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1.
Brian Walls Oisín Murtagh Sergey I. Bozhko Andrei Ionov Andrey A. Mazilkin Daragh Mullarkey Ainur Zhussupbekova Dmitry A. Shulyatev Kuanysh Zhussupbekov Nikolai Andreev Nataliya Tabachkova Igor V. Shvets 《Materials》2022,15(21)
The strongly correlated electron material, vanadium dioxide (VO), has seen considerable attention and research application in metal-oxide electronics due to its metal-to-insulator transition close to room temperature. Vacuum annealing a VO(010) single crystal results in Wadsley phases (VO, n > 1) and VO. The resistance changes by a factor of 20 at 342 K, corresponding to the metal-to-insulator phase transition of VO. Macroscopic voltage-current measurements with a probe separation on the millimetre scale result in Joule heating-induced resistive switching at extremely low voltages of under a volt. This can reduce the hysteresis and facilitate low temperature operation of VO devices, of potential benefit for switching speed and device stability. This is correlated to the low resistance of the system at temperatures below the transition. High-resolution transmission electron microscopy measurements reveal a complex structural relationship between VO, VO and VO crystallites. Percolation paths incorporating both VO and metallic VO are revealed, which can reduce the resistance below the transition and result in exceptionally low voltage resistive switching. 相似文献
2.
Mukharram M. Bikbov Timur R. Gilmanshin Rinat M. Zainullin Ellina M. Rakhimova Iuliia A. Rusakova Albina A. Fakhretdinova Azaliia M. Tuliakova Gyulli M. Kazakbaeva Songhomitra Panda-Jonas Kamilia R. Safiullina Nataliia I. Bolshakova Ainur V. Gizzatov Ildar P. Ponomarev Nikolai A. Nikitin Nail E. Baimukhametov Jost B. Jonas 《Eye (London, England)》2022,36(12):2294
BackgroundTo assess potential associations between the ankle-brachial blood pressure index (ABI) and ocular disorders.MethodsIn the population-based cross-sectional Russian Ural Eye and Medical Study including 5,899 (80.5%) out of 7328 eligible participants aged 40+ years, the participants underwent a series of ocular and medical examinations including measurement of ABI.ResultsBlood pressure measurements of both arms and ankles were available for 3187 (54.0%) individuals. The mean ABI was 1.26 ± 0.19 (median:1.20; range: 0.61, 2.20). In multivariate analysis, a higher ABI was associated with younger age (P < 0.001; non-standardized regression coefficient B: −0.001; 95% confidence interval (CI): −0.002, −0.001), female sex (P < 0.001; B: 0.03; 95% CI: 0.02, 0.04), lower body mass index (P < 0.001; B: −0.004; 95% CI: −0.006, −0.003), lower waist-to-hip ratio (P = 0.01; B: −0.10; 95% CI: −0.17, −0.02), lower glucose serum concentration (P = 0.008; B: −0.005; 95% CI: −0.009, −0.001), lower prevalence of arterial hypertension (P < 0.001; B: −0.14; 95% CI: −0.16, −0.12), higher mean systolic blood pressure (P < 0.001; B: 0.003; 95% CI: 0.002, 0.003), and higher prevalence of any alcohol consumption (P < 0.001; B: 0.03; 95% CI: 0.02, 0.04). In that multivariate model, prevalence of glaucoma (P = 0.67) as a whole, open-angle glaucoma (P = 0.86) and angle-closure glaucoma (P = 0.54), stage of glaucomatous optic neuropathy (P = 0.57), prevalence of age-related macular degeneration (P = 0.88), prevalence and stage of diabetic retinopathy (P = 0.30, and P = 0.29, respectively), nuclear cataract (P = 0.32, and P = 0.41, resp.), cortical cataract (P = 0.33, and P = 0.92, resp.), subcapsular cataract (P = 0.74 and P = 0.60, resp.), and pseudoexfoliation (P = 0.44 and P = 0.47, resp.), intraocular pressure (P = 0.52), axial length (P = 0.20), and peripapillary retinal nerve fibre layer thickness (P = 0.55) were not significantly associated with the ABI.ConclusionsIn this ethnically mixed population from Russia, none of the major ocular diseases was associated with ABI suggesting that subclinical atherosclerosis is not markedly associated with the aetiology of these ocular disorders.Subject terms: Retinal diseases, Lens diseases 相似文献
3.
