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Multifocal Malignant Hemangioendothelioma Presenting as Acute Hepatitis A Clinicopathologic Study 总被引：2，自引：0，他引：2
AVRUM M. STEIN D.O. KARIM FAWAZ M.D. ALIREZA TABHIZI M.D. RITA BLANCHARD M.D. SUSAN HOU M.D. 《The American journal of gastroenterology》1977,67(4):370-374
A patient with malignant hemangioendothelioma of the liver is described. The patient's clinical presentation and course were that of fulminant hepatic necrosis. Complications included upper gastrointestinal hemorrhage, hepatic encephalopathy, abnormal coagulation parameters and the hepatorenal syndrome. The duration of the illness from the onset of symptoms to its fatal outcome was five weeks. 相似文献
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NWORA LANCE OKEKE FAWAZ ALENEZI GERALD S. BLOOMFIELD ALLISON DUNNING MEREDITH E. CLEMENT SVATI H. SHAH SUSANNA NAGGIE ERIC J. VELAZQUEZ 《Journal of cardiac failure》2018,24(8):496-503
Objective
The aim of this work was to investigate determinants of structural myocardial abnormalities in persons living with human immunodeficiency virus (PLWH).Methods and Results
We reviewed archived transthoracic echocardiograms (TTEs) performed on PLWH at Duke University Medical Center from 2001 to 2012. The primary outcomes were presence of left ventricular hypertrophy (LVH) or diastolic dysfunction (DD). TTEs for 498 human immunodeficiency virus–infected persons were reviewed (median age 44 years, 38% female, 72% black, 34% with hypertension, 15% with diabetes). Among those with usable images, LVH was detected in 174 of 473 persons (37%) according to LV mass criteria and in 99 of 322 persons (31%) according to American Society of Echocardiography LV mass index criteria. Definite DD was detected in 18 of 224 persons (8%). LVH was more common in PLWH with a CD4 count ≤ 200 cells/mm3 proximal to TTE (adjusted OR 1.68, 95% CI 1.08–2.62), CD4 nadir ≤ 200 cells/mm3 (adjusted OR 1.63, 95% CI 1.04–2.54) and less common in persons with viral suppression (OR 0.46, 95% CI 0.27–0.80). Lower CD4 nadirs (P?=?.002) and proximal CD4 counts (P?=?.002) were also associated with DD.Conclusions
Persons with a history of advanced human immunodeficiency virus–associated immune suppression are at higher risk of LVH and DD than infected persons with preserved immune function. 相似文献3.
C. DUPLÀA T. COUFFINHAL L. LABAT J. FAWAZ C. MOREAU I. BTETZ J. BONNET 《European journal of clinical investigation》1993,23(8):474-479
Abstract. Monocyte adhesion to endothelium appearing determinant in atherosclerosis, the possibility that circulating monocytes have an increase of their adherence on endothelial cells were investigated in patients with atherosclerosis. The adherence of circulating monocytes on endothelial cell monolayers was determined in 26 patients with atherosclerosis (age 59 ± 4), and 25 healthy individuals (age 55 ± 4). No difference of monocyte adherence was observed between the two groups (18.8±13.8% vs 19.2±13.4%), or following atherosclerosis severity. However monocyte adherence appeared positively correlated to smoking habits (r = 0–34, P<0.02) and fibrinogen level (r = 0.31, P<0.03), and negatively to the degree of plasmatic LDL oxidation (r=-0.28, P<0.05 ). These results suggest that the adherence of monocytes to endothelial cells is not increased in atherosclerosis, but enhanced by risk factors. A weak plasmatic LDL oxydation could inhibit monocyte adhesion. 相似文献
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KARIM A. FAWAZ M.D. STFPHEN M. BLOOM M.D. CONSTANTINK A. PAPPAS M.D. JOHN M. KELLUM JR. M.D. 《The American journal of gastroenterology》1980,73(3):265-270
A 71-year old woman initially presented with abdominal pain and an x-ray picture of ischemia of the terminal ileum. The ischemic changes were transient and reversed spontaneously. Six months later, she presented with the same complaint and an x-ray picture of ileocolic intussusception. At operation, a lipomaof the ileum was the leading point of the intussusception and ischemic changes of the ileum were evident. 相似文献
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