全文获取类型
收费全文 | 3399篇 |
免费 | 195篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 96篇 |
儿科学 | 48篇 |
妇产科学 | 106篇 |
基础医学 | 447篇 |
口腔科学 | 32篇 |
临床医学 | 320篇 |
内科学 | 808篇 |
皮肤病学 | 63篇 |
神经病学 | 372篇 |
特种医学 | 45篇 |
外科学 | 236篇 |
综合类 | 11篇 |
一般理论 | 1篇 |
预防医学 | 314篇 |
眼科学 | 84篇 |
药学 | 428篇 |
中国医学 | 9篇 |
肿瘤学 | 195篇 |
出版年
2024年 | 5篇 |
2023年 | 30篇 |
2022年 | 78篇 |
2021年 | 117篇 |
2020年 | 80篇 |
2019年 | 97篇 |
2018年 | 96篇 |
2017年 | 90篇 |
2016年 | 76篇 |
2015年 | 94篇 |
2014年 | 151篇 |
2013年 | 161篇 |
2012年 | 234篇 |
2011年 | 266篇 |
2010年 | 121篇 |
2009年 | 121篇 |
2008年 | 179篇 |
2007年 | 209篇 |
2006年 | 209篇 |
2005年 | 227篇 |
2004年 | 234篇 |
2003年 | 249篇 |
2002年 | 202篇 |
2001年 | 18篇 |
2000年 | 15篇 |
1999年 | 14篇 |
1998年 | 26篇 |
1997年 | 19篇 |
1996年 | 9篇 |
1995年 | 20篇 |
1994年 | 8篇 |
1993年 | 8篇 |
1992年 | 10篇 |
1991年 | 10篇 |
1990年 | 7篇 |
1989年 | 6篇 |
1987年 | 18篇 |
1986年 | 6篇 |
1985年 | 4篇 |
1984年 | 5篇 |
1982年 | 13篇 |
1981年 | 8篇 |
1980年 | 6篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1975年 | 7篇 |
1974年 | 9篇 |
1972年 | 4篇 |
1966年 | 4篇 |
排序方式: 共有3615条查询结果,搜索用时 31 毫秒
1.
2.
3.
4.
5.
6.
7.
Cristina Tassorelli Francesca Mancini Laura Balloni Claudio Pacchetti Giorgio Sandrini Giuseppe Nappi Emilia Martignoni 《Movement disorders》2006,21(12):2240-2243
Currently, the best treatment option for idiopathic cervical dystonia (ICD) is injection of botulinum toxin (BTX) into the affected muscles, whereas rehabilitative approaches have given disappointing results. We evaluated whether the association of an ad hoc rehabilitative program may improve the clinical efficacy of BTX treatment in a single-center, cross-over, controlled study. Forty patients with ICD were randomly assigned to two different treatment groups: (1) BTX type A (BTX-A) plus a specific program of physical therapy (BTX-PT) or (2) BTX-A alone (BTX-0). Patients in the BTX-PT group showed a longer duration of the clinical benefit (118.8 vs. 99.1 days) and needed a lower dose of BTX at reinjection (284.5 vs. 325.5 units). In addition, they showed more marked reductions in their disability in activities of daily living (-9.7 vs. -4.85 points) and subjective pain (-13.35 vs. 6.95 points) scores. Association of BTX-A therapy with a specific program of physical therapy may improve ICD treatment outcome. 相似文献
8.
9.
Support vector machines (SVMs) are a powerful technique developed in the last decade to effectively tackle classification and regression problems. In this paper we describe how support vector machines and artificial neural networks can be integrated in order to classify objects correctly. This technique has been successfully applied to the problem of determining the quality of tiles. Using an optical reader system, some features are automatically extracted, then a subset of the features is determined and the tiles are classified based on this subset. 相似文献
10.
Marek Andrzej Deja Krzysztof S Go?ba Marcin Malinowski Stanis?aw Wo? Maciej Kolowca Jolanta Biernat Maciej Kajor Tomasz J Spyt 《European journal of cardio-thoracic surgery》2005,28(4):551-557
OBJECTIVE: The studies showing the superior characteristics of ITA graft and its impact on the clinical results of coronary artery surgery were performed with ITA harvested almost exclusively as a pedicle. This study assesses the impact of ITA skeletonization on its innervation and reactivity. METHODS: Segments of skeletonized and non-skeletonized ITA were stained with antibodies against protein S-100 to look for the presence of sympathetic nerve fibers. The functional studies were performed on segments of discarded human pedicled ITA that were divided into two 3mm rings, one skeletonized and another non-skeletonized. We compared concentration-effect relationships for the contraction to norepinephrine and endothelium-dependent relaxation to acetylcholine and bradykinin, as well as endothelium-independent relaxation to sodium nitroprusside in skeletonized and non-skeletonized segments of the same ITA. RESULTS: Skeletonized ITA was devoid of protein S-100 positive nerve fibers. It contracted stronger (maximal response 37.0+/-2.04 vs. 25.4+/-1.83mN (P<0.001)) and was twice as sensitive to norepinephrine: pD(2) 6.03+/-0.10 vs. 5.70+/-0.12 (P=0.035). The endothelium-dependent relaxation responses did not differ between skeletonized and non-skeletonized ITA rings. The skeletonized ITA rings appeared over 10 times more sensitive to sodium nitroprusside: pD(2) 6.66+/-0.20 vs. 5.59+/-0.37 (P=0.012)-potency ratio 11.61. The maximal responses did not differ significantly: 112.0+/-6.71 vs. 129.4+/-16.4% (P=0.33). CONCLUSIONS: Skeletonization results in sympathectomy of ITA. It has no effect on endothelium-dependent relaxation but increases reactivity of ITA to norepinephrine. This augmented response to alpha-agonist is small, in comparison with over a ten-fold increase in sensitivity to sodium nitroprusside. Pedicled and skeletonized ITA are functionally significantly different vessels when studied in vitro. 相似文献