全文获取类型
收费全文 | 173273篇 |
免费 | 3483篇 |
国内免费 | 195篇 |
专业分类
耳鼻咽喉 | 4827篇 |
儿科学 | 5613篇 |
妇产科学 | 6646篇 |
基础医学 | 30579篇 |
口腔科学 | 6231篇 |
临床医学 | 9042篇 |
内科学 | 35787篇 |
皮肤病学 | 6993篇 |
神经病学 | 12137篇 |
特种医学 | 6556篇 |
外国民族医学 | 1篇 |
外科学 | 25999篇 |
综合类 | 872篇 |
一般理论 | 11篇 |
预防医学 | 8502篇 |
眼科学 | 5968篇 |
药学 | 6955篇 |
中国医学 | 357篇 |
肿瘤学 | 3875篇 |
出版年
2021年 | 1326篇 |
2019年 | 1115篇 |
2018年 | 1403篇 |
2016年 | 1172篇 |
2015年 | 4448篇 |
2014年 | 5414篇 |
2013年 | 6881篇 |
2012年 | 6445篇 |
2011年 | 6466篇 |
2010年 | 5464篇 |
2009年 | 5183篇 |
2008年 | 5839篇 |
2007年 | 5618篇 |
2006年 | 5934篇 |
2005年 | 5126篇 |
2004年 | 4673篇 |
2003年 | 2961篇 |
2002年 | 1525篇 |
2001年 | 1459篇 |
2000年 | 1513篇 |
1999年 | 1509篇 |
1998年 | 1409篇 |
1997年 | 1379篇 |
1996年 | 1755篇 |
1995年 | 1919篇 |
1994年 | 1924篇 |
1993年 | 1803篇 |
1992年 | 2093篇 |
1991年 | 1820篇 |
1990年 | 1644篇 |
1989年 | 1483篇 |
1988年 | 1350篇 |
1987年 | 1371篇 |
1986年 | 1314篇 |
1985年 | 1127篇 |
1984年 | 1214篇 |
1982年 | 1151篇 |
1978年 | 1228篇 |
1933年 | 1493篇 |
1932年 | 1485篇 |
1931年 | 1475篇 |
1930年 | 1652篇 |
1929年 | 1389篇 |
1928年 | 1531篇 |
1927年 | 1497篇 |
1926年 | 1583篇 |
1925年 | 1544篇 |
1924年 | 1611篇 |
1923年 | 1465篇 |
1922年 | 1442篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Rizzo Manglio Miguel Bluthgen Mara Virginia Recondo Gonzalo Naveira Martin Perfetti Aldo Rizzi Florencia Kuzminin Alejandro Faura Victoria Cerini Matas Videla Alejandro Silva Carlos Lupinacci Lorena Minatta Nicols 《International journal of clinical oncology / Japan Society of Clinical Oncology》2021,26(6):1057-1064
International Journal of Clinical Oncology - Immune-checkpoint inhibitors (ICIs) are standard treatments for metastatic non-small cell lung cancer (NSCLC). Patients with poor performance status... 相似文献
2.
Adjuvant irradiation is the standard treatment after breast conservative surgery. Normofractionated regimen with an overall treatment time of 5 to 6 weeks is often considered as a limiting factor for irradiation compliance. In order to answer this issue, moderate and more recently extreme hypofractionated protocols appeared. We report here oncological outcomes and toxicity of hypofractionated breast irradiation. After defining the frame of moderate and extreme hypofractionated breast irradiations based on overall treatment time, patient selection criteria were listed. According to their levels of proof, the results of moderate and extreme hypofractionated breast irradiation were analysed. Overall treatment time for moderate hypofractionated breast irradiation ranged from 3 to 4 weeks, while for extreme hypofractionated breast irradiation, it was less than 1 week. For moderate hypofractionated breast irradiation, whole breast irradiation was currently performed with or without lymph node irradiation. Moderate hypofractionated breast irradiation has proven to be as safe and as efficient as normofractionated breast irradiation with level IA evidence. For extreme hypofractionated breast irradiation, phase III randomized trials confirmed that accelerated partial breast irradiation was non-inferior in terms of local control compared to normofractionated whole breast irradiation (with external beam radiation therapy and multicatheter brachytherapy), with similar acute and late toxicity. While the use of intraoperative breast irradiation remains under debate, new very accelerated partial breast irradiation (overall treatment time not exceeding 2 days) protocols emerged with encouraging results. Accelerated partial breast irradiation is warranted for extreme hypofractionated breast irradiation and is indicated for low-risk breast cancers. Moderate and extreme hypofractionated breast irradiation regimens are validated and can be routinely proposed according to patient selection criteria. 相似文献
3.
4.
5.
Selwyn Arlington Headley Nayara Emily Viana Mariana de Mello Zanim Michelazzo Ana Aparecida Correa Xavier Cícero Júlio Silva Costa Felipe Hideki Ogo de Pinho Marcelo Diniz dos Santos 《Transboundary and Emerging Diseases》2020,67(Z2):49-59
Neorickettsia helminthoeca (NH), the agent of salmon poisoning disease or canine neorickettiosis (CN), is a bacterial endosymbiont of the nematode Nanophyetus salmincola, and infections are spreading among specific fish‐eating mammalians. This article describes the pathologic and immunohistochemical findings associated with spontaneous NH‐induced infections in dogs from Southern Brazil. The principal pathologic findings were hypertrophy of Peyer patches and lymphadenopathy with lymphocytic proliferation, chronic interstitial pneumonia, and chronic enteritis associated with positive intralesional immunoreactivity to antigens of NH within macrophages and histiocytes. Positive immunoreactivity against canine parvovirus‐2 (CPV‐2) or/and canine distemper virus was not detected in the evaluated intestinal segments or in the samples from the cerebellum and lungs, respectively, from the dogs evaluated. These findings demonstrated that NH was involved in the enteric, pulmonary, and lymphoid lesions herein described, and provide additional information to confirm the occurrence of this bacterial endosymbiont within this geographical location. It is proposed that chronic pneumonia should be considered as a pathologic manifestation of NH‐induced infections. Additionally, our results show that the occurrences of CN seem to be underdiagnosed in Southern Brazil due to the confusion with the incidence of CPV‐2. 相似文献
6.
7.
Well‐being,health and fitness of children who use wheelchairs: Feasibility study protocol to develop child‐centred ‘keep‐fit’ exercise interventions 下载免费PDF全文
8.
9.
10.