全文获取类型
收费全文 | 443篇 |
免费 | 35篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 15篇 |
妇产科学 | 12篇 |
基础医学 | 92篇 |
口腔科学 | 5篇 |
临床医学 | 59篇 |
内科学 | 123篇 |
皮肤病学 | 5篇 |
神经病学 | 23篇 |
特种医学 | 28篇 |
外科学 | 35篇 |
综合类 | 6篇 |
预防医学 | 38篇 |
眼科学 | 1篇 |
药学 | 12篇 |
肿瘤学 | 24篇 |
出版年
2021年 | 5篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 5篇 |
2015年 | 9篇 |
2014年 | 4篇 |
2013年 | 6篇 |
2012年 | 7篇 |
2011年 | 9篇 |
2010年 | 7篇 |
2009年 | 15篇 |
2008年 | 20篇 |
2007年 | 21篇 |
2006年 | 14篇 |
2005年 | 19篇 |
2004年 | 11篇 |
2003年 | 20篇 |
2002年 | 11篇 |
2001年 | 17篇 |
2000年 | 17篇 |
1999年 | 32篇 |
1998年 | 15篇 |
1997年 | 13篇 |
1996年 | 18篇 |
1995年 | 9篇 |
1994年 | 19篇 |
1993年 | 11篇 |
1991年 | 4篇 |
1990年 | 4篇 |
1989年 | 11篇 |
1988年 | 12篇 |
1987年 | 8篇 |
1986年 | 5篇 |
1985年 | 10篇 |
1984年 | 6篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 5篇 |
1978年 | 4篇 |
1976年 | 6篇 |
1975年 | 2篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1971年 | 5篇 |
1969年 | 2篇 |
1965年 | 3篇 |
1963年 | 4篇 |
1962年 | 2篇 |
1956年 | 2篇 |
排序方式: 共有479条查询结果,搜索用时 31 毫秒
1.
2.
Suppurative corneal ulceration in Bangladesh 总被引:8,自引:0,他引:8
AAS Dunlop MB BS ED Wright MRCPath † SA Howlader‡ I Nazrul‡ R Husain‡ K McClellan FRACO § FA Billson FRACO § 《Clinical & experimental ophthalmology》1994,22(2):105-110
Suppurative keratitis is an important preventable cause of blindness, particularly in the developing world. This study analyses 142 cases of suppurative keratitis referred to Chittagong Eye Infirmary, Bangladesh. Some 53.5% of cases were bacterial and 35.9% were fungal. The five most common pathogens were: Pseudomonas sp. 24%, Streptococcus pneumoniae 17%, Aspergillus sp. 13%, Fusarium sp. 7% and Curvularia sp. 6%. Gram stain and culture results were consistent in 62.6% of cases. Previous antibiotic treatment was a significant factor for failure of culture isolation and less so for Gram stain failure. On Gram stain, 55.9% of pseudomonal cases were missed, but only 2% of fungal cases were missed. Over all, Gram stain had a sensitivity of 62% and positive predictive value of 84% for bacterial cases, and 98% and 94% for fungal cases, respectively. Fungal ulcers were typically filamentous, but an antecedent history of trauma was not common. The most frequent injury was due to rice grains, but the inoculum appeared to be introduced during eye washing with contaminated water. Pseudomonal ulcers occurred most frequently in the monsoon season, and Fusarium cases were seen only in the hot, dry season. 相似文献
3.
4.
5.
. We invited Dr Peplau to provide a personal reflection on the recent history of psychiatric nursing and her thoughts on immediate challenges facing the profession. The paper is an individual scholar's commentary on the way that psychiatry has waxed and waned over the years, in relation to nursing. This historical review discovers and reports a challenge to current practice. Dr Peplau describes a professional shift that is pulling nurses toward the subordinate role observed earlier this century. The paper draws attention to how contemporary practice can be positively influenced, e.g., by giving a structure to the allocation and conduct of nurse–patient time. 相似文献
6.
The adhesion of hematopoietic progenitor cells to bone marrow stromal cells is critical to hematopoiesis and involves multiple effector molecules. Stromal cell molecules that participate in this interaction were sought by analyzing the detergent-soluble membrane proteins of GBI/6 stromal cells that could be adsorbed by intact FDCP-1 progenitor cells. A single-chain protein from GBI/6 cells having an apparent molecular weight of 37 Kd was selectively adsorbed by FDCP-1 cells. This protein, designated p37, could be surface-radiolabeled and thus appeared to be exposed on the cell membrane. An apparently identical 37- Kd protein was expressed by three stromal cell lines, by Swiss 3T3 fibroblastic cells, and by FDCP-1 and FDCP-2 progenitor cells. p37 was selectively adsorbed from membrane lysates by a variety of murine hematopoietic cells, including erythrocytes, but not by human erythrocytes. Binding of p37 to cells was calcium-dependent, and was not affected by inhibitors of the hematopoietic homing receptor or the cell-binding or heparin-binding functions of fibronectin. It is proposed that p37 may be a novel adhesive molecule expressed on the surface of a variety of hematopoietic cells that could participate in both homotypic and heterotypic interactions of stromal and progenitor cells. 相似文献
7.
S Aractingi E Gluckman M C Dauge-Geffroy C Le Gou A Flahaut L Dubertret E Carosella 《Journal of clinical pathology》1997,50(4):305-309
AIMS: To measure Langerhans' cells in skin of patients treated by bone marrow transplantation who developed chronic graft versus host disease (GvHD); to determine whether the reduction in Langerhans' cells resulted directly from the GvHD or from other factors, such as the immunosuppressive regimens used in bone marrow transplant patients. PATIENTS AND METHODS: Lesional and nonlesional skin specimens from nine patients with lichen planus-like lesions and three patients with sclerodermoid lesions were studied. Control skin specimens were taken from three patients undergoing breast reduction surgery. The number of Langerhans' cells/mm2 and the area of Langerhans' cells as a percentage of total epidermis were measured by counting cells labelled with antihuman CD1a. RESULTS: A significant reduction in Langerhans' cell area and number were found in specimens with lesions (area 3.5%; number 507/mm2) compared with specimens without lesions (8.42%; 2375/mm2). In contrast, Langerhans' cell area and number in skin without lesions were similar to controls (10.26%; 2968/mm2). CONCLUSIONS: Langerhans' cells were significantly reduced in skin with lesions of chronic GvHD but not in skin without lesions from the same patient, suggesting that the reduction is a direct consequence of GvHD and not linked to immunosuppressive drugs or late effects of conditioning regimens. In long term bone marrow transplant recipients, Langerhans' cells are derived mainly from the donor cells; therefore, this result suggests the occurrence of autoreactive phenomenon in chronic GvHD. 相似文献
8.
9.
In vivo, RFX5 binds differently to the human leucocyte antigen-E, -F, and -G gene promoters and participates in HLA class I protein expression in a cell type-dependent manner 总被引:4,自引:0,他引:4 下载免费PDF全文
Rousseau P Masternak K Krawczyk M Reith W Dausset J Carosella ED Moreau P 《Immunology》2004,111(1):53-65
10.
Expression of HLA-G in human cornea, an immune-privileged tissue 总被引:11,自引:0,他引:11