全文获取类型
收费全文 | 1495篇 |
免费 | 122篇 |
国内免费 | 29篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 65篇 |
妇产科学 | 33篇 |
基础医学 | 114篇 |
口腔科学 | 60篇 |
临床医学 | 186篇 |
内科学 | 250篇 |
皮肤病学 | 15篇 |
神经病学 | 142篇 |
特种医学 | 262篇 |
外科学 | 132篇 |
综合类 | 38篇 |
预防医学 | 114篇 |
眼科学 | 7篇 |
药学 | 162篇 |
中国医学 | 2篇 |
肿瘤学 | 54篇 |
出版年
2021年 | 10篇 |
2019年 | 9篇 |
2018年 | 19篇 |
2017年 | 13篇 |
2015年 | 22篇 |
2014年 | 23篇 |
2013年 | 19篇 |
2012年 | 17篇 |
2011年 | 36篇 |
2010年 | 43篇 |
2009年 | 27篇 |
2008年 | 25篇 |
2007年 | 47篇 |
2006年 | 43篇 |
2005年 | 33篇 |
2004年 | 35篇 |
2003年 | 39篇 |
2002年 | 25篇 |
2001年 | 35篇 |
2000年 | 31篇 |
1999年 | 27篇 |
1998年 | 67篇 |
1997年 | 78篇 |
1996年 | 83篇 |
1995年 | 54篇 |
1994年 | 45篇 |
1993年 | 47篇 |
1992年 | 29篇 |
1991年 | 38篇 |
1990年 | 39篇 |
1989年 | 59篇 |
1988年 | 59篇 |
1987年 | 38篇 |
1986年 | 45篇 |
1985年 | 51篇 |
1984年 | 22篇 |
1983年 | 26篇 |
1982年 | 20篇 |
1981年 | 21篇 |
1980年 | 16篇 |
1979年 | 13篇 |
1978年 | 11篇 |
1977年 | 22篇 |
1976年 | 16篇 |
1975年 | 11篇 |
1973年 | 8篇 |
1969年 | 10篇 |
1968年 | 11篇 |
1967年 | 11篇 |
1966年 | 11篇 |
排序方式: 共有1646条查询结果,搜索用时 330 毫秒
1.
Isolated patellofemoral arthritis is an increasingly recognized entity, and is usually associated with previous patellofemoral dysplasia or instability. Patellofemoral arthroplasty (PFA) has evolved significantly in recent years, both in terms of implant design and importantly in the understanding of appropriate patient selection. This review outlines the indications and investigations for PFA, provides a brief history of the development of contemporary implants, and presents the clinical outcomes for the prostheses most commonly used in the UK. In addition, it provides a detailed surgical technique for implantation of an onlay implant, with tips on how to optimize patellofemoral biomechanics and thus achieve a consistently good outcome. 相似文献
2.
3.
Sonoelasticity imaging of prostate cancer: in vitro results 总被引:2,自引:0,他引:2
4.
5.
6.
7.
8.
The purpose of the study was to evaluate the agonist and antagonist stimulus properties of the mixed opioid agonist antagonists butorphanol and nalbuphine in opioid-dependent subjects. Opioid-dependent volunteers (methadone 30 mg/day, PO) were trained in a three-choice drug discrimination procedure to discriminate between the effects of saline (2 ml), hydromorphone (10 mg/70 kg) and naloxone (0.15 mg/70 kg) administered IM. Subjects earned monetary reinforcement for correctly identifying the training drugs by letter code. Other subjective, behavioral and physiological measures were also collected. Hydromorphone and naloxone increased drug-appropriate responses and other characteristic subjective effects measures. Butorphanol and nalbuphine produced increases in naloxone-appropriate discrimination responding and in those subjective effect measures increased by naloxone. Butorphanol produced greater than 80% naloxone-appropriate responding at 1.05 mg/70 kg; nalbuphine produced 100% naloxone-appropriate responding at 2.1 mg/70 kg. Neither butorphanol nor nalbuphine showed opioid agonist-like effects in these subjects maintained at moderate levels of physical dependence. In opioid-dependent subjects, the stimulus effects of butorphanol and nalbuphine are antagonist-like. 相似文献
9.
Ten thrombocytopenic patients (platelets < 10–24 × 10(9)/L) who were refractory to platelet transfusion were investigated for their responsiveness to staphylococcal protein A column therapy. Nine patients had previously been treated with steroids, intravenous immune globulin, and/or other forms of immunosuppressive therapy without improvement in their transfusion response. All patients were receiving multiple platelet transfusions without achieving 1-hour corrected count increments (CCIs) > or = 7500. Eight patients had antibodies that reacted with platelets and were directed against HLA class I antigens, ABO antigens, and/or platelet-specific alloantigens. Plasma (500-2000 mL) from each patient was passed over a protein A silica gel column and then returned to the patient. Patients received from 1 to 14 treatments. A positive response to protein A therapy was defined as at least a doubling of the pretreatment platelet count and/or two successive 10- to 120-minute posttransfusion CCIs > or = 7500. Following plasma treatments, 6 of 10 patients responded with daily platelet counts that averaged 48 +/− 11 × 10(9) per L as compared with counts of 16 +/− 7 × 10(9) per L (p < 0.0005) before treatment. Posttransfusion CCI values determined in four of these patients averaged 2480 +/− 810 and 10,010 +/− 3540 (p < 0.005) before and after treatment, respectively. In contrast, among the four unresponsive patients, platelet counts averaged 10 +/− 9 and 13 +/− 10 × 10(9) per L (p = NS), respectively, while posttransfusion CCIs were 700 +/− 1410 and 1520 +/− 2460 (p = NS), respectively.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
10.
目的 探索LDH实验检测细胞活力的可行性。方法 原代培养骨髓细胞和软骨细胞,用LDH实验测定上述两组细胞的活力,并与镜下活体观察到细胞的生长状况相比较。与目前比较成熟的测定细胞活力的MTS实验的测得的值相比较。结果 LDH实验对上述两组细胞的活力的测定结果与镜下活体观察到的结果相符合。与MTS实验的测得的结果经统计学处理无显著差异。结论 LDH实验可用于细胞活力的直接测定,而对活细胞的生存、繁殖无影响。 相似文献