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排序方式: 共有847条查询结果,搜索用时 15 毫秒
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2.
Carel Bron Michel Wensing Jo LM Franssen Rob AB Oostendorp 《BMC musculoskeletal disorders》2007,8(1):107
Background
Shoulder disorders are a common health problem in western societies. Several treatment protocols have been developed for the clinical management of persons with shoulder pain. However available evidence does not support any protocol as being superior over others. Systematic reviews provide some evidence that certain physical therapy interventions (i.e. supervised exercises and mobilisation) are effective in particular shoulder disorders (i.e. rotator cuff disorders, mixed shoulder disorders and adhesive capsulitis), but there is an ongoing need for high quality trials of physical therapy interventions. Usually, physical therapy consists of active exercises intended to strengthen the shoulder muscles as stabilizers of the glenohumeral joint or perform mobilisations to improve restricted mobility of the glenohumeral or adjacent joints (shoulder girdle). It is generally accepted that a-traumatic shoulder problems are the result of impingement of the subacromial structures, such as the bursa or rotator cuff tendons. Myofascial trigger points (MTrPs) in shoulder muscles may also lead to a complex of symptoms that are often seen in patients diagnosed with subacromial impingement or rotator cuff tendinopathy. Little is known about the treatment of MTrPs in patients with shoulder disorders. 相似文献3.
4.
Fixation of Kirschner wires: a comparison between hammering and drilling k-wires into ribs of pigs 总被引:1,自引:1,他引:0
E. B. Wassenaar B. B. G. M. Franssen D. B. van Egmond M. Kon 《European journal of plastic surgery》2006,29(4):153-156
Kirschner wire (K-wire) fixation is a well-accepted method for stabilization of fractures. However, the rotary drill traditionally used for insertion leads to a considerable amount of complications (33%). Another method for insertion was tested which might possibly reduce these complications—hammering. Forty-four K-wires were inserted into the ribs of pigs using a drilling and a hammering technique. Peak extraction force, peak torque, and insertion time were measured. The mean peak extraction forces for drilling and hammering were 57.4 and 129.0 N, respectively. The mean peak torque for drilling and hammering were 2.4 and 5.7e−02 Nm, respectively. Using the drilling technique, it took 73.6 s to insert the K-wire compared with 18.4 s for hammering. At the exit site, there were splinters of bone in 18 of the 22 hammered K-wires and in 2 of the 22 drilled K-wires. This study showed that hammering K-wires into ribs of pigs gives better initial fixation and results in a shorter insertion time.D.B. van Egmond is deceased. 相似文献
5.
Eugénie C.H. van den Ham Jeroen P. Kooman Annemie M.W.J. Schols Fred H.M. Nieman Joan D. Does Frits M.E. Franssen Marco A. Akkermans Paul P. Janssen Johannes P. van Hooff 《American journal of transplantation》2005,5(8):1957-1965
Exercise intolerance is common in hemodialysis (HD) and renal transplant (RTx) patients. Aim of the study was to assess to what extent exercise capacity and skeletal muscle strength of RTx patients differ from HD patients and healthy controls and to elucidate potential determinants of exercise capacity in RTx patients. Exercise capacity, muscle strength, lean body mass (LBM) and physical activity level (PAL) were measured by cycle-ergometry, isokinetic dynamometry, DEXA and Baecke Questionnaire, respectively, in 35 RTx, 16 HD and 21 controls. VO2peak and muscle strength of the RTx patients were significantly lower compared to controls (p<0.01), but not different compared to HD patients. In RTx patients, strength (p<0.001), PAL (p=0.001) and age (p=0.045) were significant predictors of VO2peak. Muscle strength was related to LBM (p=0.001) and age (p=0.001), whereas gender (p<0.001) and renal function (p=0.01) turned out to be significant predictors of LBM. No effects of corticosteroids were observed. Exercise capacity and muscle strength seem equally reduced in RTx and HD patients compared to controls. In RTx patients, muscle strength and PAL are highly related to exercise capacity. Renal function appears to be a significant predictor of LBM, and through the LBM, of muscle strength and exercise capacity. 相似文献
6.
Goddijn Mariette; Joosten Hannie; Knegt Lia; van der Veen Fulco; Franssen Maureen; Bonsel Gouke; Leschot Nico 《Human reproduction (Oxford, England)》2004,19(9):2172
Sir, We thank Mayumi Sugiura-Ogasawara et al. for their commentson our paper (Goddijn et al., 2004 相似文献
7.
