全文获取类型
收费全文 | 3982篇 |
免费 | 248篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 114篇 |
儿科学 | 73篇 |
妇产科学 | 113篇 |
基础医学 | 636篇 |
口腔科学 | 299篇 |
临床医学 | 309篇 |
内科学 | 954篇 |
皮肤病学 | 87篇 |
神经病学 | 271篇 |
特种医学 | 46篇 |
外国民族医学 | 1篇 |
外科学 | 399篇 |
综合类 | 23篇 |
预防医学 | 329篇 |
眼科学 | 109篇 |
药学 | 335篇 |
中国医学 | 20篇 |
肿瘤学 | 128篇 |
出版年
2023年 | 31篇 |
2022年 | 99篇 |
2021年 | 215篇 |
2020年 | 96篇 |
2019年 | 124篇 |
2018年 | 158篇 |
2017年 | 110篇 |
2016年 | 117篇 |
2015年 | 129篇 |
2014年 | 179篇 |
2013年 | 197篇 |
2012年 | 319篇 |
2011年 | 315篇 |
2010年 | 171篇 |
2009年 | 113篇 |
2008年 | 231篇 |
2007年 | 258篇 |
2006年 | 205篇 |
2005年 | 184篇 |
2004年 | 160篇 |
2003年 | 169篇 |
2002年 | 146篇 |
2001年 | 39篇 |
2000年 | 35篇 |
1999年 | 40篇 |
1998年 | 23篇 |
1997年 | 15篇 |
1996年 | 14篇 |
1995年 | 11篇 |
1994年 | 16篇 |
1993年 | 11篇 |
1992年 | 17篇 |
1991年 | 9篇 |
1990年 | 15篇 |
1989年 | 15篇 |
1988年 | 15篇 |
1987年 | 14篇 |
1986年 | 9篇 |
1985年 | 15篇 |
1984年 | 16篇 |
1983年 | 7篇 |
1982年 | 10篇 |
1981年 | 8篇 |
1980年 | 7篇 |
1979年 | 9篇 |
1974年 | 6篇 |
1971年 | 7篇 |
1926年 | 7篇 |
1913年 | 7篇 |
1912年 | 6篇 |
排序方式: 共有4246条查询结果,搜索用时 15 毫秒
1.
Bień Agnieszka Rzońca Ewa Zarajczyk Marta Wilkosz Katarzyna Wdowiak Artur Iwanowicz-Palus Grażyna 《Quality of life research》2020,29(10):2669-2677
Quality of Life Research - The aim of the study was to assess QoL and identify and analyse its determinants in women with endometriosis. The study was performed in 2019 in health centres in Lublin... 相似文献
2.
The Transient Receptor Potential Vanilloid 1 Antagonist Capsazepine Improves the Impaired Lung Mechanics during Endotoxemia 下载免费PDF全文
Layla D. M. Cabral Alexandre Giusti‐Paiva 《Basic & clinical pharmacology & toxicology》2016,119(5):421-427
Acute lung injury (ALI) caused by systemic inflammatory response remains a leading cause of morbidity and mortality in critically ill patients. Management of patients with sepsis is largely limited to supportive therapies, reflecting an incomplete understanding of the underlying pathophysiology. Furthermore, there have been limited advances in the treatments for ALI. In this study, lung function and a histological analysis were performed to evaluate the impact of transient receptor potential vanilloid‐1 receptor (TRPV1) antagonist (capsazepine; CPZ) on the lipopolysaccharide (LPS)‐induced lung injury in mice. For this, adult mice pre‐treated with CPZ or vehicle received intraperitoneal injections of LPS or saline and 24 hr after, the mice were anaesthetized, and lung mechanics was evaluated. The LPS‐challenged mice exhibited substantial mechanical impairment, characterized by increases in respiratory system resistance, respiratory system elastance, tissue damping and tissue elastance. The pre‐treatment with CPZ prevented the increase in respiratory system resistance and decreased the increase in tissue damping during endotoxemia. In addition, mice pre‐treated with CPZ had an attenuated lung injury evidenced by reduction on collapsed area of the lung parenchyma induced by LPS. This suggests that the TRPV1 antagonist capsazepine has a protective effect on lung mechanics in ALI during endotoxemia and that it may be a target for enhanced therapeutic efficacy in ALI. 相似文献
3.
4.
