全文获取类型
收费全文 | 16218篇 |
免费 | 1313篇 |
国内免费 | 501篇 |
专业分类
耳鼻咽喉 | 172篇 |
儿科学 | 303篇 |
妇产科学 | 383篇 |
基础医学 | 2127篇 |
口腔科学 | 339篇 |
临床医学 | 1882篇 |
内科学 | 2927篇 |
皮肤病学 | 321篇 |
神经病学 | 1086篇 |
特种医学 | 715篇 |
外国民族医学 | 3篇 |
外科学 | 1957篇 |
综合类 | 1160篇 |
一般理论 | 2篇 |
预防医学 | 1039篇 |
眼科学 | 457篇 |
药学 | 1411篇 |
4篇 | |
中国医学 | 336篇 |
肿瘤学 | 1408篇 |
出版年
2024年 | 30篇 |
2023年 | 170篇 |
2022年 | 419篇 |
2021年 | 597篇 |
2020年 | 321篇 |
2019年 | 431篇 |
2018年 | 433篇 |
2017年 | 379篇 |
2016年 | 395篇 |
2015年 | 546篇 |
2014年 | 647篇 |
2013年 | 709篇 |
2012年 | 1132篇 |
2011年 | 1207篇 |
2010年 | 743篇 |
2009年 | 622篇 |
2008年 | 874篇 |
2007年 | 863篇 |
2006年 | 826篇 |
2005年 | 774篇 |
2004年 | 694篇 |
2003年 | 597篇 |
2002年 | 523篇 |
2001年 | 467篇 |
2000年 | 403篇 |
1999年 | 403篇 |
1998年 | 183篇 |
1997年 | 173篇 |
1996年 | 192篇 |
1995年 | 157篇 |
1994年 | 119篇 |
1993年 | 94篇 |
1992年 | 196篇 |
1991年 | 185篇 |
1990年 | 159篇 |
1989年 | 144篇 |
1988年 | 134篇 |
1987年 | 112篇 |
1986年 | 105篇 |
1985年 | 108篇 |
1984年 | 79篇 |
1983年 | 71篇 |
1982年 | 62篇 |
1981年 | 57篇 |
1980年 | 56篇 |
1979年 | 61篇 |
1978年 | 55篇 |
1977年 | 36篇 |
1975年 | 28篇 |
1974年 | 43篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease 下载免费PDF全文
2.
3.
4.
R. H. Wiesner B. J. Steffen K. M. David A. H. Chu R. D. Gordon J. R. Lake 《American journal of transplantation》2006,6(7):1609-1616
Mycophenolate mofetil (MMF) used in a triple-drug regimen has been shown to decrease acute rejection rates, compared to a double-drug regimen. The impact of MMF on late acute rejection (LAR) episodes has not been well described. To investigate the risk of LAR (rejection > or = 6 months post-transplantation) data from the Scientific Registry of Transplant Recipients (SRTR) were used. We studied adult primary liver transplant recipients transplanted between June 1, 1995, and April 30, 2004, with hepatitis C virus (HCV) (n = 3356), hepatitis B virus (HBV) (n = 550) or a nonviral (n = 5740) primary cause of liver disease who were recorded as receiving continuous 3-(MMF + Tacro + steroids) versus 2-drug (Tacro + steroids) therapy for at least 6 months immediately post transplantation. Kaplan-Meier analysis showed significantly lower LAR rates 4 years post-transplant in 3- versus 2-drug HCV, HBV and nonviral disease patients. Multivariate regression confirmed 3- versus 2-drug therapy to be associated with a decreased risk of LAR. Late graft survival was significantly lower at 4 years post-transplant for patients with LAR 6-12 months post-transplantation versus patients with early rejection (78.0% vs. 87.0%, p < 0.001) and no rejection (88.1%, p < 0.001). Three-drug versus 2-drug therapy for a minimum of 6 months may offer a better treatment strategy to avoid the consequences and expense of LAR episodes. 相似文献
5.
6.
K U Chu S Higashide B M Evers S Rajaraman J Ishizuka C M Townsend Jr J C Thompson 《Annals of surgery》1994,220(4):570-577
OBJECTIVE: The authors determined whether bombesin could improve survival from methotrexate (MTX)-induced enterocolitis. SUMMARY BACKGROUND DATA: Bombesin prevents gut mucosal atrophy, which is produced by feeding rats an elemental diet. Administration of MTX produces a lethal enterocolitis in rats fed an elemental diet. METHODS: On treatment day 0, 60 rats were divided randomly into three groups and fed an elemental diet (Vivonex TEN, Sandoz, Minneapolis, MN) as the only source of nutrition. Groups were subdivided further to receive either saline or bombesin (10 micrograms/kg, subcutaneously, three times a day) beginning either on day 0 or day 14. Methotrexate (20 mg/kg, intraperitoneally) was given to all rats 14 days after the start of an elemental diet. RESULTS: Bombesin prevented the mucosal atrophy in the ileum produced by the elemental diet and significantly decreased mortality in rats given MTX (whether given as a pretreatment or at the time of MTX administration). CONCLUSION: Bombesin significantly improved survival in a lethal model of MTX-induced enterocolitis, possibly by maintaining gut mucosal structure. Administration of bombesin to patients receiving chemotherapy may be clinically useful in preventing the severe enterocolitis induced by various chemotherapeutic agents. 相似文献
7.
王伏虎 《南京医科大学学报(英文版)》2002,16(2):49-64
Stroke is a debilitating disease that affects millions each year.While in many cases cerebral ischemic in jury can be limited by effectivw resuscitation or thrombolytic treatment,the injured neurons wither in a process known as delayed neuronal death(DND).Mounting evidence indicates that DND is not simply necrosis played out in slow motion but apoptosis is triggered.Of particular interest are two groups of signal proteins that participate in apoptosis-cyclin dependent kinases(CDKs) and p53-among a myriad of signaling events after an ischemic insult.Recent investigations have shown that CDKs,a family of enzymes initially known for their role in cell cycle regulation,are activated in injured neurons in DND.As for p53,new reports suggest that its up-regulation may represent a failed attempt to rescue in jured neurons,although its up-regulation was previously considered an indication of apoptosis.These observations thus rekindle an old quest to identify new neuroprotective targets to minimize the stroke damage.In this review,the author will examine the evidence that indicates the participation of CDKs and p53 in DND and then introduce pre-clinical data to explore CDK inhibition as a potential neuroprotective target.Finally,using CDK inhibition as an example,this paper will discuss the pertinent criteria for a viable neuroprotective strategy for ischemic in jury. 相似文献
8.
9.
初明利 《国际中华应用心理学杂志》2005,2(3):229-230
研究大学生心理素质与思想品德发展的关系,目的在于分析、发现个体在接受教育过程中的心理运动规律,从而提高思想教育的实效性。本文从马克思主义认识论和实践论的观点出发,依据教育心理学的原理,探讨了心理健康教育与思想品德教育的内在联系和相互作用,提出良好的心理素质是大学生思想品德发展的基础的观点。认为品德的形成与人的心理活动息息相关,个体如果没有良好的品德,将影响其心理素质的完善;同样,没有健全的心理素质,思想品德也不能得到很好的发展。只有思想品德教育与心理健康教育协调发展,共同作用,才能收到良好的教育效果。 相似文献
10.