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Marco Zecca Cesare Perotti Pierluigi Marradi Daniela Montagna Giovanna Giorgiani RITA BALTER Luisella Prete & Franco Locatell i 《British journal of haematology》1996,92(2):432-434
Two children affected by severe aplastic anaemia and sickle cell anaemia rejected the allogeneic bone marrow transplantation from an HLA-matched unrelated volunteer and an HLA-identical sibling, respectively. In both cases a second transplant using granulocyte-colony stimulating factor (G-CSF) mobilized peripheral blood stem cells (PBSC) was performed. Donors were the HLA-haploidentical mother and the same HLA-identical sibling who was employed for the first marrow allograft, respectively. Treatment with G-CSF and PBSC collection were well tolerated. Both patients had engraftment of donor haemopoiesis and did not experience severe graft-versus-host disease. These cases confirm that PBSC transplant should be considered as a feasible treatment to reverse graft failure in paediatric patients. 相似文献
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BALTER M 《Annales de dermatologie et de syphiligraphie》1955,82(6):640-645
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