排序方式: 共有3条查询结果,搜索用时 15 毫秒
1
1.
The effects of the attributable fraction and the duration of symptoms on burden estimates of influenza‐associated respiratory illnesses in a high HIV prevalence setting,South Africa, 2013‐2015
下载免费PDF全文
![点击此处可从《Influenza and other respiratory viruses》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Stefano Tempia Sibongile Walaza Jocelyn Moyes Adam L. Cohen Claire von Mollendorf Meredith L. McMorrow Sarona Mhlanga Florette K. Treurnicht Marietjie Venter Marthi Pretorius Orienka Hellferscee Nicole Wolter Anne von Gottberg Arthemon Nguweneza Johanna M. McAnerney Halima Dawood Ebrahim Variava Shabir A. Madhi Cheryl Cohen 《Influenza and other respiratory viruses》2018,12(3):360-373
Background
The attributable fraction of influenza virus detection to illness (INF‐AF) and the duration of symptoms as a surveillance inclusion criterion could potentially have substantial effects on influenza disease burden estimates.Methods
We estimated rates of influenza‐associated influenza‐like illness (ILI) and severe acute (SARI‐10) or chronic (SCRI‐10) respiratory illness (using a symptom duration cutoff of ≤10 days) among HIV‐infected and HIV‐uninfected patients attending 3 hospitals and 2 affiliated clinics in South Africa during 2013‐2015. We calculated the unadjusted and INF‐AF‐adjusted rates and relative risk (RR) due to HIV infection. Rates were expressed per 100 000 population.Results
The estimated mean annual unadjusted rates of influenza‐associated illness were 1467.7, 50.3, and 27.4 among patients with ILI, SARI‐10, and SCRI‐10, respectively. After adjusting for the INF‐AF, the percent reduction in the estimated rates was 8.9% (rate: 1336.9), 11.0% (rate: 44.8), and 16.3% (rate: 22.9) among patients with ILI, SARI‐10, and SCRI‐10, respectively. HIV‐infected compared to HIV‐uninfected individuals experienced a 2.3 (95% CI: 2.2‐2.4)‐, 9.7 (95% CI: 8.0‐11.8)‐, and 10.0 (95% CI: 7.9‐12.7)‐fold increased risk of influenza‐associated illness among patients with ILI, SARI‐10, and SCRI‐10, respectively. Overall 34% of the estimated influenza‐associated hospitalizations had symptom duration of >10 days; 8% and 44% among individuals aged <5 and ≥5 years, respectively.Conclusion
The marginal differences between unadjusted and INF‐AF‐adjusted rates are unlikely to affect policies on prioritization of interventions. HIV‐infected individuals experienced an increased risk of influenza‐associated illness and may benefit more from annual influenza immunization. The use of a symptom duration cutoff of ≤10 days may underestimate influenza‐associated disease burden, especially in older individuals. 相似文献2.
Stefano Tempia Jocelyn Moyes Adam L. Cohen Sibongile Walaza Ijeoma Edoka Meredith L. McMorrow Florette K. Treurnicht Orienka Hellferscee Nicole Wolter Anne von Gottberg Athermon Nguweneza Johanna M. McAnerney Halima Dawood Ebrahim Variava Cheryl Cohen 《Influenza and other respiratory viruses》2019,13(5):484-495
3.
1