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Marti Matteo Neri Margherita Bilel Sabrine Di Paolo Marco La Russa Raffaele Ossato Andrea Turillazzi Emanuela 《Forensic Toxicology》2019,37(1):132-144
Forensic Toxicology - MDMA is a psychoactive drug that has been increasingly abused worldwide, due to its entactogenic properties. However, concerns on its safety exist, particularly regarding its... 相似文献
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In this paper, we propose a H.264/AVC based compression technique adapted to coronary angiograms. H.264/AVC coder has proven to use the most advanced and accurate motion compensation process, but, at the cost of high computational complexity. On the other hand, analysis of coronary X-ray images reveals large areas containing no diagnostically important information. Our contribution is to exploit the energy characteristics in slice equal size regions to determine the regions with relevant information content, to be encoded using the H.264 coding paradigm. The others regions, are compressed using fixed block motion compensation and conventional hard-decision quantization. Experiments have shown that at the same bitrate, this procedure reduces the H.264 coder computing time of about 25% while attaining the same visual quality. A subjective assessment, based on the consensus approach leads to a compression ratio of 30:1 which insures both a diagnostic adequacy and a sufficient compression in regards to storage and transmission requirements. 相似文献
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Médéa Locquet Bilel Benhotman Stephen Bornheim Julien Van Beveren Pieter D’Hooghe Olivier Bruyère Jean-François Kaux 《Foot and Ankle Surgery》2021,27(1):70-76
BackgroundFunctional ankle instability affects 20–40% of individuals who have already suffered from a sprain. Such dysfunctions are difficult to diagnose. Therefore, the information provided by self-administered questionnaires is essential. Thus, the Ankle Instability Instrument (AII) was developed and initially validated in English. Our goal is to create a French version of the instrument, named AII-F, by scrupulously respecting the cultural adaptation phases and to make sure the new instrument has good psychometric properties.MethodsInternational recommendations have been rigorously followed for the cultural adaptation and the French-translation phase. Six steps are recommended: I) two initial translations from English to French; II) synthesis of the two versions; III) back-translations from French to English; IV) comparisons between the back-translations and the original questionnaire by the expert committee; V) pretest; and VI) approval of the final French version of the AII. In order to validate this French-translation, 91 subjects suffering from ankle instability matched to 91 healthy subjects were asked to complete the AII-F. The Short Form Health Survey (SF-36) was used as a comparative questionnaire as well as the French Cumberland Ankle Instability Tool (CAIT-F). The psychometric properties of the questionnaire were evaluated by determining the test-retest reliability after a 10–14-day interval, the internal consistency, construct validity, and the floor/ceiling effects.ResultsThe French-translation did not pose a problem and could be validated by the expert committee. The AII-F showed a very good test-retest reliability for the total score, with an Intra Class Coefficient of 0.983. The internal coherence is high with an alpha coefficient of Cronbach of 0.861. The association of the AII-F with the CAIT-F was high, for the summary of the physical component of the SF-36, meaning a great convergent validity. The other subscales of the SF-36 (mental health) were weakly correlated with the AII-F, reflecting good divergent validity. An optimal cut-off score was obtained to dissociate pathological patients from healthy subjects: when the subject responded to “yes” 5 times or more, he is considered, with a very high degree of confidence, to be pathological.ConclusionThe AII-F is reliable and valid for evaluating and measuring functional ankle instability. 相似文献
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Karima Daghor Abbaci Nadia Ait Hamadouche Fifi Otmani Chafia Dahou Makhloufi Farida Mechid Mohamed Makrelouf Amel Otmane Nourredine Smail Malika Boucelma Fatma Zohra Aissat Salima Lefkir-Teffiani Bilel Bengana Nadia Boukheris Amar Tebaibia Baya Taharbouchet Soraya Ayoub Brahim Benziane Nadia Oumnia Chafika Haouichet Fella Hanni Nazim Laraba Djennete Hakem Nacera Benfenatki Abdelkrim Berrah 《Medicine》2022,101(32)