Krushkal J; Xiong M; Ferrell R; Sing CF; Turner ST; Boerwinkle E 《Human molecular genetics》1998,7(9):1379-1383
Elevated blood pressure is an important risk factor for renal-, cerebro-
and cardiovascular diseases. We used an efficient discordant sib-pair
ascertainment scheme to investigate the impact of the distal end of the
long arm of human chromosome 5 (chromosomal region 5q31.1-qter) containing
genes for the alpha1B and beta2 adrenergic receptors and the dopamine
receptor type 1A on variation of systolic blood pressure in young
Caucasians. We measured eight highly polymorphic markers spanning this
positional candidate gene-rich region in 427 individuals from 55
three-generation pedigrees containing 69 discordant sibling pairs, and
calculated multipoint identity by descent (MIBD) probabilities. The results
of genetic linkage and association tests indicate that the region between
markers D5S2093 and D5S462 is significantly linked to one or more
polymorphic genes influencing interindividual variation in systolic blood
pressure levels. Since the alpha1B adrenergic receptor and dopamine
receptor type 1A genes are located close to these markers, these data
suggest that genetic variation in one or both of these G protein-coupled
receptors, which participate in the control of vascular tone, plays an
important role in influencing interindividual variation in systolic blood
pressure levels.
相似文献
8.
S G Sclan J R Foster B Reisberg E Franssen J Welkowitz 《Psychiatric journal of the University of Ottawa》1990,15(4):221-226
Conventional psychometric measures uniformly yield zero or near zero scores (i.e., "bottom-out") as patients with Alzheimer's disease (AD) progress to the more severe stages of the illness. Consequently, there are no psychometric measures which objectively assess the mental abilities of AD patients with very severe cognitive impairment. We explored the hypothesis that mental function in AD patients with very severe cognitive impairment can be effectively assessed using test measures developed to assess the earliest stage of cognitive development as proposed by Piaget. We also investigated the relationship between decline on these experimental cognitive measures and progressive functional disability in patients with severe cognitive impairment. The results indicate that modified instruments derived from measures developed to assess Piaget's sensorimotor stage of cognitive development provide useful information about the cognitive abilities of very severely impaired AD patients. These modified instruments provide a measure of cognition in these extremely impaired patients that has acceptable validity and demonstrable reliability. 相似文献
9.
Acute porphyria is rare in orientals. We describe a Chinese woman with recurrent generalised tonic-clonic seizures and abdominal pain. Genomic DNA studies identified a heterozygous base substitution from guanine to adenine at nucleotide position 503, resulting in substitution of arginine by histidine at position 168 of the protein (R168H). This genetic abnormality is similar to the mutation reported in Caucasians with variegate porphyria. To the best of our knowledge, this is the first report in the English literature a Chinese patient with variegate porphyria with an identifiable mutation. A brief review of porphyria is presented. 相似文献
10.
This long-term follow-up study examined patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and only sensory
symptoms at first presentation, with emphasis on the development of motor symptoms and long-term disability. From all CIDP
patients referred to our Department between 1987 and 1995, seven had only sensory symptoms at first clinical presentation.
These were investigated according to a standard protocol, including a quantified clinical neurological examination and nerve
conduction studies. The mean duration of the disease before weakness developed was 3.1 years, but varied considerably (0.8–6.3
years). At follow-up, weakness developed in five patients and persisted in three of them. Five patients were not seriously
incapacitated by their disease (Rankin 1 or 2), four of them being in remission now and one showing a very slow progression
of disease. Two patients were moderately disabled (Rankin 3); one had severe persistent sensory ataxia and only weakness during
relapses and one had stepwise progression and moderate weakness. Motor nerve conduction studies revealed that the most notable
worsening in the entire group of patients was a decrease in distal compound muscle action potential amplitudes, indicating
the development of distal conduction block or axonal degeneration. These findings show that CIDP with only sensory symptoms
is a transient clinical stage that precedes the appearance of weakness in about 70% of patients. The long-term prognosis does
not differ from that of patients with CIDP who have weakness at the beginning of the disease.
Received: 3 December 1998 Received in revised form: 17 May 1999 Accepted: 2 July 1999 相似文献