原发性血小板增多症并发急性心肌梗死1例分析

对原发性血小板增多症并发急性心肌梗死1例分析如下。1病历摘要男，63岁。因胸痛20h入院，胸痛持续不缓解，伴喘气、呼吸困难，起病后4h在外院行心电图检查：窦性心律、急性广泛前壁心肌梗死（I,AVL，V1～V6导联水平上抬约0．4～0．9mV），给予尿激酶150万U静脉溶栓等治疗，胸痛、喘气缓解不明显，转入我院。既往无高血压、糖尿病、高脂血症、无吸烟等病史，偶尔饮酒。家族史无特殊。入院体检：T36．5℃，P90次／min，R22次／min，BP90／60mmHg，神志清楚，颈静脉充盈，双肺呼吸音粗，双中下肺可闻及湿性哕音。心界向左扩大，HR90次／min，心律齐，心脏各瓣膜听诊区未闻及杂音。     

颈动脉粥样硬化与不同类型冠心病的相关性分析

目的 了解冠心病患者颈动脉粥样硬化的发病率;分析冠心病患者颈动脉粥样硬化的相关危险因素;探讨冠心病患者颈动脉粥样硬化程度与冠状动脉粥样硬化程度的关系;总结不同类型冠心病患者颈动脉粥样硬化病理特点.方法 回顾性分析了228例经冠状动脉造影确诊为冠心病的病例冠状动脉造影结果 、颈动脉超声检测结果 及相关危险因素;根据颈动脉...     

颈动脉粥样硬化与不同类型冠心病的相关性分析

目的 探讨冠心病病人颈动脉粥样硬化程度与冠状动脉粥样硬化(CAAS)程度的关系及相关危险因素;总结不同类型冠心病患者颈动脉粥样硬化(CAS)病理特点.方法 回顾性分析228例经冠状动脉动脉造影确诊为冠心病的病例冠状动脉造影结果、颈动脉超声检测结果及相关危险因素;根据颈动脉是否有粥样硬化分为粥样硬化组及非粥样硬化组;根据WHO诊断标准将病例分为稳定型心绞痛组、不稳定型心绞痛组及心肌梗死组;根据冠状动脉造影结果将病例分为单支病变组(组A)、双支病变组(组B)、三支病变组(组C)及左主干组(组D);对颈动脉粥样硬化(CAS)程度进行积分处理.结果 发现228例冠心病病人中198例均有不同程度颈动脉粥样硬化,发病率86.8%;颈动脉粥样硬化(CAS)与高血压显著相关,与年龄、性别、体重指数、吸烟、嗜酒、高脂血症、高尿酸血症及糖尿病无明显相关;颈动脉粥样硬化(CAS)程度随冠状动脉粥样硬化(CAAS)的程度加重而加重,但仅仅一支病变组总斑块数显著低于左主干组(P＜0.05);稳定型心绞痛组的颈动脉等级积分、Crouse积分均低于不稳定型心绞痛组;稳定型心绞痛组颈动脉等级积分(grading integral)较急性心肌梗死组低,而Crouse积分高于急性心肌梗死组;稳定型心绞痛组的总斑块数、扁平斑数及软斑数均低于不稳定型心绞痛组及急性心肌梗死组,三组的硬斑数差异无统计学意义(P＞0.05).三组均未发现溃疡斑.结论 颈动脉粥样硬化与冠心病有相关性.

Abstract：

Objective To determine the relationship between the aggravation of CAAS and coronary atherosclerosis (CAS) ;and to summarize the pathologic character of CAAS of the patients with various coronary artery disease. Methods Review the result of coronary angiography and carotid artery ultrasonography and the related risk factors of the patients who were diagnosed as CAD through coronary angiography ( CAG). The patients were divided into the scleratheroma group and the non scleratheroma group. The patients were divided into stable angina pectoris( AP) group, unstable angina pectoris(UAP) group and acute myocardial infarction (AMI) group according to the criterion of coronary artery disease of WHO. The patients were divided into group A (coronary artery of single vessel lession) ,group B( coronary artery of double vessel lession ) , group C( coronary artery of triple vessel lession )and group D(left main vessel lession ).The aggravation of CAAS was graded. Results There were 198 patients with various CAAS among 228 patients with coronary artery disease ( 86. 8%). CAAS was much related with hypertension and non-related with age, sex, BMI, smoking, drinking, hyperlipoidemia, hyperuricosuria and diabetes mellitus. The aggravation of CAAS much graver with much graver CAS. But only the plaque number of Group A was more than Group D( P ＜0. 05). The grading integral and Crouse integral of CAAS of AP group was not remarkable less than UAP group. The grading integral of CAAS of AP group was less than AMI group and the Crouse integral of AP group was more. But there was no remarkable difference. The number of all plaque,plaque and plaque of AP group was not remarkable less than UAP group and AMI group. There was the plaque among the three group. Conclusion Carotid artery atherosclerosis (CAAS) is relative to coronary artery disease ( CAD).     

主动脉夹层患者死亡的危险因素分析

目的分析主动脉夹层患者死亡的危险因素分析,为降低主动脉夹层患者病死率作出指导。方法回顾性分析武汉亚洲心脏病医院2006年8月至2010年4月收治的571例主动脉夹层患者的临床资料,探讨各临床因素导致的病死率,并进行多因素分析,明确导致患者死亡的危险因素。结果单因素分析结果显示：不同Standford分型,有无家族心血管病史、吸烟史、并发症,及不同收缩压和治疗方式的病死率比较,差异有统计学意义（P〈0．05）;多因素非条件Logistic回93分析结果显示：Stanford分型A型、有家族心血管病史、有吸烟史、收缩压〈90mmHg及行手术治疗方式是影响主动脉夹层患者死亡的独立危险因素（P〈0．05）。结论Stanford分型A型、有家族心血管病史、有吸烟史、收缩压〈90mmHg及行手术治疗方式显著增加了主动脉夹层破裂的风险,是影响主动脉夹层患者病死的独立危险因素,对存在上述指征的患者应给予重点看护、治疗,以降低病死率,提高预后。     

脉络宁预防急性缺血性心脑血管病的临床观察

选择高血压病、糖尿病、高脂血症、冠心病、短暂性脑缺血发作（TIA）、陈旧性脑梗塞、陈旧性心肌梗塞患者876例。随机分2组,对照组应用基础治疗;观察组应用基础治疗加脉络宁疗法。脉络宁疗法：每年2－3月份和10－11月份各治疗1个疗程。观察2年,比较3组患者脑梗塞、心肌梗塞、心脏骤停的发生和再发率。结果：与对照组比较,观察组脑梗塞和心肌梗塞的发生率和再发率明显降低（P＜0．01及P＜0．05）。提示在基础治疗的同时,每年至少2个疗程应用脉络宁是降低缺血性心脑血管病急性事件发生和再发的一种安全有效的预防措施。