent in generalized than in partial LD and absent from DM patients without LD. Cytokine polymorphisms, the C3 nephritic factor, insulin receptor antibodies, and lamin mutations did not appear to play a pathogenic role in the development of LD in our patients. LD is an under-recognized sequela of JDM, and certain DM patients with a severe, prolonged clinical course and a high frequency of calcinosis appear to be at greater risk for the development of this complication. High-risk JDM patients should be screened for metabolic abnormalities, which are common in generalized and partial LD and result in much of the LD-associated morbidity. Further study is warranted to investigate the pathogenesis of acquired LD in patients with DM. 相似文献
8.
Juliana Aparecida Najarro Dearo de Morais Ivy Kiemle Trindade-Suedam Maria Teresa Pepato Elcio Marcantonio Jr Ann Wenzel Gulnara Scaf 《Clinical oral implants research》2009,20(8):796-801
Objectives: To evaluate the effect of diabetes mellitus (DM) and insulin therapy on bone density around osseointegrated dental implants by digital subtraction radiography (DSR).
Material and methods: Forty implants were placed in tibiae of 40 adult rats. After a healing period of 2 months, the animals were divided into four groups of 10 animals each: a 2-month control group, sacrificed at time (A), a diabetic group (D), an insulin-treated group (I) and a 4-month control group (C). During 2 months, group I received subcutaneous doses of insulin, whereas groups C and D received only saline. The animals in groups D, I and C were thereafter sacrificed. The glucose plasma levels (GPLs) were monitored throughout the experiment. Film radiographs were taken at implant surgery and on the day of sacrifice. The radiographs were digitized, and bone density in regions of osseointegration (OR) around the implants was evaluated by quantitative DSR between baseline and final images. Differences in shades of gray among the groups were assessed using ANOVA.
Results: GPLs were within normal range for groups A, C and I and higher for group D. There was a significant difference in mean gray shade values in the OR of subtraction images between groups D (122±7) and I (136±5) ( P <0.05) while there were no significant differences between control groups A (128±13) and C (134±10) and the insulin group I.
Conclusions: DM impaired bone density around osseointegrated dental implant. Further, insulin therapy maintained bone density in diabetic rats. 相似文献
Material and methods: Forty implants were placed in tibiae of 40 adult rats. After a healing period of 2 months, the animals were divided into four groups of 10 animals each: a 2-month control group, sacrificed at time (A), a diabetic group (D), an insulin-treated group (I) and a 4-month control group (C). During 2 months, group I received subcutaneous doses of insulin, whereas groups C and D received only saline. The animals in groups D, I and C were thereafter sacrificed. The glucose plasma levels (GPLs) were monitored throughout the experiment. Film radiographs were taken at implant surgery and on the day of sacrifice. The radiographs were digitized, and bone density in regions of osseointegration (OR) around the implants was evaluated by quantitative DSR between baseline and final images. Differences in shades of gray among the groups were assessed using ANOVA.
Results: GPLs were within normal range for groups A, C and I and higher for group D. There was a significant difference in mean gray shade values in the OR of subtraction images between groups D (122±7) and I (136±5) ( P <0.05) while there were no significant differences between control groups A (128±13) and C (134±10) and the insulin group I.
Conclusions: DM impaired bone density around osseointegrated dental implant. Further, insulin therapy maintained bone density in diabetic rats. 相似文献
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