全文获取类型
收费全文 | 4432篇 |
免费 | 334篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 42篇 |
儿科学 | 85篇 |
妇产科学 | 99篇 |
基础医学 | 791篇 |
口腔科学 | 47篇 |
临床医学 | 464篇 |
内科学 | 913篇 |
皮肤病学 | 44篇 |
神经病学 | 307篇 |
特种医学 | 162篇 |
外科学 | 905篇 |
综合类 | 30篇 |
一般理论 | 1篇 |
预防医学 | 242篇 |
眼科学 | 194篇 |
药学 | 202篇 |
中国医学 | 9篇 |
肿瘤学 | 244篇 |
出版年
2022年 | 33篇 |
2021年 | 114篇 |
2020年 | 62篇 |
2019年 | 64篇 |
2018年 | 92篇 |
2017年 | 64篇 |
2016年 | 73篇 |
2015年 | 66篇 |
2014年 | 108篇 |
2013年 | 167篇 |
2012年 | 222篇 |
2011年 | 216篇 |
2010年 | 116篇 |
2009年 | 120篇 |
2008年 | 205篇 |
2007年 | 200篇 |
2006年 | 198篇 |
2005年 | 174篇 |
2004年 | 180篇 |
2003年 | 148篇 |
2002年 | 147篇 |
2001年 | 125篇 |
2000年 | 117篇 |
1999年 | 116篇 |
1998年 | 54篇 |
1997年 | 37篇 |
1996年 | 42篇 |
1995年 | 37篇 |
1994年 | 50篇 |
1993年 | 42篇 |
1992年 | 129篇 |
1991年 | 103篇 |
1990年 | 109篇 |
1989年 | 100篇 |
1988年 | 77篇 |
1987年 | 81篇 |
1986年 | 63篇 |
1985年 | 59篇 |
1984年 | 68篇 |
1983年 | 49篇 |
1982年 | 38篇 |
1981年 | 29篇 |
1980年 | 30篇 |
1979年 | 35篇 |
1977年 | 40篇 |
1976年 | 26篇 |
1974年 | 27篇 |
1973年 | 48篇 |
1972年 | 34篇 |
1971年 | 27篇 |
排序方式: 共有4781条查询结果,搜索用时 15 毫秒
1.
Anne-Sophie Worm Fenger Markus Harboe Olsen Maria Louise Fabritius Christian Gunge Riberholt Kirsten Møller 《Acta anaesthesiologica Scandinavica》2023,67(2):240-247
Background
Hyperglycaemia is common in patients with acute brain injury admitted to an intensive care unit (ICU). Many studies have found associations between development of hyperglycaemia and increased mortality in hospitalised patients. However, the optimal target for blood glucose control is unknown. We want to conduct a systematic review with meta-analysis and trial sequential analysis to explore the beneficial and harmful effects of restrictive versus liberal glucose control on patient outcomes in adults with severe acute brain injury.Methods
We will systematically search medical databases including CENTRAL, Embase, MEDLINE and trial registries. We will search the following websites for ongoing or unpublished trials: http://www.controlled-trials.com/ , http://www.clinicaltrials.gov/ , www.eudraCT.com , http://centerwatch.com/ , The Cochrane Library's CENTRAL, PubMed, EMBASE, Science Citation Index Expanded and CINAHL. Two authors will independently review and select trials and extract data. We will include randomised trials comparing levels of glucose control in our analyses and observational studies will be included to address potential harms. The primary outcomes are defined as all-cause mortality, functional outcome and health-related quality of life. Secondary outcomes include serious adverse events including hypoglycaemia, length of ICU stay and duration of mechanical ventilation, and explorative outcomes including intracranial pressure and infection. Trial Sequential Analysis will be used to investigate the risk of type I error due to repetitive testing and to further explore imprecision. Quality of trials will be evaluated using the Cochrane Risk of Bias tool, and quality of evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach.Discussion
The results of the systematic review will be disseminated through peer-reviewed publication. With the review, we hope to inform future randomised clinical trials and improve clinical practice. 相似文献2.
3.
4.
5.
Thomas Donohue Morton J. Kern Richard Bach Frank Aguirre Thomas Wolford 《Catheterization and cardiovascular interventions》1993,28(2):155-161
The vasomotor response of native human collateral vessels to pharmacologic or hemodynamic vasodilatory stimuli is not well known. We describe a case where retrograde collateral flow velocity was measured both at baseline and following selected hemodynamic and pharmacologic interventions. This index case represents the first in a series of potential human physiologic studies designed to address questions pertaining to control of collateral blood supply in humans. © 1993 Wiley-Liss, Inc. 相似文献
6.
