全文获取类型
收费全文 | 1554篇 |
免费 | 80篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 118篇 |
妇产科学 | 52篇 |
基础医学 | 246篇 |
口腔科学 | 37篇 |
临床医学 | 120篇 |
内科学 | 306篇 |
皮肤病学 | 84篇 |
神经病学 | 91篇 |
特种医学 | 27篇 |
外科学 | 108篇 |
综合类 | 15篇 |
预防医学 | 122篇 |
眼科学 | 68篇 |
药学 | 130篇 |
中国医学 | 20篇 |
肿瘤学 | 85篇 |
出版年
2024年 | 1篇 |
2023年 | 20篇 |
2022年 | 28篇 |
2021年 | 55篇 |
2020年 | 37篇 |
2019年 | 55篇 |
2018年 | 73篇 |
2017年 | 50篇 |
2016年 | 57篇 |
2015年 | 60篇 |
2014年 | 94篇 |
2013年 | 103篇 |
2012年 | 166篇 |
2011年 | 141篇 |
2010年 | 74篇 |
2009年 | 62篇 |
2008年 | 110篇 |
2007年 | 57篇 |
2006年 | 77篇 |
2005年 | 70篇 |
2004年 | 64篇 |
2003年 | 58篇 |
2002年 | 43篇 |
2001年 | 7篇 |
2000年 | 6篇 |
1999年 | 5篇 |
1998年 | 6篇 |
1997年 | 7篇 |
1996年 | 9篇 |
1995年 | 4篇 |
1994年 | 8篇 |
1993年 | 5篇 |
1992年 | 2篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 6篇 |
1986年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1975年 | 1篇 |
1972年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有1638条查询结果,搜索用时 15 毫秒
1.
Drishty Satpati Ketaki Bapat Archana Mukherjee Sharmila Banerjee Kanchan Kothari Meera Venkatesh 《Applied radiation and isotopes》2006,64(8):888-892
Studies on the development of imaging agents for targeting neuroreceptors is an area of considerable interest owing to the limited availability of specific as well as selective radiolabeled agents. Therefore, with an aim of developing a receptor-specific agent, iminodiacetic acid (IDA) derivative of 5-hydroxy tryptamine viz., HTIDA has been synthesized. HTIDA could be radiolabeled with the synthon [(99m)Tc(CO)(3)(H(2)O)(3)](+) in >98% yield. The biodistribution studies in normal Swiss mice showed that the (99m)Tc(CO)(3)-HTIDA crosses the blood-brain barrier successfully with a brain uptake of 0.5%ID/g at 5min post injection. The other relevant observations from biodistribution studies included no significant uptake in any other organ and fast clearance from blood, lungs and liver. 相似文献
2.
Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. The epidemiology of ESBL-producing K. pneumoniae, the mechanisms of resistance, and treatment strategies for infections caused by these organisms are reviewed. 相似文献
3.
4.
Kalpana Agarwal Anita Mukherjee Archana Sharma Ramesh Sharma Kuldip Raj Bhardwaj Soumitra Sen 《Environmental and molecular mutagenesis》1992,19(4):323-326
Fenfluramine, an amphetamine derivative used in the treatment of obesity, has been evaluated in vivo in the bone marrow cells of Swiss albino mice using two cytogenetic endpoints for assessing its genotoxic and clastogenic potentials. Concentrations of 0.75, 1.5, 3.0, and 5.0 mg/kg b.w. were administered orally for the study of sister chromatid exchange frequencies and chromosome aberrations (CA). SCE frequencies showed a positive dose response; 1.5 mg/kg being the minimum effective concentration. Fen caused a prolongation of cell cycle at all concentrations. Except for the minimum therapeutic dose (0.75 mg), all other doses (1.5, 3.0, and 5.0 mg) showed a significant increase in the percentage of damaged cells over that of the vehicle control. The degree of clastogenicity was directly proportional to the dosage used and inversely related with the duration of treatment. A gradual reduction of the clastogenic potential was observed after 12 and 24 hr of exposure, indicating that the maximum effect occurs at the middle or late synthetic phase of the cell cycle. This study, probably the first detailed screening of the drug for its genotoxicity, shows that Fen is moderately clastogenic and a DNA damaging agent in vivo. 相似文献
5.
Sturge-Weber syndrome is a rare neurocutaneous disorder characterized by a facial nevus flammeus and extensive angiomatous changes involving the leptomeninges, the dura, and vessels of the gray and white matter. Oculodermal melanocytosis is characterized by hyperpigmentation of the facial skin in the distribution of the ophthalmic, maxillary, and occasionally mandibular division of the trigeminal nerve. 相似文献
6.
7.
Clarissa A. Shavers Alytia A. Levendosky Stacie M. Dubay Archana Basu Johanna Jenei 《Journal of Applied Biobehavioral Research》2005,10(1):27-38
Presently, in our society, thousands of children, adolescents, and adults are physically, mentally, and emotionally traumatized from exposure to domestic violence (DV). Exposure to DV, defined here as male violence against their female partners, occurs among all ethnic, cultural, socioeconomic, geographical, and racial groups. DV can lead to depression, negative self‐esteem, and general psychological distress in women. Children exposed to DV have an increased risk of behavioral, emotional, and social problems. DV shelters often provide group counseling and support services for battered women, children, and adolescents residing there, but the programs do not reach the majority of women living in the broader community. Furthermore, few studies have examined the effectiveness and efficacy of support group treatment intervention programs for battered women and children. This is due, in part, to the methodological difficulties inherent in this design. As a way to meet the needs of families that have experienced DV, academic researchers from a Midwestern university and a director of counseling services from a local domestic violence agency have partnered to offer a psycho‐educational intervention designed to 相似文献
8.
9.
10.
Although there are ever increasing reports of extraintestinal human infections caused by Aeromonads, in both immunocompromised and immunocompetent patients, respiratory tract infections remain uncommon. We describe a case of aspiration pneumonia in an immunocompetent patient with multiple sclerosis, caused by a community acquired, multidrug resistant strain of Aeromonas hydrophila sensitive only to meropenem. The case highlights the clinical significance of Aeromonas hydrophila as a respiratory pathogen, as well as the community origin of multidrug resistance and the utility of newer carbapenems in such cases. 相似文献