全文获取类型
收费全文 | 2862篇 |
免费 | 366篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 82篇 |
妇产科学 | 292篇 |
基础医学 | 287篇 |
口腔科学 | 129篇 |
临床医学 | 941篇 |
内科学 | 410篇 |
皮肤病学 | 72篇 |
神经病学 | 131篇 |
特种医学 | 247篇 |
外科学 | 176篇 |
综合类 | 58篇 |
预防医学 | 190篇 |
眼科学 | 21篇 |
药学 | 104篇 |
中国医学 | 7篇 |
肿瘤学 | 85篇 |
出版年
2023年 | 53篇 |
2022年 | 23篇 |
2021年 | 46篇 |
2020年 | 53篇 |
2019年 | 56篇 |
2018年 | 85篇 |
2017年 | 109篇 |
2016年 | 106篇 |
2015年 | 126篇 |
2014年 | 133篇 |
2013年 | 154篇 |
2012年 | 122篇 |
2011年 | 134篇 |
2010年 | 139篇 |
2009年 | 144篇 |
2008年 | 100篇 |
2007年 | 107篇 |
2006年 | 93篇 |
2005年 | 69篇 |
2004年 | 69篇 |
2003年 | 82篇 |
2002年 | 59篇 |
2001年 | 73篇 |
2000年 | 47篇 |
1999年 | 81篇 |
1998年 | 103篇 |
1997年 | 117篇 |
1996年 | 114篇 |
1995年 | 99篇 |
1994年 | 68篇 |
1993年 | 51篇 |
1992年 | 33篇 |
1991年 | 38篇 |
1990年 | 18篇 |
1989年 | 40篇 |
1988年 | 36篇 |
1987年 | 20篇 |
1986年 | 30篇 |
1985年 | 36篇 |
1984年 | 14篇 |
1983年 | 14篇 |
1982年 | 20篇 |
1981年 | 14篇 |
1980年 | 18篇 |
1979年 | 9篇 |
1978年 | 20篇 |
1977年 | 20篇 |
1976年 | 18篇 |
1975年 | 18篇 |
1967年 | 3篇 |
排序方式: 共有3250条查询结果,搜索用时 15 毫秒
1.
2.
3.
Rubens Souza de OLIVEIRA Lanna Jamile Corrêa da COSTA Fernanda Atanaena Gon?alves de ANDRADE Wilson UIEDA Luzia Fátima Alves MARTORELLI Ana Paula de Arruda Geraldes KATAOKA Elizabeth Salbé Travassos da ROSA Pedro Fernando da Costa VASCONCELOS Armando de Souza PEREIRA Ant?nio Ismael Barros do CARMO Marcus Emanuel Barroncas FERNANDES 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(6):497-503
The outbreaks of rabies in humans transmitted by Desmodus rotundus in 2004 and 2005,
in the northeast of the Brazilian State of Para, eastern Amazon basin, made this a
priority area for studies on this zoonosis. Given this, the present study provides
data on this phenomenon in an urban context, in order to assess the possible
circulation of the classic rabies virus (RABV) among bat species in Capanema, a town
in the Amazon basin. Bats were collected, in 2011, with mist nets during the wet and
dry seasons. Samples of brain tissue and blood were collected for virological and
serological survey, respectively. None of the 153 brain tissue samples analyzed
tested positive for RABV infection, but 50.34% (95% CI: 45.67-55.01%) of the serum
samples analyzed were seropositive. Artibeus planirostris was the most common
species, with a high percentage of seropositive individuals (52.46%, 95% CI: 52.31
52.60%). Statistically, equal proportions of seropositive results were obtained in
the rainy and dry seasons (c2 = 0.057, d.f. = 1, p = 0.88). Significantly
higher proportions of males (55.96%, 95% CI: 48.96-62.96%) and adults (52.37%, 95%
CI: 47.35-57.39%) were seropositive. While none of the brain tissue samples tested
positive for infection, the high proportion of seropositive specimens indicates that
RABV may be widespread in this urban area. 相似文献
4.