This study was performed to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in the diagnosis of adult onset Still disease (AOSD) and its performance to improve the sensitivity of the classifications criteria (Yamaguchi and Fautrel Classifications).We conducted a multicenter prospective nationwide case-control study in Internal medicine, Rheumatology and Infectious disease departments, to include successively patients with suspected AOSD (2 or more major criteria of Yamaguchi or Fautrel classifications). All clinical and biological features were collected in a consensual and standardized clinical assessment at baseline and during follow-up. A receiving operating characteristic (ROC) curve was used to reassess the cutoff value of NLR. After determination of the cutoff value for NLR by ROC curve, 2 composite sets (Yamaguchi classification + NLR as a major criterion and Fautrel classification + NLR as a major criterion) were performed and evaluated.One hundred sixty patients were included, 80 patients with AOSD and 60 controls with different diagnoses. Twenty patients with incomplete data were excluded. The cutoff value for NLR equals 4 (area under the curve, AUC: 0.82). The NLR was ≥ 4 in 93.7% (75/80) of AOSD patients with a sensitivity of 93.8% and specificity of 61.7%. The association of NLR as a major criterion with the classification of Yamaguchi or Fautrel improved their sensitivity, respectively for Fautrel (76.3% to 92.5%, P = .004) and Yamaguchi (78.8% to 90%, P = .05).This study validates the NLR as a good simple biomarker of AOSD with a cutoff value of 4 and high sensitivity (93.8%). The addition of NLR (NLR ≥ 4) as a major criterion to the classifications (Yamaguchi and Fautrel) improved significantly their sensitivity and accuracy. 相似文献
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Joseph T. Brooks Naoru Koizumi Elizabeth Neglia Bilel Gdoura Tina W. Wong Chang Kwon Tony E. Smith Jorge Ortiz 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2018,20(7):649-657
Background
Share 35 prioritizes offers of deceased donor livers to regional candidates with Model for End-Stage Liver Disease (MELD) ≥35 over local candidates with lower MELD scores. Analysis of Share35 has shown that overall 1- or 2-year post-transplant (LTx) outcomes have been unchanged while waitlist mortality has been reduced. However, these studies exclude retransplant (reLTx) recipients. This study aims to investigate the outcomes of liver retransplants in evaluating the impact of the Share35 policy.Methods
A retrospective analysis of data from the United Network for Organ Sharing database over the period June 2011–June 2015 was performed.Results
A total of 19,748 LTx and 312 reLTx recipients were identified. Of the LTx recipients, 9626 (48.7%) underwent transplant pre-Share 35 and 10,122 (51.3%) post-Share 35. 123 (39.4%) reLTx recipients underwent retransplantation pre-Share 35 and 189 (60.6%) post-Share 35. ReLTx recipients experienced improved 2-year graft survival post-Share 35 compared to pre-Share 35 (67% vs. 21.1%). Patient survival also improved at 2-years for reLTx recipients post-Share 35 compared to pre-Share 35 (69.2% vs. 33.1%). Transplant post-Share 35 was protective for both 2-year graft (HR = 0.669, CI = 0.454–0.985, p = 0.04) and patient (HR = 0.659, CI = 0.44–0.987, p = 0.003) survival.Conclusion
Share35 is associated with improved outcomes after retransplantation. 相似文献9.
Bilel Azeza Mohamed Helmi Hadj Alouane Bouraoui Ilahi Gilles Patriarche Larbi Sfaxi Afif Fouzri Hassen Maaref Ridha M’ghaieth 《Materials》2015,8(7):4544-4552
This paper reports on an initial assessment of the direct growth of In(Ga)As/GaAs quantum dots (QDs) solar cells on nanostructured surface Si substrate by molecular beam epitaxy (MBE). The effect of inserting 40 InAs/InGaAs/GaAs QDs layers in the intrinsic region of the heterojunction pin-GaAs/n+-Si was evaluated using photocurrent spectroscopy in comparison with pin-GaAs/n+-Si and pin-GaAs/GaAs without QDs. The results reveal the clear contribution of the QDs layers to the improvement of the spectral response up to 1200 nm. The novel structure has been studied by X ray diffraction (XRD), photoluminescence spectroscopy (PL) and transmission electron microscopy (TEM). These results provide considerable insights into low cost III-V material-based solar cells. 相似文献
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Hamdy Dosoky Elayouty Abd Alkader Mohamed Ba Yazeed Azeza Sayed Omar 《Indian Journal of Thoracic and Cardiovascular Surgery》2012,28(2):127-131