主动脉瓣硬化和颈动脉斑块对冠心病的诊断价值

动脉粥样硬化广泛累及全身性动脉系统,主要累及大、中型动脉,特别是中型动脉,如冠状动脉和颈动脉,表现为斑块沉积和管腔狭窄,以不规则性瓣膜增厚为主要表现的主动脉瓣硬化（AVS）与动脉粥样硬化有关，被认为是动脉粥样硬化在血管壁以外的另一种表现形式，     

老年子宫内膜癌患者临床病理分析及孕激素治疗对预后的作用

Objective To retrospectively analyze clinicopathological features and prognosis effect of progesterone therapy in elderly patients with endometrial carcinoma. Methods Two hundred and thirty-five patients were divided into three groups according to age: 30-49 years old group (n=54), 50-59 years old group (n= 102) and 60-82 years old group (n= 79). The relationship between age and clinicopathological features was analyzed, and the prognosis effect of progesterone therapy in patients of 60-82 years old was assesed. Results The incidences of special pathological type of endometrial cancer (serous eystadenocarcinoma, clear cell carcinoma and squamous cell carcinoma) , operation-pathological stage ≥Ⅲ and low differentiation were increased with advancing age. The incidences of the above mentioned special pathological type of endometrial cancer were 20.4% (11/54), 38. 2%(39/63), 48.1%(38/79) in the three groups, respectively, and there were statistical significances among the three groups (χ<'2> = 10.039, P<0.01). The positive rate of progesterone receptor was significantly decreased in the three groups (57.4% (31/54)vs. 45.1% (46/ 102) vs. 25.3%(20/79), P<0. 01]. The remission rate of progesterone therapy was higher (18/23) than that of radiotherapy and (or) chemotherapy (4/8) (78.3% vs. 50%, Z= 1.46, P<0. 05). Conclusions The incidence of clinical pathological factors of endometrial cancer is increased with advancing age, and the prognosis of progesterone therapy is better than treatment with radiotherapy and (or) chemotherapy.     

老年子宫内膜癌患者临床病理分析及孕激素治疗对预后的作用

目的 回顾性分析老年子宫内膜癌患者临床病理特征与孕激素治疗的预后. 方法 235例子宫内膜癌患者按年龄分3组:30～49岁组54例、50～59岁组102例和60～82岁组79例,分析年龄与影响患者预后的临床病理因素间的关系,并随访60～82岁组患者行孕激素治疗的预后.结果 随增龄,特殊病理类型(浆液性乳头状囊腺癌、透明细胞癌、鳞癌)、手术病理分期三期及以上和低分化子宫内膜癌发生率升高,其中特殊病理类型30～49岁组、50～59岁组和60～82岁组分别为20.4%(11/54)、38.2%(39/63)、48.1%(38/79),3组间比较差异有统计学意义(χ2=10.039,P<0.01),而孕激素受体阳性表达率明显降低[分别为57.4%(31/54)、45.1%(46/102)、25.3%(20/79),P<0.01];术后行孕激素治疗(23例)缓解率78.3%(18例),高于放疗和(或)化疗(8例)的缓解率50.0%(4例),差异有统计学意义(Z=1.46,P<0.05). 结论 子宫内膜癌患者随年龄增大,与预后差相关的临床病理因素发生率增高,60～82岁组孕激素治疗预后好于放疗和(或)化疗.     

1%聚桂醇注射液泡沫硬化剂治疗下肢大隐静脉曲张的疗效观察

目的探讨泡沫硬化剂治疗下肢静脉曲张的效果。方法选择86例下肢静脉曲张患者在彩超检测下应用1%聚桂醇泡沫硬化剂注射104条曲张病肢。结果 104条病肢均成功注射,平均每条肢体泡沫硬化剂用量6⁸ml;仅13条病肢1月后行第2次治疗。随访6个月全部患者症状消失或明显改善,曲张靶静脉治疗区硬结形成、吸收并纤维条索形成。结论聚桂醇泡沫泡沫硬化剂治疗大隐静脉曲张疗效显著,无严重并发症。     

重楼皂甙在乳汁中的测定结果分析

重楼皂甙是宫血宁胶囊的主要成分 ,主要用于妇产科止血、消炎 ,辅助子宫复旧的治疗。 2 0 0 3年 2～ 4月北京医院妇产科与首都师范大学生物医学研究中心合作对 12例产妇乳汁中重楼皂甙的含量进行了测定分析。1　资料与方法1 1　药品与试剂　重楼皂甙对照品 ,质量分数 (浓度 )为99 8% ,由云南白药集团提供。宫血宁胶囊 ,由云南白药集团提供。甲醇 ,色谱醇 ,Fisher公司产品。超纯水 ,自制。受试者乳汁样品由北京医院妇产科提供。1 2　仪器　英国MICROMASS Q Tof液相色谱 -质谱联用仪 ;kromasilC18色谱柱 2 5 0mm× 4 6mm ;德国CHRIST…     

