全文获取类型
收费全文 | 1437篇 |
免费 | 136篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 81篇 |
妇产科学 | 14篇 |
基础医学 | 184篇 |
口腔科学 | 61篇 |
临床医学 | 146篇 |
内科学 | 347篇 |
皮肤病学 | 42篇 |
神经病学 | 85篇 |
特种医学 | 160篇 |
外国民族医学 | 1篇 |
外科学 | 105篇 |
综合类 | 51篇 |
一般理论 | 1篇 |
预防医学 | 121篇 |
眼科学 | 13篇 |
药学 | 100篇 |
中国医学 | 4篇 |
肿瘤学 | 59篇 |
出版年
2022年 | 7篇 |
2021年 | 9篇 |
2020年 | 16篇 |
2019年 | 20篇 |
2018年 | 25篇 |
2017年 | 20篇 |
2016年 | 19篇 |
2015年 | 30篇 |
2014年 | 29篇 |
2013年 | 41篇 |
2012年 | 50篇 |
2011年 | 49篇 |
2010年 | 40篇 |
2009年 | 59篇 |
2008年 | 48篇 |
2007年 | 41篇 |
2006年 | 41篇 |
2005年 | 42篇 |
2004年 | 54篇 |
2003年 | 26篇 |
2002年 | 33篇 |
2001年 | 26篇 |
2000年 | 30篇 |
1999年 | 31篇 |
1998年 | 63篇 |
1997年 | 69篇 |
1996年 | 62篇 |
1995年 | 48篇 |
1994年 | 43篇 |
1993年 | 39篇 |
1992年 | 33篇 |
1991年 | 33篇 |
1990年 | 34篇 |
1989年 | 20篇 |
1988年 | 26篇 |
1987年 | 39篇 |
1986年 | 34篇 |
1985年 | 22篇 |
1984年 | 19篇 |
1983年 | 18篇 |
1982年 | 30篇 |
1981年 | 10篇 |
1980年 | 17篇 |
1979年 | 18篇 |
1978年 | 7篇 |
1977年 | 7篇 |
1976年 | 15篇 |
1975年 | 7篇 |
1969年 | 7篇 |
1968年 | 9篇 |
排序方式: 共有1583条查询结果,搜索用时 31 毫秒
1.
2.
Intrathecal morphine in an average dose of 0.01 mg/kg was given to 33 patients between ages 11 and 16 years who had spinal arthrodesis for idiopathic scoliosis. The morphine was administered intrathecally as a 10 cc bolus at the conclusion of the arthrodesis, but before closure. The goal was to study safety in terms of respiratory depression and pain relief. Respirations occurred spontaneously in 30 of the 33 patients within 15 minutes of cessation of anesthesia. Respiratory depression occurred in five patients, four of whom had arterial blood pCO2 levels greater than 60 mm Hg. Thirty-one patients had relief of pain for 8 to greater than 40 hours, averaging 18 hours. Two patients had no noticeable pain relief. There appeared to be no relation between dose and pain relief in this limited dose range. We were unable to duplicate the long duration of pain relief reported elsewhere. We also were unable to decrease the side effects of respiratory depression and nausea to a level reported by others. It may be that the 10 cc bolus injected intrathecally circulates to the brain and ventricles faster than desired, or that factors relating to type of anesthesia or dose need to be considered. Low-dose intrathecal morphine does provide noticeable pain relief in younger patients undergoing spinal fusion. The side effects of nausea and respiratory depression can be managed safely with medication. 相似文献
3.
4.
5.
Ketai LH; Williamson MR; Telepak RJ; Levy H; Koster FT; Nolte KB; Allen SE 《Radiology》1994,191(3):665
6.
7.
J R Blackman S Dillon 《The Journal of the American Board of Family Practice / American Board of Family Practice》1992,5(4):399-405
BACKGROUND: Venomous snakebites continue to cause great morbidity, and treatment options are confusing the attending physician. In the United States approximately 45,000 snakebites occur each year, of which some 8000 are by 20 species of venomous snakes. METHODS: Information on venomous snakes and snakebite treatment was gathered from the libraries of the Wilderness Medical Society and the Rocky Mountain Center for Wilderness Medicine in Boise, Idaho (co-supported by the Boise State University and the Family Practice Residency of Idaho), as well as from current literature files of physicians practicing wilderness medicine. RESULTS AND CONCLUSIONS: Three genera of venomous snakes account for the majority of poisonous snake envenomations in this country. Most hospitalized victims are bitten either by rattlesnakes or copperheads or by unidentified snakes. Most of these bites occur during the summer months and are found on the extremities. Field treatment focuses on the application of a vacuum extractor and transportation to the nearest medical facility. Although constriction band use can be helpful, tourniquets, incision and suction, and ice therapy are contraindicated. Electric shock therapy is of no use and could cause serious injury. Hospital management focuses on rapid clinical evaluation and laboratory tests to establish the degree of envenomation, looking for clotting abnormalities. If envenomation has occurred and is reactive, polyvalent antivenin should be administered according to the degree of envenomation. Errors in diagnosis and treatment result in increased morbidity and put attending physicians at risk for litigation. Prevention remains the most successful approach to snakebite management. 相似文献
8.
9.
M J Blackman I T Ling S C Nicholls A A Holder 《Molecular and biochemical parasitology》1991,49(1):29-33
The amino-terminal sequence has been obtained for 2 fragments of the Plasmodium falciparum T9/94 merozoite surface protein precursor (PfMSP1) and these have been compared with the sequence predicted from the gene. These data define the position of these fragments in the precursor and indicate that the C-terminal sequence which is carried into the red cell during invasion consists of 2 epidermal growth factor (EGF)-like domains. A homologous cleavage sequence and domain structure can be identified in the MSP1 molecules of other malarial species. In addition the results suggest that the smaller fragment is not N-glycosylated. 相似文献
10.
M J Busby M F Bellantoni J D Tobin D C Muller S D Kafonek M R Blackman R Andres 《Journal of the American Geriatrics Society》1992,40(5):497-502
OBJECTIVE: To determine the separate and interactive effects of age, phase of the menstrual cycle, menopausal hormone status, body fat mass, and regional fat distribution on glucose tolerance in healthy women. DESIGN: Retrospective study. SETTING: The Baltimore Longitudinal Study of Aging. PATIENTS: Two hundred sixty healthy women aged 22-89 years. MEASUREMENTS: Plasma levels of estradiol and progesterone, body mass index (BMI), waist-to-hip ratio (WHR), and plasma glucose values in the fasting state (FPG) as well as 120 minutes after 40 gm/m2 of oral glucose (G120) were measured for each participant. RESULTS: We found a progressive decline in oral glucose tolerance of 0.4 mM (6.7 mg/dL)/decade at G120) in women from early to late adult years, with no relationship to phase of the menstrual cycle and no abrupt change associated with the menopause. Multiple regression analysis revealed significant, independent effects of BMI and WHR on FPG and G120. The influence of age (P less than 0.01) on G120 was stronger than that of the BMI or WHR (P less than 0.05). There was no significant relationship between the levels of endogenous sex hormones and glucose tolerance after adjustments for age, BMI, and WHR. However, women taking oral contraceptives, but not those receiving postmenopausal replacement therapy, did exhibit mildly elevated G120 values. CONCLUSIONS: Age per se, and to a lesser extent BMI and WHR, but not levels of endogenous sex steroids, contribute to the physiological decline in glucose tolerance in older women. 相似文献