全文获取类型
收费全文 | 4004篇 |
免费 | 581篇 |
国内免费 | 85篇 |
专业分类
耳鼻咽喉 | 43篇 |
儿科学 | 154篇 |
妇产科学 | 80篇 |
基础医学 | 495篇 |
口腔科学 | 53篇 |
临床医学 | 413篇 |
内科学 | 1079篇 |
皮肤病学 | 48篇 |
神经病学 | 421篇 |
特种医学 | 225篇 |
外科学 | 546篇 |
综合类 | 114篇 |
预防医学 | 465篇 |
眼科学 | 100篇 |
药学 | 264篇 |
1篇 | |
中国医学 | 1篇 |
肿瘤学 | 168篇 |
出版年
2021年 | 46篇 |
2019年 | 34篇 |
2017年 | 33篇 |
2015年 | 50篇 |
2014年 | 56篇 |
2013年 | 80篇 |
2012年 | 123篇 |
2011年 | 129篇 |
2010年 | 74篇 |
2009年 | 78篇 |
2008年 | 104篇 |
2007年 | 154篇 |
2006年 | 126篇 |
2005年 | 163篇 |
2004年 | 130篇 |
2003年 | 97篇 |
2002年 | 111篇 |
2001年 | 103篇 |
2000年 | 100篇 |
1999年 | 104篇 |
1998年 | 58篇 |
1997年 | 65篇 |
1996年 | 63篇 |
1995年 | 55篇 |
1994年 | 60篇 |
1993年 | 54篇 |
1992年 | 108篇 |
1991年 | 101篇 |
1990年 | 125篇 |
1989年 | 135篇 |
1988年 | 130篇 |
1987年 | 129篇 |
1986年 | 138篇 |
1985年 | 132篇 |
1984年 | 118篇 |
1983年 | 137篇 |
1982年 | 92篇 |
1981年 | 90篇 |
1980年 | 83篇 |
1979年 | 111篇 |
1978年 | 88篇 |
1977年 | 78篇 |
1976年 | 54篇 |
1975年 | 58篇 |
1974年 | 49篇 |
1973年 | 41篇 |
1972年 | 46篇 |
1971年 | 49篇 |
1970年 | 49篇 |
1969年 | 35篇 |
排序方式: 共有4670条查询结果,搜索用时 0 毫秒
1.
Hepatitis C virus (HCV) infection is a major health care issue in liver and kidney transplantation. Besides negatively affecting both patient and graft survival, HCV is associated with a heightened risk for new onset diabetes mellitus (NODM). The mechanisms underlying the diabetogenicity of HCV are complex but are likely to involve insulin resistance caused by inhibitory actions of the virus on insulin regulatory pathways in the liver. The resultant glucose dysregulation is an important determinant of increased morbidity and mortality in liver and kidney recipients. This review highlights the concerns for outcomes in HCV-positive liver and kidney transplant patients with particular focus on the interrelationship between hepatitis C and diabetes. Data about the potential role of calcineurin inhibitors, corticosteroids and mycophenolate mofetil in HCV infection and HCV-associated NODM will also be discussed. 相似文献
2.
R W Hertle A B Leahey S Bloom D B Schaffer S Bartlett 《Ophthalmic plastic and reconstructive surgery》1990,6(4):278-282
Chorioretinal folds have been reported as a result of many intraocular and extraocular inflammatory processes or tumors. Visual loss is usually secondary to a combination of the underlying process and chorioretinal folds involving the macula. We report a patient who developed decreased vision, metamorphopsia, chorioretinal folds, and a lamellar macular hole secondary to global compression by a bone fragment. The chorioretinal folds regressed and his vision stabilized following surgical decompression. Chorioretinal folds and lamellar macular hold formation are previously unrecognized complications of reconstructive craniofacial surgery. 相似文献
3.
4.
5.
D J Brooks J S Gibbs P Sharp S Herold D R Turton S K Luthra E M Kohner S R Bloom T Jones 《Journal of cerebral blood flow and metabolism》1986,6(2):240-244
Regional cerebral [11C]3-O-methyl-D-glucose ([11C]MeG) uptake kinetics have been measured in five insulin-dependent diabetic patients and four normal controls using positron emission tomography (PET). Concomitant measurement of regional cerebral blood volume and CBF enabled corrections for the presence of intravascular [11C]MeG signal in cerebral regions of interest to be carried out, and regional cerebral [11C]MeG unidirectional extraction fractions to be computed. Four of the five diabetic subjects were studied with their fasting plasma glucose level clamped at a normoglycaemic level (4 mM), and four were studied at hyperglycaemic plasma glucose levels (mean 13 mM). The four diabetic subjects whose fasting plasma glucose levels were clamped at a normoglycaemic level of 4 mM had mean fasting whole-brain, cortical, and white matter [11C]MeG extraction fractions of 15, 15, and 16%, respectively, values similar to those found for the four normal controls (whole brain, 14%; cortex, 13%; white matter, 17%). Mean regional cerebral [11C]MeG extraction fractions were significantly reduced in diabetic subjects during hyperglycaemia whether their plasma insulin levels were undetectable or whether they were raised by continuous intravenous insulin infusion. Such a reduction in [11C]MeG extraction under hyperglycaemic conditions can be explained entirely in terms of increased competition between [11C]MeG and D-glucose for the passive facilitated transport carrier system for hexoses across the blood-brain barrier (BBB). It is concluded that the number and affinity of D-glucose carriers present in the BBB are within normal limits in treated insulin-dependent diabetic subjects. In addition, insulin appears to have no effect on the transport of D-glucose across the BBB. 相似文献
6.
7.
8.
9.
Retroperitoneal Laparoscopic Nephrectomy in Children 总被引:1,自引:0,他引:1
David A. Diamond Howard M. Price Elspeth M. McDougall David A. Bloom 《The Journal of urology》1995,153(6):1966-1968
Retroperitoneal pediatric laparoscopic nephrectomy is described in 3 patients requiring 3 to 5 hours with an estimated blood loss of 10 to 60 cc. The children returned to school within 7 days postoperatively. Advantages of this procedure include the avoidance of intraoperative repositioning of the patient and easy conversion to an open lumbodorsal approach, if necessary; early laparoscopic visualization of the renal artery; applicability in cases of previous abdominal surgery, and avoidance of intraperitoneal adhesion. 相似文献
10.