Punjabi NH Richie EL Simanjuntak CH Harjanto SJ Wangsasaputra F Arjoso S Rofiq A Prijanto M Julitasari Yela U Herzog C Cryz SJ 《Vaccine》2006,24(11):1776-1785
Widespread use of Haemophilus influenzae type b (Hib) conjugated vaccine in industrialized countries has resulted in a dramatic decline in the incidence of invasive Hib diseases, but the vaccine's cost has prevented its inclusion in basic immunization programs in developing countries. To overcome this problem, combination with diphtheria-tetanus-pertussis (DTP) vaccine or reduction in the dose of Hib vaccine has been proposed. To evaluate the immunogenicity and adverse reactions from lower doses of Hib-polyribosylphosphate (PRP) conjugated with tetanus toxoid (PRP-T), a double-blind study was conducted in Jakarta, Indonesia, and its suburbs. A total of 1048 infants 6 weeks to 6 months of age received three doses of DTP vaccine combined with the usual 10 microg dose or with a reduced dose of 5, 2.5 or 1.25 microg of PRP-T at two-monthly intervals. Antibodies were measured prior to the first dose and 4-6 weeks following the third dose. Adverse reactions were similar among all four groups. The only significant difference was a higher rate of irritability (p<0.02) and of temperature elevation >38 degrees C (p<0.009) after doses 1 and 2 in the lowest dose group (1.25 microg PRP-T) compared to the other groups. All participants tested had a 4-fold increase in antibodies against all DTP antigens. In addition, after a fourth booster dose of Hib, 99.6% of infants produced >or=0.15 microg/ml of antibody to Hib-PRP, and 96.4% showed levels >or=1.0 microg/ml after primary immunization, level that correlate with short- and long-term immunity, respectively. Antibody titers to the PRP antigen showed no significant differences among dosage groups with the exception of the 5.0 microg group, which had a significantly higher GMC than the 1.25 microg group (p<0.012). This study demonstrates that primary vaccination with half, one-fourth, or one-eighth of the usual dose of PRP-T, combined with DTP vaccine, produces protective immune responses, and has side effects that are comparable to DTP vaccination alone. In these lower dosages, PRP-T conjugate vaccine can lower vaccine costs to a level that is affordable for infant immunization programs in developing countries. 相似文献
4.
Li-Cheng Jheng Afira Ainur Rosidah Steve Lien-Chung Hsu Ko-Shan Ho Chun-Jern Pan Cheng-Wei Cheng 《RSC advances》2021,11(17):9964
Carbon nanofibers functionalized with aminobenzoyl groups (CNF–aminobenzoyl) were prepared via direct Friedel–Crafts acylation in polyphosphoric acid. The functionalization of CNFs was characterized using XPS, FTIR, TGA, and Raman analyses. Hexafluoroisopropylidene-containing polybenzimidazole (6FPBI) composite membranes containing pristine CNFs or CNF–aminobenzoyl were prepared using solvent-assisted dispersion and solvent-casting methods. In this work, the influence of the incorporation of functionalized CNFs on several physicochemical properties of the 6FPBI nanocomposite membranes, including their thermal stability, mechanical strength, and acid doping level, was studied. The results showed that CNF–aminobenzoyl provided better mechanical reinforcement for the nanocomposite membrane, compared to pristine CNF. The SEM observation confirmed the good compatibility between the CNF–aminobenzoyl fillers and the 6FPBI matrix. For the 0.3 wt% CNF–aminobenzoyl/6FPBI composite membrane, the tensile stress was increased by 12% to be 78.9 MPa (as compared to the 6FPBI membrane), the acid doping level was improved to 12.0, and the proton conductivity at 160 °C was measured above 0.2 S cm−1. Furthermore, the fuel cell performance of the membrane electrolyte assembly (MEA) for each nanocomposite membrane was evaluated. The maximum power density at 160 °C was found up to 461 mW cm−2 for the MEA based on the 0.3 wt% CNF–aminobenzoyl/6FPBI composite membrane.Carbon nanofibers functionalized with aminobenzoyl groups (CNF–aminobenzoyl) were prepared via direct Friedel–Crafts acylation in polyphosphoric acid. 相似文献
5.
Akilzhanova A Takamura N Kusano Y Karazhanova L Yamashita S Saito H Aoyagi K 《Asia Pacific journal of clinical nutrition》2008,17(2):325-329
We recently suggested that due to insufficient intake of vegetables, low folate status and mild homocysteinemia might exist in the Kazakh population. To clarify the determinants of homocysteine concentrations among this population, we determined concentrations of serum folate, albumin, creatinine, vitamin B12, and the C677T/ MTHFR genotype in 110 Kazakh individuals and compared these with plasma total homocysteine. In Kazakh, after adjustment for age and sex, folate was correlated with plasma total homocysteine, whereas concentrations in those with the TT genotype was almost twice as high as in those with the CC and CT genotypes (19.7+/-1.8 micromol/L vs. 10.7+/-0.5 micromol/L, p<0.001). Our results suggest that the C677T/MTHFR genotype is associated with homocysteine concentrations in this population and this association might be affected by other factors, such as folate status. 相似文献
6.
