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Quality of life was assessed 46 months after an acutemyocardial infarction in a randomized double-blind study ofenalapril versus placebo. Quality of life was evaluated usingthe Nottingham Health Profile (NHP), the Physical Symptoms DistressIndex (PSDI), the Work Performance Scale (WPS) and the LifeSatisfaction Index (LSI). The study comprised 36 women (aged4685 years, mean 68) and 96 males (aged 3981 years,mean 62). Quality of life did not differ significantly between patientstreated with enalapril versus placebo. The scores were (enalaprilvs placebo, mean± SE): average NHP 15.4 ± 2.3vs 17.1 ± 2.3; PSDI 9.5± 1.0 vs 10.8 ±0.9; WPS 19.8 ± 2.0 vs 19.4 ± 1.4; LSI 24.1 ±1.0 vs 22.5 ±1.4. Men reported a better quality of lifethan women on most assessments, and non-smokers and ex-smokersbetter than smokers. Patients with moderate or severe anginapectoris had a worse quality of life measured by PSDI and NHPthan patients with minimal or no angina pectoris. Patients withcongestive heart failure had a higher PSDI than those without(13.6 ± 1.7 vs 9.4 ± 0.7, P<0.05), while nosignificant differences were observed in the NHP scores. In conclusion, quality of life was similar in enalapril andplacebo- treated patients after an acute myocardial infarction.However, it was reduced in patients with angina pectoris orheart failure and in those who continued smoking. 相似文献
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Tuva Kolstad HERTZBERG Karin Isaksson R? Per J?rgen Wiggen VAGLUM Torbj?rn MOUM Jan Ole R?VIK Tore GUDE ?ivind EKEBERG Reidar TYSSEN 《Industrial health》2016,54(2):139-148
The importance of work-home interface stress can vary throughout a medical
career and between genders. We studied changes in work-home interface stress over 5 yr,
and their prediction of emotional exhaustion (main dimension of burn-out), controlled for
other variables. A nationwide doctor cohort (NORDOC; n=293) completed questionnaires at 10
and 15 yr after graduation. Changes over the period were examined and predictors of
emotional exhaustion analyzed using linear regression. Levels of work-home interface
stress declined, whereas emotional exhaustion stayed on the same level. Lack of reduction
in work-home interface stress was an independent predictor of emotional exhaustion in year
15 (β=−0.21, p=0.001). Additional independent predictors
were reduction in support from colleagues (β=0.11, p=0.04)
and emotional exhaustion at baseline (β=0.62, p<0.001).
Collegial support was a more important predictor for men than for women. In separate
analyses, significant adjusted predictors were lack of reduction in work-home interface
stress among women, and reduction of collegial support and lack of reduction in working
hours among men. Thus, change in work-home interface stress is a key independent predictor
of emotional exhaustion among doctors 15 yr after graduation. Some gender differences in
predictors of emotional exhaustion were found. 相似文献
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