腹膜播散性卵巢恶性甲状腺肿临床分析

目的 探讨并文献复习卵巢恶性甲状腺肿的病因、临床特点、诊断及治疗。方法 报告1例37岁未育妇女患卵巢恶性甲状腺肿。结果 卵巢甲状腺肿起源于卵巢原始生殖细胞，是一种单胚层高度特异性成熟性畸胎瘤，卵巢恶性甲状腺肿很少见，临床上该病无特异性症状和体征，肿瘤必须是卵巢甲状腺肿恶变者，有明确的侵犯和（或）转移。无生育要求者，施行卵巢癌细胞减灭术及甲状腺切除术，术后予以^131 Ⅰ放疗。结论 MSO是罕见疾病，只能依靠病理才能确诊，治疗包括手术和^131 Ⅰ放疗。     

老年子宫内膜癌患者临床病理分析及孕激素治疗对预后的作用

Objective To retrospectively analyze clinicopathological features and prognosis effect of progesterone therapy in elderly patients with endometrial carcinoma. Methods Two hundred and thirty-five patients were divided into three groups according to age: 30-49 years old group (n=54), 50-59 years old group (n= 102) and 60-82 years old group (n= 79). The relationship between age and clinicopathological features was analyzed, and the prognosis effect of progesterone therapy in patients of 60-82 years old was assesed. Results The incidences of special pathological type of endometrial cancer (serous eystadenocarcinoma, clear cell carcinoma and squamous cell carcinoma) , operation-pathological stage ≥Ⅲ and low differentiation were increased with advancing age. The incidences of the above mentioned special pathological type of endometrial cancer were 20.4% (11/54), 38. 2%(39/63), 48.1%(38/79) in the three groups, respectively, and there were statistical significances among the three groups (χ<'2> = 10.039, P<0.01). The positive rate of progesterone receptor was significantly decreased in the three groups (57.4% (31/54)vs. 45.1% (46/ 102) vs. 25.3%(20/79), P<0. 01]. The remission rate of progesterone therapy was higher (18/23) than that of radiotherapy and (or) chemotherapy (4/8) (78.3% vs. 50%, Z= 1.46, P<0. 05). Conclusions The incidence of clinical pathological factors of endometrial cancer is increased with advancing age, and the prognosis of progesterone therapy is better than treatment with radiotherapy and (or) chemotherapy.     

氯硝柳胺杀虫丁和四聚乙醛杀螺效果比较研究

目的：筛选一种合适的杀螺锴物。方法：采用室内浸杀,喷洒,喷粉,上爬,毒性试验及现场浸杀,喷洒,喷粉,沿边浸杀试验,对氯硝柳胺与杀虫丁,四聚乙醛等进行平行比较试验,结果：在室内23－25℃气温条件下,氯硝柳胺杀螺作用优于杀虫丁和四聚乙醛,抑制钉螺上爬作用不及杀虫丁,鱼毒大于杀虫丁,在现场28－35℃气温条件下,氯硝柳胺和杀虫丁杀螺作用相仿。沿边浸杀氯硝柳胺优于四聚乙醛,喷粉杀螺氯硝柳胺与四聚乙醛相仿,结论：在现阶段氯硝柳胺仍是一种较好的杀螺药物。     

阴道骶棘韧带悬吊术治疗子宫和阴道穹隆脱垂

目的探讨经阴道骶棘韧带悬吊术治疗子宫脱垂和阴道穹隆脱垂的临床意义。方法2003年5月至2006年12月，对46例中、重度子宫脱垂和阴道穹隆脱垂患者行经阴道骶棘韧带悬吊术，术后1、3、6、12个月定期随访。主观治愈定义为术后患者无任何自觉症状，客观治愈定义为术后阴道顶端位于坐骨棘水平。结果平均手术时间45min（30～90min），术中平均失血量105ml（60-200ml），手术无膀胱、直肠损伤。术后平均住院时间4．7d（4～8d），导尿管引流平均2．3d（2～7d）。术后随访1～42个月，平均10个月，主观治愈率和客观治愈率均为98％。结论对子宫脱垂和阴道穹隆脱垂患者，采用阴道骶棘韧带悬吊术是一种安全、有效的治疗方法。     

不同厂家氯硝柳胺与烟酰苯胺复配灭螺实验研究

目的掌握不同厂家氯硝柳胺与烟酰苯胺复配的灭螺效果。方法将氯硝柳胺与烟酰苯胺按1∶1的比例进行复配形成复合物(简称氯烟复合物),在室内进行浸杀和喷洒灭螺实验并观察钉螺触药上爬及鱼类急性毒性情况。结果在室温23～25℃条件下,采用0.2mg/L氯烟复合物,室内浸泡48h,3个厂家氯烟复合物淮南组、吴江组和四川组的钉螺死亡率分别为93.3%、94.7%和95.4%。采用0.4g/m氯烟复合物,室内喷洒248h,3个厂家氯烟复合物淮南组、吴江组和四川组的钉螺死亡率分别为97%、96%和96%。钉螺接触氯烟复合物的上爬率比烟酰苯胺下降71.9%,2组钉螺上爬率差异有统计学意义(P<0.01)。对鱼的急性毒性,氯烟复合物比氯硝柳胺下降50%左右。结论不同厂家氯硝柳胺和烟酰苯胺通过复配后均可获得增效灭螺的作用。