全文获取类型
收费全文 | 20025篇 |
免费 | 983篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 220篇 |
儿科学 | 642篇 |
妇产科学 | 582篇 |
基础医学 | 2424篇 |
口腔科学 | 515篇 |
临床医学 | 1450篇 |
内科学 | 5332篇 |
皮肤病学 | 355篇 |
神经病学 | 2022篇 |
特种医学 | 835篇 |
外国民族医学 | 2篇 |
外科学 | 2581篇 |
综合类 | 58篇 |
一般理论 | 3篇 |
预防医学 | 925篇 |
眼科学 | 246篇 |
药学 | 1097篇 |
中国医学 | 15篇 |
肿瘤学 | 1830篇 |
出版年
2023年 | 139篇 |
2022年 | 290篇 |
2021年 | 501篇 |
2020年 | 284篇 |
2019年 | 415篇 |
2018年 | 521篇 |
2017年 | 380篇 |
2016年 | 505篇 |
2015年 | 509篇 |
2014年 | 719篇 |
2013年 | 926篇 |
2012年 | 1413篇 |
2011年 | 1394篇 |
2010年 | 810篇 |
2009年 | 745篇 |
2008年 | 1341篇 |
2007年 | 1227篇 |
2006年 | 1291篇 |
2005年 | 1187篇 |
2004年 | 1169篇 |
2003年 | 1059篇 |
2002年 | 980篇 |
2001年 | 246篇 |
2000年 | 209篇 |
1999年 | 270篇 |
1998年 | 205篇 |
1997年 | 175篇 |
1996年 | 145篇 |
1995年 | 146篇 |
1994年 | 125篇 |
1993年 | 139篇 |
1992年 | 166篇 |
1991年 | 138篇 |
1990年 | 129篇 |
1989年 | 116篇 |
1988年 | 108篇 |
1987年 | 111篇 |
1986年 | 107篇 |
1985年 | 70篇 |
1984年 | 96篇 |
1983年 | 60篇 |
1982年 | 71篇 |
1981年 | 62篇 |
1980年 | 47篇 |
1979年 | 40篇 |
1978年 | 41篇 |
1977年 | 30篇 |
1976年 | 23篇 |
1974年 | 24篇 |
1972年 | 26篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Carlo De-Carolis Geraldine-A. Boyd Luca Mancinelli Stefano Pagano Stefano Eramo 《Medicina oral, patología oral y cirugía bucal》2015,20(2):e205-e210
With easy chemical synthesis from its precursor, methamphetamine (MA) is now widespread in many countries. The abuse of methamphetamine is associated with several negative effects on health, because MA is a neurotoxin and a dangerous central nervous system stimulant. It changes levels of neurotransmitters in the brain, releasing dopamine and inhibiting nor epinephrine uptake which increases sympathetic nervous system activity and can lead to cardiac arrhythmia, hypertension and tachypnea. The consequences of MA abuse are clearly manifested in oral diseases (like “meth mouth”) which is characterised by extensive caries, teeth grinding with ensuing dental wear and trismus. The present review was designed to fill the gap in knowledge about methamphetamine abuse in the European Union (EU) and to illustrate the main clinical effects of prolonged use. After describing the pharmacology and systemic effects of methamphetamine and concentrating on its effects on the mouth, the present review compares the epidemiology and incidence of abuse in the world, particularly the USA and the EU.
Key words:Methamphetamine, “Meth mouth”, drug abuse, oral health. 相似文献
3.
Zaida Araujo Sietze Brandes Elena Pinelli María A. Bochichio Andrea Palacios Albina Wide Bruno Rivas-Santiago Juan Carlos Jiménez 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(1):47-55
The present study aimed at measuring seropositivities for infection by
Ascaris suum and Toxocara canis using the
excretory/secretory (E/S) antigens from Ascaris suum (AES) and
Toxocara canis (TES) within an indigenous population. In
addition, quantification of cytokine expressions in peripheral blood cells was
determined. A total of 50 Warao indigenous were included; of which 43 were adults and
seven children. In adults, 44.1% were seropositive for both parasites; whereas
children had only seropositivity to one or the other helminth. For ascariosis, the
percentage of AES seropositivity in adults and children was high; 23.3% and 57.1%,
respectively. While that for toxocariosis, the percentage of TES seropositivity in
adults and children was low; 9.3% and 14.3%, respectively. The percentage of
seronegativity was comparable for AES and TES antigens in adults (27.9%) and children
(28.6%). When positive sera were analyzed by Western blotting technique using AES
antigens; three bands of 97.2, 193.6 and 200.2 kDas were mostly recognized. When the
TES antigens were used, nine major bands were mostly identified; 47.4, 52.2, 84.9,
98.2, 119.1, 131.3, 175.6, 184.4 and 193.6 kDas. Stool examinations showed that
Blastocystis hominis, Hymenolepis nana and
Entamoeba coli were the most commonly observed intestinal
parasites. Quantification of cytokines IFN-γ, IL-2, IL-6, TGF-β, TNF-α, IL-10 and
IL-4 expressions showed that there was only a significant increased expression of
IL-4 in indigenous with TES seropositivity (p < 0.002).
Ascaris and Toxocara seropositivity was
prevalent among Warao indigenous. 相似文献
4.
5.
6.
7.
8.
Darren R. Feldman MD Yasser Ged MBBS Chung-Han Lee PhD Andrea Knezevic MS Ana M. Molina MD Ying-Bei Chen PhD Joshua Chaim DO Devyn T. Coskey MS Samuel Murray MS Satish K. Tickoo MD Victor E. Reuter MD Sujata Patil PhD Han Xiao MD Jahan Aghalar MD Arlyn J. Apollo MD Maria I. Carlo MD Robert J. Motzer MD Martin H. Voss MD 《Cancer》2020,126(24):5247-5255
9.
Carlo Bertucci Enrico Domenici Piero Salvadori 《Journal of pharmaceutical and biomedical analysis》1990,8(8-12):843-846
The application of a circular dichroism (c.d.) detection system in HPLC using a chiral stationary phase is presented. The simultaneous measurement of the absorbance and c.d. signal allows the evaluation of the anisotropy factor (g = Δ/) and thus the determination of the enantiomeric excess (e.e.) of the eluates. When this detection system is used in preparative chiral chromatography the collection of the enantiomeric fractions can be readily optimized. 相似文献
10.