全文获取类型
收费全文 | 28965篇 |
免费 | 1933篇 |
国内免费 | 99篇 |
专业分类
耳鼻咽喉 | 336篇 |
儿科学 | 750篇 |
妇产科学 | 621篇 |
基础医学 | 3447篇 |
口腔科学 | 500篇 |
临床医学 | 2792篇 |
内科学 | 5823篇 |
皮肤病学 | 381篇 |
神经病学 | 2030篇 |
特种医学 | 764篇 |
外国民族医学 | 2篇 |
外科学 | 4618篇 |
综合类 | 781篇 |
一般理论 | 36篇 |
预防医学 | 2785篇 |
眼科学 | 744篇 |
药学 | 2558篇 |
中国医学 | 237篇 |
肿瘤学 | 1792篇 |
出版年
2023年 | 271篇 |
2022年 | 676篇 |
2021年 | 1005篇 |
2020年 | 621篇 |
2019年 | 831篇 |
2018年 | 932篇 |
2017年 | 667篇 |
2016年 | 607篇 |
2015年 | 765篇 |
2014年 | 1069篇 |
2013年 | 1337篇 |
2012年 | 1939篇 |
2011年 | 1888篇 |
2010年 | 1068篇 |
2009年 | 902篇 |
2008年 | 1532篇 |
2007年 | 1513篇 |
2006年 | 1372篇 |
2005年 | 1321篇 |
2004年 | 1152篇 |
2003年 | 1047篇 |
2002年 | 915篇 |
2001年 | 752篇 |
2000年 | 700篇 |
1999年 | 590篇 |
1998年 | 235篇 |
1997年 | 184篇 |
1996年 | 172篇 |
1995年 | 184篇 |
1994年 | 120篇 |
1993年 | 122篇 |
1992年 | 338篇 |
1991年 | 309篇 |
1990年 | 312篇 |
1989年 | 276篇 |
1988年 | 246篇 |
1987年 | 267篇 |
1986年 | 221篇 |
1985年 | 241篇 |
1984年 | 197篇 |
1983年 | 153篇 |
1982年 | 122篇 |
1981年 | 104篇 |
1979年 | 177篇 |
1978年 | 131篇 |
1977年 | 107篇 |
1975年 | 114篇 |
1974年 | 97篇 |
1973年 | 118篇 |
1972年 | 105篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
P. A. Hannan J. A. Khan A. Khan S. Safiullah 《Indian journal of pharmaceutical sciences》2016,78(1):2-7
Dosage form is a mean used for the delivery of drug to a living body. In order to get the desired effect the drug should be delivered to its site of action at such rate and concentration to achieve the maximum therapeutic effect and minimum adverse effect. Since oral route is still widely accepted route but having a common drawback of difficulty in swallowing of tablets and capsules. Therefore a lot of research has been done on novel drug delivery systems. This review is about oral dispersible tablets a novel approach in drug delivery systems that are now a day''s more focused in formulation world, and laid a new path that, helped the patients to build their compliance level with the therapy, also reduced the cost and ease the administration especially in case of pediatrics and geriatrics. Quick absorption, rapid onset of action and reduction in drug loss properties are the basic advantages of this dosage form. 相似文献
2.
3.
C. Jacquet F. Goehringer E. Baux J.A. Conrad M.O. Ganne Devonec J.L. Schmutz G. Mathey H. Tronel T. Moulinet I. Chary-Valckenaere T. May C. Rabaud 《Médecine et maladies infectieuses》2019,49(2):112-120
Objective
The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.Patients and methods
We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.Results
A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.Conclusions
This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses. 相似文献4.
5.
Prevalence of Potentially Inappropriate Prescribing Among Hong Kong Older Adults: A Comparison of the Beers 2003, Beers 2012, and Screening Tool of Older Person's Prescriptions and Screening Tool to Alert doctors to Right Treatment Criteria 下载免费PDF全文
6.
7.
Effects of poor glucose handling on arterial stiffness and left ventricular mass in normal children.
AIM: Cardiovascular risk factors can be present in children and young adults. We previously found abnormal microvascular function in children who had glucose intolerance and insulin resistance. The aim of the present study was to investigate whether they also have abnormalities in left ventricular mass (LVM) and arterial stiffness. METHODS: We measured heart dimensions and LVM using echocardiography, and arterial stiffness using pulse wave analysis in 23 children with good glucose handling (postfeeding glucose: 3.9 to 5 mmol/L) and 21 with poor glucose handling (7.7 to 11.4 mmol/L). RESULTS: The time to pulse reflection was slightly shorter in the poorer glucose handlers (mean+/-SD: 143+/-10 vs 153+/-20 ms, P=0.04), suggestive of increased arterial stiffness. Also in this group, there were significant relationships between intraventricular septal thickness, blood pressure and body mass index, but not in the normal glucose handlers. CONCLUSIONS: We have found that normal children who are in the lowest quintile of glucose tolerance in comparison with their peers are exhibiting the first signs of arterial stiffening. In addition, we have seen the beginnings of a relationship between blood pressure, body mass index and left ventricular enlargement in this group. While these changes may not yet be clinically significant, their emergence might be further evidence of early predisposition to cardiovascular disease. 相似文献
8.
9.
10.
The effect of bracing on proprioception of knees with anterior cruciate ligament injury. 总被引:2,自引:0,他引:2
Bruce D Beynnon Lars Good May Arna Risberg 《The Journal of orthopaedic and sports physical therapy》2002,32(1):11-15
This paper is a comprehensive review on the effect of bandaging, bracing, and neoprene sleeves on knee proprioception following anterior cruciate ligament (ACL) injury and reconstruction with a focus on studies that have measured joint position sense and threshold to detection of passive knee motion. Disruption of the ACL does not appear to alter joint position sense soon after injury, although there is evidence that in some subjects deterioration may occur over time. An ACL tear creates a deficit in the threshold to detection of passive knee motion soon after injury and in those with chronic tears. The magnitude of worsening is less then 1.0 degree of movement in flexion-extension and of questionable concern from a clinical and functional perspective. Application of a functional brace or neoprene sleeve to the ACL-deficient limb does not improve the threshold to detection of passive knee motion; however, application of an elastic bandage to a knee with an ACL tear improves joint position sense. Reconstruction of a torn ACL is associated with a deficit in the threshold to detection of passive knee motion, and during the first year of healing the use of a neoprene sleeve provides improvement. Two years following ACL reconstruction there is no deficit in the threshold to detection of passive knee motion and the use of a brace has no effect on this outcome. 相似文献