D Van Neste† RM Trüeb‡ 《Journal of the European Academy of Dermatology and Venereology》2006,20(5):578-583
BACKGROUND: Computer-assisted image analysis has been proposed for human hair growth studies. METHODS: The performances of Trichoscan, a commercially available automated system combining epiluminiscence microscopy with digital image analysis, developed for office-based hair growth measurements, have been evaluated comparatively on the same skin sites using standardized photographic equipment and calibrated processing for contrast-enhanced phototrichogram (CE-PTG) analysis. This reference method has been validated with scalp biopsies and histological examination of serial sectioning. RESULTS: Besides edge effects, hair fibres escaped the Trichoscan analysis for various reasons including, but not limited to, thickness, pigmentation, closeness and crossing. CONCLUSION: Most of these problems have been identified in the late 1980s and remain largely unsolved by the processing software that was evaluated in 2004. Therefore claims promoting the Trichoscan method for accurate hair measurements in clinical trials on scalp and body hair are not supported by the present investigation. The speed at which the analysis is performed is outweighed by the errors in signal detection. Therefore we suggest that improvements must be clearly documented before Trichoscan is established for quantified diagnostic purposes and detailed hair cycle monitoring during hair trials. 相似文献
5.
C G Arruda J M Aldrighi L A Bortolotto I N Alecrin J A F Ramires 《Gynecological endocrinology》2006,22(10):557-563
BACKGROUND: Arterial hypertension and postmenopausal reduction of estrogen levels may be involved in modifications of the stiffness of large arteries. OBJECTIVES: To evaluate the pulse-wave velocity (PWV) and indirectly the arterial stiffness in hypertensive postmenopausal women submitted to hormone therapy with estradiol alone or combined with norethisterone acetate. SUBJECTS: Forty-five hypertensive postmenopausal women were double-blindly, randomly assigned to three arms of treatment: placebo (group I); estradiol 2 mg/day (group II); or estradiol 2 mg/day and norethisterone acetate 1 mg/day (group III). METHODS: Arterial stiffness was assessed from PWV measurements of the common carotid and femoral arteries (CF-PWV) and the common carotid and radial arteries (CR-PWV) obtained using the automatic Complior(R) device, taken at baseline and after 12 weeks of treatment. RESULTS: After the 12-week treatment, values of CF-PWV and CR-PWV were not significantly different (p = 0.910 and p = 0.736, respectively) among the groups. Systolic blood pressure showed a positive correlation with CF-PWV in groups II and III (p = 0.02 and p < 0.001, respectively). CONCLUSIONS: PWV and arterial stiffness in postmenopausal hypertensive women did not reduce over a 12-week treatment with estradiol alone compared with the same period of treatment with estradiol combined with norethisterone acetate. 相似文献
6.
7.
V Schleyer† S Radakovic-Fijan‡ S Karrer† T Zwingers§ A Tanew‡ M Landthaler† RM Szeimies† 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):823-828
BACKGROUND: Based on good results in the treatment of superficial skin tumours, since the early 1990s topical photodynamic therapy with aminolaevulinic acid (ALA PDT) has been used for disseminated, inflammatory dermatoses including psoriasis. However, there is still a lack of well-documented trials. OBJECTIVE: A prospective randomized, double-blind phase I/II intrapatient comparison study was conducted in 12 patients to investigate whether topical ALA PDT is an effective treatment for chronic plaque-type psoriasis. METHODS: In each patient three psoriatic plaques were randomly treated with a light dose of 20 J/cm(2) and 0.1%, 1% and 5% ALA, respectively. Treatment was conducted twice a week until complete clearance or for a maximum of 12 irradiations. Therapeutic efficacy was assessed by weekly determination of the psoriasis severity index (PSI). RESULTS: The mean percentage improvement was 37.5%, 45.6% and 51.2% in the 0.1%, 1% and 5% ALA-treated groups, respectively. Irradiation had to be interrupted several times because of severe burning and pain sensation. CONCLUSION: Topical ALA PDT did not prove to be an appropriate treatment option for plaque-type psoriasis due to disappointing clinical efficacy, the time-consuming treatment procedure and its unfavourable adverse event profile. 相似文献
8.
9.
10.