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1.
Osteoblast adhesion on biomaterials 总被引:118,自引:0,他引:118
Anselme K 《Biomaterials》2000,21(7):667-681
The development of tissue engineering in the field of orthopaedic surgery is now booming. Two fields of research in particular are emerging: the association of osteo-inductive factors with implantable materials; and the association of osteogenic stem cells with these materials (hybrid materials). In both cases, an understanding of the phenomena of cell adhesion and, in particular, understanding of the proteins involved in osteoblast adhesion on contact with the materials is of crucial importance. The proteins involved in osteoblast adhesion are described in this review (extracellular matrix proteins, cytoskeletal proteins, integrins, cadherins, etc.). During osteoblast/material interactions, their expression is modified according to the surface characteristics of materials. Their involvement in osteoblastic response to mechanical stimulation highlights the significance of taking them into consideration during development of future biomaterials. Finally, an understanding of the proteins involved in osteoblast adhesion opens up new possibilities for the grafting of these proteins (or synthesized peptide) onto vector materials, to increase their in vivo bioactivity or to promote cell integration within the vector material during the development of hybrid materials. 相似文献
2.
F. Anselme K. Collomp B. Mercier S. Ahmaïdi Ch. Prefaut 《European journal of applied physiology》1992,65(2):188-191
Summary The aim of this study was to specify the effects of caffeine on maximal anaerobic power (W
max). A group of 14 subjects ingested caffeine (250 mg) or placebo in random double-blind order. TheW
max was determined using a force-velocity exercise test. In addition, we measured blood lactate concentration for each load at the end of pedalling and after 5 min of recovery. We observed that caffeine increasedW
max [964 (SEM 65.77) W with caffeine vs 903.7 (SEM 52.62) W with placebo;P<0.02] and blood lactate concentration both at the end of pedalling [8.36 (SEM 0.95) mmol · l–1 with caffeine vs 7.17 (SEM 0.53) mmol · l–1 with placebo;P<0.011 and after 5 min of recovery [10.23 (SEM 0.97) mmol · l–1 with caffeine vs 8.35 (SEM 0.66) mmol · l–1 with placebo;P<0.04]. The quotient lactate concentration/power (mmol · l–1 · W–1) also increased with caffeine at the end of pedalling [7.6 · 10–3 (SEM 3.82 · 10–5) vs 6.85 · 10–3 (SEM 3.01 · 10–5);P<0.01] and after 5 min of recovery [9.82·10–3 (SEM 4.28 · 10–5) vs 8.84 · 10–3 (SEM 3.58 · 10–5);P<0.02]. We concluded that caffeine increased bothW
max and blood lactate concentration. 相似文献
3.
Anselme Millogo Ahmed Loukil Coralie LOllivier Diakourga Arthur Djibougou Sylvain Godreuil Michel Drancourt 《Emerging infectious diseases》2021,27(6):1758
Mycobacterium leprae was detected by optical microscopy, fluorescent in situ hybridization, and molecular detection in feces collected for the diagnosis of Entamoeba coli enteritis in a leprosy patient in Burkina Faso. This observation raises questions about the role of fecal excretion of M. leprae in the natural history and diagnosis of leprosy. 相似文献
4.
Carolina Degen Meotti Glaura Plates Letycia Lopes Chagas Nogueira Renata Anselme da Silva Karoline Silva Paolini Elias Moreira Nunes Fred Bernardes Filho 《Anais brasileiros de dermatologia》2014,89(2):332-333
Cutaneous larva migrans is a pruritic dermatitis due to the inoculation of helminths
larvae in the skin, and it often occurs in children in tropical and subtropical
areas. The authors describe an atypical case of cutaneous larva migrans in a 11
year-old child with scalp involvement, an unusual topography for this lesion. 相似文献
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Hervé Poty Frederic Anselme Nadir Saoudi 《Journal of interventional cardiac electrophysiology》1997,2(1):57-69
Background: Until recently no clinical studies had reported precise right atrium (RA) mapping when performing induction of atrial flutter (AFI). We studied the mode of tachycardia initiation in 16 patients (pts) referred for radiofrequency (RF) AFl ablation. AFl induction was performed at the beginning of the procedure (n = 10), or after previous AFl termination during RF delivery (n = 6). Detailed analysis of AFl initiation was provided by duodecapolar (Halo) and multipolar catheters positioned in the peritricuspidian region at the lateral right atrial wall (LRA), the inferior vena cavatricuspid annulus (IVC-TA) isthmus and the interatrial septum. Induction was obtained during incremental pacing (IAP) (15 pts) or programmed stimulation (1 pt) from the proximal coronary sinus (PCS).Results: Atrial flutter with counterclockwise (CCW) RA rotation was induced in all pts by PCS pacing. During PCS IAP, at long pacing cycle lengths, impulse propagated in a clockwise (CW) direction through the IVC-TA isthmus and then upward at low (L) LRA. This led to a collision at the mid LRA with another wave front propagating in a CCW direction at the septum. IAP from PCS induced a progressive delay of propagation at the IVC-TA isthmus resulting in a prolongation of the PCS-Mid Isthmus interval from 85±29 to 151±42 msec. At same pacing cycle lengths (CL), the PCS-HLRA interval was comparatively less prolonged, from 75±12 to 105±18 msec, p = 0.0007. This preferential slowing of conduction between PCS and mid isthmus, during IAP from PCS, was associated with a displacement of the zone of collision to the Low LRA. Finally a CW functional block occurred at the IVC-TA isthmus and CCW AFl was induced through a period of transient concealed entrainment. The paced CL required to initiate flutter ranged from 290 to 180 msec and the mean CL of induced atrial flutter was 254±27 msec.Conclusions: The IVC-TA isthmus has decremental properties and exhibits wenckebach phenomenon during incremental PCS pacing. Initiation of a counterclockwise flutter by PCS pacing is associated with appearance of a functional unidirectional block at the IVC-TA isthmus. 相似文献
7.
Jessica Viviana Hinostroza Ramos Karine Anselme Anglique Simon-Masseron Lydie Ploux 《RSC advances》2018,8(44):25112
The usual sources of phosphorus for metal phosphates are obtained from phosphate rocks, of which resources are depleted. As a substitute for these mineral sources, an original method of synthesis has been developed to prepare macroporous zinc phosphates using casein phosphoprotein. This bio-sourced reactant plays during the synthesis the roles of both a phosphorus source and a reducing agent for silver nanoparticles. Thus, zinc phosphates loaded with different Ag contents (up to 6.4 wt%) are prepared via hydrothermal treatment at 100 °C. Silver nanoparticles co-crystallized with hopeite, Zn3(PO4)2 and/or Zn2P2O7. In addition, casein induces porosity within the zinc phosphate framework and provides macropores (diameter of >50 nm) during calcination. The antibacterial properties against Escherichia coli K12 bacteria of Ag-containing and Ag-free porous zinc phosphates (calcined at 750 °C) were also tested for the first time.Phosphoproteins as key reactants in an original method of synthesis of silver-doped macroporous zinc phosphates with antibacterial properties. 相似文献
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