排序方式: 共有14条查询结果,搜索用时 15 毫秒
1.
A Horwich N Alsanjari R A'Hern J Nicholls D P Dearnaley C Fisher 《British journal of cancer》1992,65(5):775-778
An analysis of the primary tumour histopathology was performed on 103 patients managed by orchidectomy and surveillance for stage I seminoma. Patients have been followed for 14-141 months (median 62 months) after orchidectomy. Seventeen patients relapsed, the probability of remaining relapse free at 5 years being 82% (95% confidence intervals, 74%-88%). No patients died of progressive germ cell tumours. The only significant histological factor predicting relapse was the presence of lymphatic and vascular invasion. Four of 42 patients with neither lymphatic or vascular invasion recurred, nine of 53 patients with either lymphatic or vascular invasion recurred and three of eight cases with both lymphatic and vascular invasion recurred (P = 0.05-trend). Though initial recurrence was usually of moderate volume and confined to para-aortic nodes, eight patients were treated with chemotherapy either because of the extent of their initial relapse (four cases), or because of subsequent relapse (four cases). In view of the difficulties of identifying patients at risk and of detecting early relapse, surveillance for stage I seminoma should remain a research protocol. 相似文献
2.
3.
Aung Myat MD Florence Mouy BMBS Luke Buckner BMBS James Cockburn MD Andreas Baumbach MD Philip MacCarthy PhD Adrian P. Banning MD Nick Curzen PhD Roland Hilling-Smith MD Daniel J. Blackman MD Michael Mullen MD Mark de Belder MD Ian Cox MD Jan Kovac MD Ganesh Manoharan MD Azfar Zaman MD Douglas Muir MBChB David Smith MD Stephen Brecker MD Mark Turner PhD Saib Khogali MD Iqbal S. Malik PhD Osama Alsanjari MRCP Francesca D'Auria PhD Simon Redwood MD Bernard Prendergast DM Uday Trivedi MD Derek Robinson DPhil Peter Ludman MD Adam de Belder MD David Hildick-Smith MD 《Catheterization and cardiovascular interventions》2021,98(3):E444-E452
4.
Allahwala Usaid K. Nour Daniel Alsanjari Osama Bhatia Kunwardeep Nagaraja Vinayak Khatri Jaikirshan J. Cockburn James Hildick-Smith David Sakata Yasuhiko Ward Michael Weaver James C. Bhindi Ravinay 《Journal of thrombosis and thrombolysis》2021,51(4):1005-1016
Journal of Thrombosis and Thrombolysis - Acute coronary collateralisation of an infarct-related arterial (IRA) territory may be identified during angiography for ST elevation myocardial infarction... 相似文献
5.
High resolution magnetic resonance imaging in adults with partial or secondary generalised epilepsy attending a tertiary referral unit.
下载免费PDF全文
![点击此处可从《Journal of neurology, neurosurgery, and psychiatry》网站下载免费的PDF全文](/ch/ext_images/free.gif)
L M Li D R Fish S M Sisodiya S D Shorvon N Alsanjari J M Stevens 《Journal of neurology, neurosurgery, and psychiatry》1995,59(4):384-387
In the past the underlying structural abnormalities leading to the development of chronic seizure disorders have usually only been disclosed by histological examination of surgical or postmortem material, due to their often subtle nature that was beyond the resolution of CT or early MRI. The MRI findings in 341 patients with chronic, refractory epilepsy attending The National Hospital for Neurology and Neurosurgery and Chalfont Centre for Epilepsy are reported. Studies were performed on a 1.5 Tesla scanner with a specific volumetric protocol, allowing the reconstruction of 1.5 mm contiguous slices throughout the whole brain. Direct visual inspection of the two dimensional images without the use of additional quantitative measures showed that 254/341 (74%) were abnormal. Twenty four (7%) patients had more than one lesion. The principal MRI diagnoses were hippocampal asymmetry (32%), cortical dysgenesis (12%), tumour (12%), and vascular malformation (8%). Pathological confirmation was available from surgical specimens in 70 patients and showed a very high degree of sensitivity and specificity for the different entities. The advent of more widely available high resolution MRI should make it possible to identify the underlying pathological substrate in most patients with chronic partial epilepsy. This will allow a fundamental reclassification of the epilepsies for both medical and surgical management, with increasing precision as new methods (both of acquisition and postprocessing) are added to the neuroimaging battery used in clinical practice. 相似文献
6.
