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Jean Reignier Michael Darmon Romain Sonneville Anne-Laure Borel Maité Garrouste-Orgeas Stéphane Ruckly Bertrand Souweine Anne-Sylvie Dumenil Hakim Haouache Christophe Adrie Laurent Argaud Lilia Soufir Guillaume Marcotte Virginie Laurent Dany Goldgran-Toledano Christophe Clec’h Carole Schwebel Elie Azoulay Jean-François Timsit 《Intensive care medicine》2015,41(5):875-886
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Clinical and ultrasonographic correlations following three surgical anti-incontinence procedures (TOT,TVT and TVT-O) 总被引:1,自引:1,他引:0
Gautier Chene Benjamin Cotte Anne-Sylvie Tardieu Denis Savary Aslam Mansoor 《International urogynecology journal》2008,19(8):1125-1131
The aim of this study was to compare ultrasonographic findings on tape position, angulation and mobility following three surgical anti-incontinence procedures (trans-obturator tape (TOT), tension-free vaginal tape (TVT), tension-free vaginal tape obturator (TVT-O)) and to correlate these data with clinical signs of cures and failures and de novo voiding disorders. In this prospective study, vesicourethral static and dynamic analysis of 81 patients (30 TOT, 28 TVT, 23 TVT-O) were evaluated using introital ultrasonography. Width, position and appearance of the tape were similar in all three groups, i.e. like a "V" at rest, round angulation on Valsalva and closed angulation at maximum retaining. Moreover, closer angulation on Valsalva was associated with voiding disorders. Closer angulation at retaining was associated with de novo urge incontinence. Larger angulation of the tape at rest appeared to be significantly associated with recurrent stress incontinence. Ultrasonography could a be useful tool assessing anti-incontinence procedures and investigating post-operative voiding disorders. 相似文献
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Thirteen saponins were isolated and identified from Calendula officinalis, C. arvensis and Hedera helix. Mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the Salmonella/microsomal assay. The Salmonella tester strain TA98 +/- S9 mix was used. Screening of the antimutagenic activity was performed with a known promutagen: benzo-[a]pyrene (BaP) and a mutagenic urine concentrate from a smoker (SU). Antimutagenic activities were also compared with the activity of chlorophyllin. All the saponins were found to be non-toxic and non-mutagenic for doses of 400 micrograms. Chlorophyllin inhibited the mutagenic activities of BaP (1 microgram) and SU (5 microliters) in a dose-dependent manner. The four saponins from C. arvensis and the three saponins from H. helix showed antimutagenic activity against BaP (1 microgram) and SU (5 microliters) with a dose-response relationship. The possible mechanism of the antimutagenic activity of saponins is discussed. 相似文献