全文获取类型
收费全文 | 1952篇 |
免费 | 299篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 108篇 |
妇产科学 | 25篇 |
基础医学 | 121篇 |
口腔科学 | 27篇 |
临床医学 | 293篇 |
内科学 | 703篇 |
皮肤病学 | 62篇 |
神经病学 | 187篇 |
特种医学 | 279篇 |
外科学 | 201篇 |
综合类 | 35篇 |
预防医学 | 95篇 |
眼科学 | 18篇 |
药学 | 60篇 |
中国医学 | 2篇 |
肿瘤学 | 61篇 |
出版年
2023年 | 52篇 |
2022年 | 16篇 |
2021年 | 30篇 |
2020年 | 92篇 |
2019年 | 20篇 |
2018年 | 94篇 |
2017年 | 71篇 |
2016年 | 73篇 |
2015年 | 63篇 |
2014年 | 104篇 |
2013年 | 115篇 |
2012年 | 59篇 |
2011年 | 54篇 |
2010年 | 86篇 |
2009年 | 113篇 |
2008年 | 53篇 |
2007年 | 50篇 |
2006年 | 53篇 |
2005年 | 33篇 |
2004年 | 27篇 |
2003年 | 27篇 |
2002年 | 24篇 |
2001年 | 40篇 |
2000年 | 19篇 |
1999年 | 29篇 |
1998年 | 81篇 |
1997年 | 95篇 |
1996年 | 78篇 |
1995年 | 72篇 |
1994年 | 53篇 |
1993年 | 52篇 |
1992年 | 28篇 |
1991年 | 16篇 |
1990年 | 28篇 |
1989年 | 55篇 |
1988年 | 45篇 |
1987年 | 27篇 |
1986年 | 21篇 |
1985年 | 20篇 |
1984年 | 16篇 |
1982年 | 15篇 |
1981年 | 16篇 |
1980年 | 14篇 |
1978年 | 9篇 |
1977年 | 10篇 |
1976年 | 11篇 |
1975年 | 10篇 |
1972年 | 12篇 |
1971年 | 12篇 |
1969年 | 13篇 |
排序方式: 共有2291条查询结果,搜索用时 0 毫秒
1.
2.
3.
4.
B Bonet M Viana I Sánchez-Vera A Quintanar J Martínez M Espino 《Diabetic medicine》2007,24(11):1192-1198
AIMS: The aims of our study were to determine if insulin resistance is associated with increased plasma levels of non-esterified fatty acids (NEFA), glycerol, 3-hydroxybutyrate and triglycerides in obese children. We also studied whether the presence of acanthosis nigricans (AN) led to further alterations in the above parameters. METHODS: A total of 101 children were studied on their first visit to the paediatric endocrine clinic. Seventy-four were obese, 30 of them with AN. The remaining 27 were non-obese healthy children (control group). NEFAs, glycerol, triglycerides, 3-hydroxybutyrate, insulin, leptin, adiponectin and glucose were determined in blood samples obtained after overnight fasting. The insulin resistance index (IRI) was calculated following the homeostasis model assessment (HOMA). Data from the three groups were compared using appropriate statistical tests. RESULTS: No differences in age, sex ratio and pubertal stage were observed among the three groups. The group of children with the highest body mass index (BMI) showed higher plasma levels of insulin and leptin, higher IRI and lower plasma levels of adiponectin. As insulin and IRI increased, NEFA and 3-hydroxybutyrate decreased and triglycerides increased. When obese children were categorized by BMI, the presence of AN further exacerbated these differences. CONCLUSIONS: In obese children, insulin resistance is associated with plasma lipid alterations suggestive of both decreased adipose tissue lipolysis and hepatic beta-oxidation and increased hepatic synthesis of triglycerides. Such a metabolic condition may facilitate fat storage and hinder weight loss. 相似文献
5.
6.
7.
8.
Ralls PW; Johnson MB; Kanel G; Dobalian DM; Colletti PM; Boswell WD Jr; Radin DR; Halls JM 《Radiology》1986,161(2):451-454
FM sonography - a signal-processing technique that uses frequency and phase information as well as amplitude data - shows promise in evaluation of patients with diffuse liver disease. In a prospective blinded review of 37 patients with biopsy-proved liver disease and 42 healthy volunteers, FM sonography was clearly superior to traditional amplitude-based (AM) sonography in distinguishing healthy from diseased subjects. Statistically significant differences were seen in accuracy (FM, 98.7%; AM, 84.8%), sensitivity (FM, 97.3%; AM, 70.3%), and negative predictive value (FM, 97.7%; AM, 78.8%). Our data also suggest that current FM sonographic techniques cannot differentiate among histologic findings associated with different hepatic parenchymal abnormalities. It is unclear, therefore, whether FM imaging can reduce the numbers of patients who require biopsy for diagnosis or the frequency of biopsy procedures in patients with known disease. 相似文献
9.
10.