全文获取类型
收费全文 | 1603篇 |
免费 | 147篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 83篇 |
妇产科学 | 33篇 |
基础医学 | 124篇 |
口腔科学 | 44篇 |
临床医学 | 180篇 |
内科学 | 345篇 |
皮肤病学 | 29篇 |
神经病学 | 74篇 |
特种医学 | 293篇 |
外科学 | 215篇 |
综合类 | 58篇 |
一般理论 | 1篇 |
预防医学 | 94篇 |
眼科学 | 57篇 |
药学 | 55篇 |
中国医学 | 1篇 |
肿瘤学 | 59篇 |
出版年
2021年 | 10篇 |
2018年 | 22篇 |
2017年 | 16篇 |
2016年 | 16篇 |
2015年 | 24篇 |
2014年 | 24篇 |
2013年 | 27篇 |
2012年 | 40篇 |
2011年 | 36篇 |
2010年 | 47篇 |
2009年 | 50篇 |
2008年 | 42篇 |
2007年 | 42篇 |
2006年 | 47篇 |
2005年 | 35篇 |
2004年 | 28篇 |
2003年 | 42篇 |
2002年 | 27篇 |
2001年 | 23篇 |
2000年 | 27篇 |
1999年 | 30篇 |
1998年 | 57篇 |
1997年 | 74篇 |
1996年 | 62篇 |
1995年 | 45篇 |
1994年 | 56篇 |
1993年 | 56篇 |
1992年 | 35篇 |
1991年 | 22篇 |
1990年 | 18篇 |
1989年 | 55篇 |
1988年 | 71篇 |
1987年 | 52篇 |
1986年 | 61篇 |
1985年 | 40篇 |
1984年 | 30篇 |
1983年 | 41篇 |
1982年 | 25篇 |
1981年 | 25篇 |
1980年 | 29篇 |
1979年 | 21篇 |
1978年 | 26篇 |
1977年 | 20篇 |
1976年 | 24篇 |
1975年 | 27篇 |
1974年 | 14篇 |
1973年 | 11篇 |
1972年 | 14篇 |
1971年 | 19篇 |
1967年 | 7篇 |
排序方式: 共有1753条查询结果,搜索用时 0 毫秒
1.
2.
David Hirschwerk Christine C Ginocchio Maureen Bythrow Susan Condon 《Infection control and hospital epidemiology》2006,27(3):315-317
We cared for a patient with methicillin-resistant Staphylococcus aureus bacteremia who experienced clinical failure with daptomycin. The failure was accompanied by progressive elevation of the daptomycin minimum inhibitory concentration during treatment. DNA fingerprinting confirmed that the minimum inhibitory concentration elevation occurred within the same strain of methicillin-resistant Staphylococcus aureus. This observation provides important new information to clinicians who adopt this promising drug for treatment of serious infections caused by methicillin-resistant Staphylococcus aureus. 相似文献
3.
Preliminary evidence for a role of apolipoprotein E alleles in identifying haemodialysis patients at high vascular risk 总被引:1,自引:0,他引:1
Olmer M; Renucci JE; Planells R; Bouchouareb D; Purgus R 《Nephrology, dialysis, transplantation》1997,12(4):691-693
Conventional risk factors have very low predictive power in identifying
haemodialysis patients at high risk of vascular accidents. A role for
apolipoprotein E isotypes was looked for in a small, but rigorously
defined, cohort of longterm haemodialysis patients. In individuals with
high vascular risk, as identified by higher common carotid intima/media
thickness, we found an excess of apolipoprotein E4 alleles. This
preliminary result requires confirmation in large patient cohorts.
相似文献
4.
5.
6.
7.
8.
9.
Hodgkin disease: CT of the thymus 总被引:2,自引:0,他引:2
The computed tomography (CT) scans in two groups of patients with Hodgkin disease were reviewed to determine the frequency of thymic enlargement. In 50 CT scans from 50 patients with evidence of thoracic disease on CT scans who were examined for primary staging, the thymus was enlarged in 15 of 50 (30%). Fifty CT scans were obtained from 44 patients at the time of 50 separate episodes of known or suspected relapse. Relapse occurred in the mediastinum in 12 episodes, lung parenchyma in five, and both sites in one. Thymic enlargement thought to be due to involvement by disease was present in seven of 18 (38%). Mediastinal disease was associated with thymic enlargement in all but one patient in whom a thymic cyst developed after radiation therapy. Differentiation of thymic enlargement from enlarged superior mediastinal lymph nodes was easily made in all but two patients. Thymic enlargement in the absence of lymph node enlargement may indicate a different disease, since isolated Hodgkin disease of the thymus is uncommon. Primary thymic tumor should be considered initially, whereas after treatment, rebound hyperplasia of the thymus may be the cause of enlargement. 相似文献
10.
Use of restriction fragment length polymorphisms resolved by pulsed-field gel electrophoresis for subspecies identification of mycobacteria in the Mycobacterium avium complex and for isolation of DNA probes. 下载免费PDF全文
J W Coffin C Condon C A Compston K N Potter L R Lamontagne J Shafiq D Y Kunimoto 《Journal of clinical microbiology》1992,30(7):1829-1836
Mycobacterial strains from the Mycobacterium avium complex were compared with each other and with Mycobacterium phlei isolates by restriction endonuclease digestion of chromosomal DNA with SspI and analysis by pulsed-field gel electrophoresis. Characteristic profiles were observed for known typed strains, and five groups were identified. Primary bovine isolates identified as Mycobacterium paratuberculosis by classical methods were shown to fall into both the M. paratuberculosis- and M. avium-like groups. M. paratuberculosis 18 was in the latter category. Two Mycobacterium intracellulare strains of different Schaefer serotypes had different digestion profiles. In addition, this system was exploited for the preparation of DNA probes by the isolation, digestion, and subcloning of DNA fragments separated by pulsed-field gel electrophoresis. Probe JC12 hybridized only to M. avium complex strains, but not to M. phlei, showing characteristic hybridization profiles for each of the groups previously identified by pulsed-field gel electrophoresis. The approach taken in the study lends itself to the comparative analysis of members of the M. avium complex and to the isolation and characterization of DNA probes with specificity for these mycobacteria. 相似文献