Armen Yuri Gasparyan Ainur B. Kumar Marlen Yessirkepov Olena Zimba Bekaidar Nurmashev George D. Kitas 《Journal of Korean medical science》2022,37(22)
Global health is evolving as a discipline aiming at exploring needs and offering equitable health services for all people. Over the past four decades, several global initiatives have been introduced to improve the accessibility of primary health care (PHC) and solve most health issues at this level. Historically, the 1978 Alma-Ata and 2018 Astana Declarations were perhaps the most important documents for a comprehensive approach to PHC services across the world. With the introduction of the United Nations Sustainable Development Goals in 2015, developments in all spheres of human life and multi-sectoral cooperation became the essential action targets that could contribute to improved health, well-being, and safety of all people. Other global initiatives such as the Riyadh Declaration on Digital Health and São Paulo Declaration on Planetary Health called to urgent action to employ advanced digital technologies, improve health data processing, and invest more in research management. All these initiatives are put to the test in the face of the coronavirus disease 2019 (COVID-19) pandemic and other unprecedented threats to humanity. 相似文献
7.
Zhabagin Maxat Sarkytbayeva Aliya Tazhigulova Inkar Yerezhepov Dauren Li Svetlana Akilzhanov Rakhmetolla Yeralinov Alibek Sabitov Zhaxylyk Akilzhanova Ainur 《International journal of legal medicine》2019,133(4):1029-1032
To improve available databases of forensic interest, all Y-STR haplotypes from Kazakh population were presented in this study. The reference database accumulated almost 3650 samples from academic and citizen science. Additionally, 27 Y-STR from Yfiler Plus System were first analyzed in 300 males from Kazakh (Qazaq) populations residing in Kazakhstan. The data is available in the YHDR under accession numbers YA004316 and YA004322. A total of 270 unique haplotypes were observed. Discrimination capacity was 90%. Obtained Y-STR haplotypes exhibited a high intra-population diversity. Analysis of pairwise genetic distances showed lowest RST values from Uighur and Mongolian populations.
相似文献8.
Karabayeva Raushan Valeriy Benberin Tamara Vochshenkova Dmitriy Babenko Ainur Sibagatova 《Medicine》2021,100(6)
Cardiovascular diseases are one of the key health issues in Kazakhstan. According to the WHO, the prevalence of arterial hypertension (AH) was 28% in males and 25% in females in 2015, which puts up vastly to premature mortality from non-communicable diseases.The search for genetic features of target organ lesions processes in AH is relevant. The goal of this study was to search for the genetic markers of myocardial remodeling (MR) and carotid artery remodeling (CAR).A total of 866 hypertensive individuals were recruited in Nur-Sultan, Kazakhstan. Their blood was genotyped for 9 single nucleotide polymorphisms (SNPs) of the eighth chromosome to find an association with remodeling. The analysis was carried out in the group pairs (control and CAR, control and MR, and control and CAR and MR). The genotype–phenotype association was assessed using 5 different inheritance models: dominant, codominant, recessive, overdominant, and log-additive.Statistically significant results were found for 3 SNPs (rs2407103, rs11775334, rs2071518) which minor alleles enlarged risks of MR and CAR in AH in the studied population. Three polymorphisms have previously been associated with АН and some other traits like pulse pressure and blood glucose in other ethnic populations: rs2407103 – in Afro-American population, rs11775334 – in the European population, rs2071518 is well studied in various ethnic populations (European, South Asian, Afro-American, Hispanic, East Asian). 相似文献
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Simanjuntak CH Punjabi NH Wangsasaputra F Nurdin D Pulungsih SP Rofiq A Santoso H Pujarwoto H Sjahrurachman A Sudarmono P von Seidlein L Acosta C Robertson SE Ali M Lee H Park J Deen JL Agtini MD Clemens JD 《Journal of health, population, and nutrition》2004,22(2):119-129
Visits to household during a census in an impoverished area of north Jakarta were used for exploring the four-week prevalence of diarrhoea, factors associated with episodes of diarrhoea, and the patterns of healthcare use. For 160,261 urban slum-dwellers, information was collected on the socioeconomic status of the household and on diarrhoea episodes of individual household residents in the preceding four weeks. In households with a reported case of diarrhoea, the household head was asked which form of healthcare was used first. In total, 8,074 individuals (5%)--13% of children aged less than five years and 4% of adults--had a diarrhoea episode in the preceding four weeks. The two strongest factors associated with a history of diarrhoea were a diarrhoea episode in another household member in the four weeks preceding the interview (adjusted odds ratio [OR] 11.1; 95% confidence interval [CI] 10.4-11.8) and age less than five years (adjusted OR 3.4; 95% CI 3.2-3.5). Of the 8,074 diarrhoea cases, 1,969 (25%) treated themselves, 1,822 (23%) visited a public-health centre (PHC), 1,462 (18%) visited a private practitioner or a private clinic, 1,318 (16%) presented at a hospital, 753 (9%) bought drugs from a drug vendor, and 750 (9%) used other healthcare providers, such as belian (traditional healers). Children with diarrhoea were most often brought to a PHC, a private clinic, or a hospital for treatment. Compared to children, adults with diarrhoea were more likely to treat themselves. Individuals from households in the lowest-income group were significantly more likely to attend a PHC for treatment of diarrhoea compared to individuals from households in the middle- and higher-income groups. 相似文献