全文获取类型
收费全文 | 1537篇 |
免费 | 100篇 |
国内免费 | 30篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 69篇 |
妇产科学 | 41篇 |
基础医学 | 147篇 |
口腔科学 | 67篇 |
临床医学 | 191篇 |
内科学 | 288篇 |
皮肤病学 | 41篇 |
神经病学 | 30篇 |
特种医学 | 278篇 |
外科学 | 170篇 |
综合类 | 60篇 |
一般理论 | 4篇 |
预防医学 | 104篇 |
眼科学 | 16篇 |
药学 | 97篇 |
肿瘤学 | 52篇 |
出版年
2018年 | 16篇 |
2017年 | 11篇 |
2016年 | 9篇 |
2015年 | 18篇 |
2014年 | 17篇 |
2013年 | 18篇 |
2011年 | 13篇 |
2010年 | 41篇 |
2009年 | 28篇 |
2008年 | 10篇 |
2007年 | 28篇 |
2006年 | 21篇 |
2005年 | 14篇 |
2004年 | 10篇 |
2003年 | 19篇 |
2002年 | 12篇 |
2001年 | 18篇 |
2000年 | 11篇 |
1999年 | 21篇 |
1998年 | 73篇 |
1997年 | 96篇 |
1996年 | 104篇 |
1995年 | 62篇 |
1994年 | 55篇 |
1993年 | 64篇 |
1992年 | 26篇 |
1991年 | 20篇 |
1990年 | 38篇 |
1989年 | 55篇 |
1988年 | 54篇 |
1987年 | 46篇 |
1986年 | 36篇 |
1985年 | 45篇 |
1984年 | 22篇 |
1983年 | 20篇 |
1982年 | 22篇 |
1981年 | 20篇 |
1980年 | 20篇 |
1979年 | 14篇 |
1978年 | 11篇 |
1977年 | 20篇 |
1976年 | 16篇 |
1959年 | 30篇 |
1958年 | 53篇 |
1957年 | 41篇 |
1956年 | 49篇 |
1955年 | 45篇 |
1954年 | 33篇 |
1949年 | 30篇 |
1948年 | 37篇 |
排序方式: 共有1667条查询结果,搜索用时 78 毫秒
1.
Isolated patellofemoral arthritis is an increasingly recognized entity, and is usually associated with previous patellofemoral dysplasia or instability. Patellofemoral arthroplasty (PFA) has evolved significantly in recent years, both in terms of implant design and importantly in the understanding of appropriate patient selection. This review outlines the indications and investigations for PFA, provides a brief history of the development of contemporary implants, and presents the clinical outcomes for the prostheses most commonly used in the UK. In addition, it provides a detailed surgical technique for implantation of an onlay implant, with tips on how to optimize patellofemoral biomechanics and thus achieve a consistently good outcome. 相似文献
2.
3.
Sonoelasticity imaging of prostate cancer: in vitro results 总被引:2,自引:0,他引:2
4.
5.
6.
7.
8.
9.
Ten thrombocytopenic patients (platelets < 10–24 × 10(9)/L) who were refractory to platelet transfusion were investigated for their responsiveness to staphylococcal protein A column therapy. Nine patients had previously been treated with steroids, intravenous immune globulin, and/or other forms of immunosuppressive therapy without improvement in their transfusion response. All patients were receiving multiple platelet transfusions without achieving 1-hour corrected count increments (CCIs) > or = 7500. Eight patients had antibodies that reacted with platelets and were directed against HLA class I antigens, ABO antigens, and/or platelet-specific alloantigens. Plasma (500-2000 mL) from each patient was passed over a protein A silica gel column and then returned to the patient. Patients received from 1 to 14 treatments. A positive response to protein A therapy was defined as at least a doubling of the pretreatment platelet count and/or two successive 10- to 120-minute posttransfusion CCIs > or = 7500. Following plasma treatments, 6 of 10 patients responded with daily platelet counts that averaged 48 +/− 11 × 10(9) per L as compared with counts of 16 +/− 7 × 10(9) per L (p < 0.0005) before treatment. Posttransfusion CCI values determined in four of these patients averaged 2480 +/− 810 and 10,010 +/− 3540 (p < 0.005) before and after treatment, respectively. In contrast, among the four unresponsive patients, platelet counts averaged 10 +/− 9 and 13 +/− 10 × 10(9) per L (p = NS), respectively, while posttransfusion CCIs were 700 +/− 1410 and 1520 +/− 2460 (p = NS), respectively.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
10.
Andrew BOFINGER Justin WESTHUYZEN David SALTISSI Colleen MORGAN Helen HEALY 《Nephrology (Carlton, Vic.)》1997,3(2):169-177
Summary: Uraemic dyslipidaemia is a major risk factor for cardiovascular disease in end-stage renal failure patients. In patients without renal failure, high levels and qualitative abnormalities of low-density lipoprotein (LDL) are known to be atherogenic. Recently, LDL subfraction analysis has associated premature coronary artery disease with a high prevalence of small, dense LDL particles characterizing the LDL subclass phenotype B. We therefore examined the lipid profiles, LDL subfraction distribution and phenotypes in our population of haemodialysis (HD; n = 30) and peritoneal dialysis patients (PD; n = 17), and compared them to 40 asymptomatic, non-uraemic volunteers. Dialysis patients had significantly higher triglyceride and VLDL cholesterol concentrations and lower HDL cholesterol and smaller LDL peak particle diameters. PD patients had significantly higher total cholesterol, glycated haemoglobin and fasting blood glucose levels with smaller LDL peak particle diameters (24.4 [0.1] vs 24.8 [0.1 nm] than HD. Both groups showed significant negative correlations between plasma triglyceride and LDL peak particle diameter, and positive correlations between HDL cholesterol and LDL peak particle diameter. All the PD patients expressed the B phenotype (LDL peak diameter ± 25.5 nm) compared to 73% of HD patients. This study demonstrates that HD and especially PD patients have atherogenic lipid profiles which are associated with a predominance of small dense LDL particles and the highly atherogenic LDL subclass phenotype B. 相似文献