全文获取类型
收费全文 | 22508篇 |
免费 | 1862篇 |
国内免费 | 92篇 |
专业分类
耳鼻咽喉 | 195篇 |
儿科学 | 771篇 |
妇产科学 | 739篇 |
基础医学 | 3009篇 |
口腔科学 | 477篇 |
临床医学 | 2712篇 |
内科学 | 4329篇 |
皮肤病学 | 327篇 |
神经病学 | 2147篇 |
特种医学 | 489篇 |
外科学 | 2732篇 |
综合类 | 273篇 |
一般理论 | 30篇 |
预防医学 | 2310篇 |
眼科学 | 465篇 |
药学 | 1410篇 |
中国医学 | 58篇 |
肿瘤学 | 1989篇 |
出版年
2024年 | 42篇 |
2023年 | 259篇 |
2022年 | 449篇 |
2021年 | 926篇 |
2020年 | 593篇 |
2019年 | 851篇 |
2018年 | 935篇 |
2017年 | 599篇 |
2016年 | 680篇 |
2015年 | 812篇 |
2014年 | 1071篇 |
2013年 | 1252篇 |
2012年 | 1879篇 |
2011年 | 1907篇 |
2010年 | 1083篇 |
2009年 | 906篇 |
2008年 | 1439篇 |
2007年 | 1397篇 |
2006年 | 1259篇 |
2005年 | 1156篇 |
2004年 | 1010篇 |
2003年 | 817篇 |
2002年 | 645篇 |
2001年 | 357篇 |
2000年 | 295篇 |
1999年 | 260篇 |
1998年 | 125篇 |
1997年 | 109篇 |
1996年 | 91篇 |
1995年 | 68篇 |
1994年 | 77篇 |
1993年 | 67篇 |
1992年 | 124篇 |
1991年 | 107篇 |
1990年 | 110篇 |
1989年 | 107篇 |
1988年 | 78篇 |
1987年 | 74篇 |
1986年 | 64篇 |
1985年 | 61篇 |
1984年 | 43篇 |
1983年 | 43篇 |
1982年 | 30篇 |
1981年 | 30篇 |
1980年 | 27篇 |
1979年 | 24篇 |
1978年 | 19篇 |
1977年 | 26篇 |
1976年 | 18篇 |
1975年 | 14篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
Amanda Bolderston Jackie Middleton Cynthia Palmaria Susan Cauti Susan Fawcett 《Journal of Medical Imaging and Radiation Sciences》2021,52(2):160-163
Lesbian, gay, bisexual, transgender, queer and two-spirit plus (LGBTQ2S+) people have distinct healthcare needs that may be unaddressed in many undergraduate healthcare curricula. The Radiation Therapy Program (RADTH) at the University of Alberta underwent a review of the three-year didactic curriculum using an online survey. The survey sought to ascertain if, where and how topics related to LGBTQ2S + healthcare are taught. Results indicated that out of 10 RADTH program faculty respondents, three teach related topics. The total time dedicated within the three-year curriculum was approximately three and a half hours. Other findings showed that faculty are interested in receiving more education in this area and would favour discussions about how to incorporate these themes into appropriate courses. This preliminary investigation demonstrated that there has been some initial work in this area, but there is more to be done. 相似文献
2.
Janitz Amanda E. Schraw Jeremy M. Xu Chao Lupo Philip J. 《Cancer causes & control : CCC》2022,33(3):483-488
Cancer Causes & Control - Congenital malformations are strong risk factors for childhood cancer. Our objective was to determine whether cancer survival differs by birth defect status among... 相似文献
3.
4.
5.
6.
Weiyu Ye Anna Olsson-Brown Robert A. Watson Vincent T. F. Cheung Robert D. Morgan Isar Nassiri Rosalin Cooper Chelsea A. Taylor Umair Akbani Oliver Brain Rubeta N. Matin Nicholas Coupe Mark R. Middleton Mark Coles Joseph J. Sacco Miranda J. Payne Benjamin P. Fairfax 《British journal of cancer》2021,124(10):1661
Background Immune checkpoint blockers (ICBs) activate CD8+ T cells, eliciting both anti-cancer activity and immune-related adverse events (irAEs). The relationship of irAEs with baseline parameters and clinical outcome is unclear.Methods Retrospective evaluation of irAEs on survival was performed across primary (N = 144) and secondary (N = 211) independent cohorts of patients with metastatic melanoma receiving single agent (pembrolizumab/nivolumab—sICB) or combination (nivolumab and ipilimumab—cICB) checkpoint blockade. RNA from pre-treatment and post-treatment CD8+ T cells was sequenced and differential gene expression according to irAE development assessed.Results 58.3% of patients developed early irAEs and this was associated with longer progression-free (PFS) and overall survival (OS) across both cohorts (log-rank test, OS: P < 0.0001). Median survival for patients without irAEs was 16.6 months (95% CI: 10.9–33.4) versus not-reached (P = 2.8 × 10−6). Pre-treatment monocyte and neutrophil counts, but not BMI, were additional predictors of clinical outcome. Differential expression of numerous gene pathway members was observed in CD8+ T cells according to irAE development, and patients not developing irAEs demonstrating upregulated CXCR1 pre- and post-treatment.Conclusions Early irAE development post-ICB is associated with favourable survival in MM. Development of irAEs is coupled to expression of numerous gene pathways, suggesting irAE development in-part reflects baseline immune activation.Subject terms: Immunotherapy, Melanoma 相似文献
7.
A mixed‐method study of effects of a therapeutic play intervention for children on parental anxiety and parents' perceptions of the intervention 下载免费PDF全文
8.
PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease 下载免费PDF全文
9.
10.