In-hospital stroke after transcatheter aortic valve implantation: A UK observational cohort analysis
Aung Myat MD Luke Buckner BMBS Florence Mouy BMBS James Cockburn MD Andreas Baumbach MD Adrian P. Banning MD Daniel J. Blackman MD Nick Curzen PhD Philip MacCarthy PhD Michael Mullen MD Mark de Belder MD Ian Cox MD Jan Kovac MUDr Stephen Brecker MD Mark Turner PhD Saib Khogali MD Iqbal S. Malik PhD Osama Alsanjari MRCP Simon Redwood MD Bernard Prendergast DM Uday Trivedi MD Derek Robinson DPhil Peter Ludman MD Adam de Belder MD David Hildick-Smith MD 《Catheterization and cardiovascular interventions》2021,97(4):E552-E559
7.
AIMS: To report and confirm the identity of tumour cells showing leiomyosarcomatous differentiation in a regional lymph node containing metastatic Merkel cell tumour. METHODS AND RESULTS: A 79-year-old woman was found to have metastatic Merkel cell tumour within an axillary lymph node 4 months after excision of the primary tumour from the forearm. The lymph node was effaced by tumour identical to that of the primary tumour but there was an additional focus of loose spindle cells. Immunocytochemical staining showed the coexpression of cytokeratin 20, neurofilament and desmin in these sarcomatous cells. CONCLUSION: This, to the best of our knowledge, is the first report of Merkel cell carcinoma showing sarcomatous differentiation, and adds to the expanding morphological spectrum of malignant biphasic tumours. 相似文献
8.
I. Nelson M. G. Hanna N. Alsanjari F. Scaravilli J. A. Morgan-Hughes A. E. Harding 《Annals of neurology》1995,37(3):400-403
A novel mitochondrial DNA transfer RNA mutation at position 5549 was identified in a patient with dementia, chorea, cerebellar ataxia, deafness, and peripheral neuropathy in the absence of clinical myopathy. Muscle biopsy specimens showed ragged red and cytochrome oxidase-negative fibers, and reduced complex I activity on polarography. There was diffuse neuronal loss and gliosis throughout the brain on postmortem examination. The heteroplasmic mutation had a widespread distribution in autopsy tissues. 相似文献
9.
Alsanjari ON de Lusignan S van Vlymen J Gallagher H Millett C Harris K Majeed A 《International journal of clinical practice》2012,66(1):37-43
Background: End‐digit preference (EDP) is a known cause of inaccurate BP recording. Distortion has been reported around pay‐for‐performance (P4P) indicators. Methods: We studied sequential datasets (n = 148,000 to n = 900,000) and performed a longitudinal analysis of CONDUIT data (n = 250,000) over a 10‐year period. We examined general trends in EDP and investigated the impact of diabetes and chronic kidney disease (CKD) P4P targets. Results: EDP reduces over time in both datasets; the percentage of patients with a zero EDP declined from 70% to 27% and 68% to 26% for SBP and DBP respectively. There is more zero EDP at the extremes of BP, but in people with chronic disease, the use of zero EDP was mainly seen at higher BP levels. P4P targets are associated with increased preference for the even end‐digit just below target: in diabetes odds ratio (OR) is 1.47 (p = 0.003) for SBP, 1.19 (p = 0.09) for DBP and in CKD OR 1.65 (p < 0.001) for SBP and 1.48 (p = 0.0001) for DBP. Trends observed in pilot data were validated with a longitudinal set. Conclusions: The decline in EDP is levelling off and P4P targets are associated with sub‐target‐EDP. Primary care should automate BP measurement and recording. 相似文献
10.