跖跗关节骨折脱位诊治体会

随着交通、工伤事故增多，跖跗关节（Lisfrane关节）损伤明显增多。由于跖跗关节为中足一复杂的复合性结构，处于足弓顶部，在步态中支撑体重，它的损伤、破坏常严重影响步行或致足畸形，此类损伤在临床中并不少见，易漏诊，因其结构复杂，在诊治中易出现失误。我院2001年6月～2005年6月共收治跖跗关节骨折脱位12例，现分析总结如下。     

膀胱肉瘤样癌1例

患者 ,男 ,75岁。血尿 2个月 ,加重伴尿频、尿急、尿痛 1个月于 2 0 0 2年 2月 7日入院。患者 2个月前无明显诱因出现全程肉眼血尿 ,近 1个月加重 ,多次尿中见不规则血凝块 ,伴尿频、尿急、尿痛。在当地Ｂ超检查怀疑膀胱结石 ,经治疗无效。患病后无发热、腰痛、消瘦。体检 :双肾、输尿管区无压痛 ,未扪及包块 ,膀胱区无膨隆及包块 ,耻骨上区压痛。Ｂ超检查 :右肾盂、肾盏中度扩张 ,右输尿管全程扩张 ,直径 0 .9ｃｍ ,膀胱右后壁探及 7.4ｃｍ× 6 .3ｃｍ回声不均团块 ,边界不清 ,形态不规则 ,膀胱内探及 2 .3ｃｍ× 1 .5ｃｍ强光团 ,边界清 ,…     

PET/CT在评价及观察大鼠肺癌放疗效果中的应用

Objective The aim of this study was to understand the role of PET/CT in monitoring the therapeutic effect of radiotherapy (RT) on lung cancer with Wistar rats. Methods Thirty Wistar in-bred strain rats (6-8 weeks, weighed 180-280 g, female, ordinary) were made into Lewis pulmonary tumor model rats. 18F-fluorodeoxyglucose (FDG) PET/CT was performed when tumor reached 1.5-2.0 cm in greatest diameter (4-6 weeks) as a baseline. In order to get the optimal time point of PET/CT for moni-toring RT effect in rat cancer model, PET/CT was performed at the 3rd day, 1st, 2nd, 3rd, and 4th week after giving single dose of 5 Gy to each rat. Standardized uptake values (SUV) from FDG PET were measured and rats were sacrificed at different time point for validation. Besides, the expressions of glucose transport1 (Glut1) in tumor tissue were studied using immunohistochemistry. The level of tumor cell apoptosis, degra-dation, and necrosis were observed. SPSS 11.0 software was used for data analyses. Results A negative correlation of SUV uptake and time after RT and negative correlation of Glut1 expression and time after RT were observed in rat tumors, respectively. Positive correlation of SUV uptake and Glut1 expression in rat tumors was observed (Spearman rank correlation test, rs = 0.97, P < 0.01). Before RT, the SUV in rat tumor was 1.28 ± 0.31 and was decrease to 1. 00 ± 0.23 at the 3rd day and 0.18 ± 0. 10 at the 4th week after RT (F=15. 126, P<0.05). Before RT, the Glut1 in rat tumor was 0.2558 ±0.03 and was decrease to 0. 2320 ± 0. 01 at the 3rd day and 0. 1320±0.04 at the 4th week after RT. The amounts of tumor cell apopto-sis, degradation, and necrosis increased with time after RT. Conclusion Though FDG PET could monitor the therapeutic effect at the 3rd day after giving single dose of RT to rat lung tumor model, the optimal time was the the 4th week after treatment.     

FDA批准第一个用于治疗纤维肌痛的药物

美国食品与药品管理局(FDA)6月21日批准了第一个用于治疗纤维肌痛的药物Lyrica(prega-balin普瑞巴林)。这项批准是基于包括1800例病人的两个双盲对照临床研究的,该研究支持以每日300mg或450mg的Lyrica治疗纤维肌痛。研究表明Lyrica能减轻一些纤维肌痛患者的疼痛并改善其日常生活。Lyrica的批准被认为是一个重大的进步,但是在临床实验中,还是有一些病人在服用Lyrica后并没有好转。Lyrica最常见的副作用包括轻度到中度的眩晕和困倦。临床实验中也有视力障碍,体重增加,口干,手脚浮肿的报导。这些副作用似乎与剂量相关。Lyrica会削弱驾车能…     

针刺迎香治疗快速心律失常68例疗效观察

针刺迎香治疗快速心律失常６８例疗效观察马玉琛，隋速成，刘安才（解放军２５２医院，河北保定０７１０００）主题词心律失常／针灸疗法，心动过速．室上性／针灸疗法，心房纤颤／针灸疗法，穴．迎香１９９３年～１９９４年，我们在急诊病人中采用心电监护为主要观测手段...     

脑立体定向术治疗高血压脑出血经验与体会

目的：通过对我院3年来利用脑立体定向微创术治疗的78例高血压脑出血的临床病例，总结成功经验，以期进一步提高该手术治疗高血压脑出血的治疗效果。     

试论健康教育的人才开发

随着我国社会主义市场经济的发展，人们越来越认识到：知识和人才的重要。面临新技术的挑战，所谓竞争，即知识的竞争、人才的竞争。     

外治法治疗离心性环状红斑36例

外治法治疗离心性环状红斑３６例莒县中医院（２７６５００）陈长平李桂明李孟振关键词离心性环状红斑外治法疗效观察离心性环状红斑为一种反复发作的慢性环状红斑，可持续数年之久，我院自１９９３年以来，应用外治法治疗３６例，均获得显著疗效，现报告如下。１临床资料...     

甲硝唑、强的松合剂局部用药治疗根尖周炎、牙龈炎的方法及探讨

甲硝唑是治疗口腔炎症时一种常用的口服药，口服用药常出现较大的胃肠反应，强的松尽管有良好辅助抗炎能力．由于其固有的副作用也不易大量应用。笔者将甲硝唑和强的松片剂碾成粉混合应用于口腔的局部炎症，获得良好效果，现报告如下。     

肾脏恶性肿瘤动脉栓塞姑息治疗临床探讨（附22例病历）

目的：探讨动脉栓塞姑息治疗肾脏恶性肿瘤的临床价值。方法：收集整理共22例病历，经股动脉穿刺插管选择进入肾动脉，造影后施动脉栓塞治疗。结果：22例病历中，经肾动脉造影观察有20例取得满意疗效，2例因肿瘤血供少行经皮肾肿瘤穿刺硬化治疗。结论：动脉栓塞治疗肾脏恶性肿瘤方法可行，是肾脏恶性肿瘤姑息治疗的最佳选择。