7.
Mohammed E Abushaiqa Frank K Zaran David S Bach Richard T Smolarek Margo S Farber 《American journal of health-system pharmacy》2007,64(11):1170-1173
PURPOSE: Educational interventions to reduce the use of abbreviations and dosage designations that were deemed unsafe at a level 1 trauma center are described. SUMMARY: Strategies to reduce the use of unsafe abbreviations at Detroit Receiving Hospital were studied. Six abbreviations and dosage designations were deemed as unsafe by the site's medication-use and patient medical safety committees: (1) U for units, (2) microg for microgram, (3) TIW for three times a week, (4) the degree symbol for hour, (5) trailing zeros after a decimal point, and (6) the lack of leading zeros before a decimal point. Data on abbreviation use was collected starting in September 2003 by examining copies of patients' order sheets, which are sent from nursing units to the pharmacy for processing. Data were collected during three 24-hour periods each month, with 7-10 days between each period. A data collection sheet was developed to assist in documenting the number of opportunities for each unsafe abbreviation and the actual incidence of each. Educational strategies were developed and implemented starting in October 2003 to decrease the use of the unsafe abbreviations. These strategies included inservice education programs for the medical, pharmacy, and nursing staffs; laminated pocket cards; patient chart dividers; stickers; and interventions by pharmacists and nurses during medication prescribing. During the eight-month evaluation period, 20,160 orders were reviewed, representing 27,663 opportunities to use a designated unsafe abbreviation. Educational interventions successfully reduced the overall incidence of unsafe abbreviations from 19.69% to 3.31%. CONCLUSION: Educational interventions markedly reduced the use of unsafe abbreviations in medication orders over an eight-month evaluation period. 相似文献
8.
Painful polyneuropathy is a common neuropathic pain condition. The present study describes health-related quality of life (HRQL) in a sample of patients with painful polyneuropathy of different origin and the possible predictive role of HRQL for analgesic effect. Ninety-three patients with a diagnosis of painful polyneuropathy were included in the analysis. Data were obtained from three randomised, placebo-controlled cross-over studies testing the effect of different drugs on polyneuropathic pain (St. John's wort, venlafaxine/imipramine and valproic acid). Patients completed a HRQL questionnaire (SF-36) after a drug-free baseline period and at the end of each treatment period. At baseline, all eight SF-36 scores were lower than in the normal population. No significant differences were found between SF-36 scales during placebo and treatment with valproic acid and St. John's wort. Those two drugs had not shown a pain relieving effect in former analysis. The SF-36 scale of bodily pain (BP) was improved by venlafaxine treatment (p=0.023). General health (GH) and vitality (VT) were improved under treatment with imipramine (GH: p=0.006, VT: p=0.015). In a multivariate logistic regression analysis, baseline SF-36 scores predicted subsequent response to pharmacological treatment. Results show an impaired HRQL in painful polyneuropathy and suggest that HRQL may predict response to analgesic treatment. 相似文献
9.
10.
Michael Bach Graham E. Holder 《Documenta ophthalmologica. Advances in ophthalmology》1996,92(3):193-202
The pattern electroretinogram was recorded to checkerboard stimuli with a wide range of check sizes and two stimulus field
sizes. Check sizes ranged from 0.25° to 7° (field size, 16°×14°) and 0.25° to 15° (field size, 32°×27°) in 14 and seven subjects,
respectively. Reversal rate was 4.5/s. For minimal intrusion of blink artifacts the interrupted stimulation technique was
employed. The P50 and N95 components of the pattern electroretinogram were evaluated separately. With both stimulus field
sizes amplitude of P50 and N95 was maximal between 0.75° and 1°. With smaller check sizes the amplitude dropped monotonically.
With larger check sizes field size played a role: with the 16°×14° field, P50 gradually dropped to 89% from 1° to 7°, which
was paralleled by N95 only up to 7°, where N95 dropped to 81% (p<0.05). With the 32°×27° field, there was no significant difference in size dependency between P50 and N95 for large checks,
both components staying constant from 1° to 15° We conclude that there is only minor large-check attenuation of the pattern
electroretinogram, especially with a large field. The apparent field-size dependency may explain previous discrepancies in
the literature. 相似文献