John Lennon Silva Cunha Amanda Almeida Leite Thamiris de Castro Abrantes Lorena Passoni Vervloet Thayn Melo de Lima Morais Gerson de Oliveira Paiva Neto Tatiana Nayara Librio Kimura Snia Maria Soares Ferreira Ricardo Luiz Cavalcanti de Albuquerque‐Júnior Aline Corrêa Abraho Mario Jos Romaach Bruno Augusto Benevenuto de Andrade Oslei Paes de Almeida Ciro Dantas Soares 《Journal of cutaneous pathology》2021,48(1):24-33
5.
Thaís dos Santos Fontes Pereira Carolina Cavalieri Gomes Peter A Brennan Felipe Paiva Fonseca Ricardo Santiago Gomez 《Journal of oral pathology & medicine》2019,48(1):3-9
Fibrous dysplasia is a non‐neoplastic developmental process that affects the craniofacial bones, characterized by painless enlargement as a result of bone substitution by abnormal fibrous tissue. Postzygotic somatic activating mutations in the GNAS1 gene cause fibrous dysplasia and have been extensively investigated, as well as being helpful in the differential diagnosis of the disease. Fibrous dysplasia may involve one (monostotic) or multiple bones (polyostotic), sporadically or in association with McCune‐Albright syndrome, Jeffe‐Lichenstein syndrome, or Mazabreud syndrome. This review summarizes the current knowledge on fibrous dysplasia, emphasizing the value of integrating the understanding of its molecular pathogenesis with the clinical, radiological, and histopathological features. In addition, we address important aspects related to the differential diagnosis and patient management. 相似文献
6.
de Oliveira Adilson J M Solla Davi J. F. de Oliveira Klever F. Amaral Bruno S. Andrade Almir F. Kolias Angelos G. Paiva Wellingson S. 《Neurological sciences》2022,43(1):427-434
Neurological Sciences - Chronic subdural haematoma (CSDH) is one of the most common neurosurgical pathologies. The recurrence of chronic subdural haematomas is an important concern, considering... 相似文献
7.
8.
A C Da Rosa B Kemp T Paiva F H Lopes da Silva H A Kamphuisen 《Electroencephalography and clinical neurophysiology》1991,78(1):71-79
A model of sleep phasic events such as vertex waves, K complexes, delta waves and sleep spindles is proposed. It consists of feedback loops that are driven by white noise (simulating tonic delta and sigma activity) and by isolated random impulses, simulating vertex waves or K complexes, depending on the background tonic activity. A model-based method for the detection of sleep phasic events was implemented in a personal computer. Its performance was investigated using simulated and real whole-night EEG signals. The method was able to detect K complexes and vertex waves in a reliable way in spite of their variable shapes and in the presence of a variety of background activities. The detector appears to have superior performance to those so far reported in the literature. The performance of the detector was also compared to that of an electroencephalographer using normal sleep EEG records of 8 h duration from 6 subjects. The performance was satisfactory both in terms of accuracy and reliability. The problem of detecting K complexes in stages 3 and 4 of sleep is discussed. 相似文献
9.
10.
Marcin Wojnar Dariusz Wasilewski Halina Matsumoto Artur Cedro 《Alcoholism, clinical and experimental research》1997,21(8):1351-1355
A retrospective study compared the course of alcohol withdrawal, including delirium tremens, in women and men hospitalized in the Nowowiejski Hospital in Warsaw from 1973 to 1987. Medical records pertaining to 1179 patients were analyzed; 13.8% of these patients were women and 86.2% were men. The study showed that women began intensive alcohol drinking later than men ( p < 0.0001), but the period between the onset of alcohol abuse and the first occurrence of alcohol withdrawal was shorter in women than in men ( p < 0.0001). In the period of heavy drinking before hospitalization, women consumed significantly less alcohol then men ( p < 0.0001); moreover, women drank nonbeverage alcohol less frequently than men ( p < 0.05). Women were hospitalized substantially longer than men ( p < 0.0001), whereas the duration of alcohol withdrawal symptoms at the time of hospitalization was comparable in both groups. Withdrawal seizures were significantly more frequent among men than among women ( p < 0.001). Significant differences in the patients'somatic conditions were not noted between the groups, with the exception of anemia and decreased potassium concentration, which were more frequently observed in women (both p < 0.0001), and of increased concentration of ALT and hypoproteinemia, which were more frequent in men (respectively, p < 0.05 and p < 0.01). Co-existing personality disorders, depressive disorders, and anxiety disorders—as well as abuse of benzodiazepines and barbiturates—were more frequently observed in women ( p < 0.0001). The period between the first hospitalization due to alcohol withdrawal and the time of death was significantly shorter in men than in women ( p < 0.05). The results point to differences in the conditions and the course of alcohol dependence and alcohol withdrawal between women and men. 相似文献