还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

五华县医疗单位1994年度消毒状况调查

五华县医疗单位１９９４年度消毒状况调查温兴章，钟仕强，何远先，刘超群，李安荣，曾梅湘《消毒管理办法》已贯彻实施多年，为更好地掌握我县医疗单位的消毒执行情况，我站于１９９４年５～１２月对６所县级医疗单位、２６所卫生院和２８３间集体、个体诊所进行了消毒状...     

还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

带桡动脉茎突返支骨膜瓣移植治疗腕舟骨骨不连

自1 995～2 0 0 2年对1 5例腕舟骨骨不连采用带桡动脉返支骨膜瓣移植治疗,以改善腕舟骨血运、促进骨折愈合,疗效满意。1　临床资料1 1　一般资料　1 5例中,男1 1例,女4例,年龄1 9～4 2岁,平均2 6 6岁。左侧3例,右侧1 2例。跌倒伤9例,车祸伤5例,运动伤1例。所有病例均有腕关节疼痛,握力下降,患侧鼻咽窝有明显压痛,腕关节背伸及桡偏时疼痛。X线片示:骨折线清晰且增宽,断端硬化伴囊性改变。所有病例病程均在6个月以上,此前非手术治疗石膏固定8例,误诊2例,手术切开复位内固定5例。1 2　手术方法　臂丛麻醉下不驱血气囊止血带下手术,于桡骨远…     

步长脑心通配合牵引手法治疗椎动脉型颈椎病疗效观察

目的：观察步长脑心通口服配合牵引手法综合治疗椎动脉型颈椎病的疗效。方法：治疗组采用步长脑心通口服配合牵引手法综舍治疗，对照组采用牵引加复方丹参静脉滴注。结果：治疗组较对照组有非常显著性差异。结论：步长脑心通胶囊配合牵引手法治疗椎动脉型颈椎病较传统使用复方丹参静脉滴注效果为佳。     

短暂性脑缺血发作患者ABCD3-I评分与责任血管病变特点的关系及预后分析

目的 探讨短暂性脑缺血发作（TIA）患者ABCD3-I评分与责任血管病变特点的关系及预后分析。方法 选取2015年1月—2018年6月于滁州市中西医结合医院脑病科收治的112例TIA患者,采用ABCD3-Ⅰ评分进行危险分层,分析不同危险分层与责任血管病变的关系,另通过Logistic回归模型探讨相关危险因素,随访患者3个月,统计其脑梗死发病率。结果 随着ABCD3-Ⅰ评分的增高,颅内动脉狭窄率呈升高趋势（P?<0.05）,颈部血管狭窄呈下降趋势（P?<0.05）;颈部血管超声显示,内膜增厚（44.82%）是低危组颈部血管主要病理改变,中高危组主要表现为软斑形成（35.53%）;经颅多普勒检查提示低危组患者以脑动脉弹性降低为主（52.00%）,中、高危组均以颅内血管血流速度异常为主（60.53%和72.73%）;低、中危组主要表现为单支血管病变（85.19%和62.50%）,而高危组主要表现为多支血管病变（79.41%）,同时各组供血动脉病变数比较,差异有统计学意义（P?<0.05）;Logistic回归分析发现,责任血管狭窄率≥50% [OlR=3.425（95% CI：1.402,8.956）,P?=0.008]、单侧肢体无力[OlR=4.612（95% CI：1.572,12.876）,P?=0.006]和不稳定斑块[OlR=3.243（95% CI：1.276,7.124）,P?=0.001]是90?d内进展为脑梗死的独立危险因素（P?<0.05）。各组卒中发生率比较,差异有统计学意义（P?<0.05）。结论 TIA患者ABCD3-I评分能够反映患者血管的狭窄程度、斑块性质及血管病变支数,结合危险因素能够早期防治脑梗死。     

结核病患者外周血CD4+CD25+ T淋巴细胞凋亡及FOXp3表达情况观察

目的初步观察分离培养的结核病患者外周血CD4+CD25+ T淋巴细胞凋亡及其表面特征性标志物FOXp3的表达情况。方法采用密度梯度离心法及尼龙棉柱法分离结核病患者外周血T淋巴细胞,磁性细胞分离器(MACS)分离得到CD4+CD25+ T淋巴细胞,体外培养72 h后分别利用电镜及流式细胞仪观察、检测各分组(结核病组、健康对照组)细胞的凋亡率及FOXp3的表达。结果 MACS可成功分离CD4+CD25+ T淋巴细胞,纯度可达81.1%～84.7%。结核病组较健康对照组外周血CD4+CD25+ T淋巴细胞计数增多,凋亡率增加,FOXp3表达增高(P均<0.05)。结论 FOXp3高表达的CD4+CD25+ T淋巴细胞在结核病的免疫调节过程中起着重要作用,并且与CD4+CD25+ T淋巴细胞的凋亡密切相关。     

结核性胸水见类上皮细胞1例

正结核性胸膜炎为常见病,按病理解剖分为干性胸膜炎和渗出性胸膜炎两类。当渗出性胸膜炎时,胸腔会出现数量不等的积液,俗称胸水。结核性胸水细胞学的报道多以淋巴细胞为主,其他情况报道较少,现报告1例结核性胸水检出类上皮细胞。1临床资料患者,男,72岁,主因"胸闷、咳嗽7 d"于2016年2月2日入院。患者7 d前受凉后出现咳嗽、咳痰,痰色白,量少,不易咳出,伴胸闷、乏力,活动后胸闷明显,无寒战发热,无胸痛     

颈椎前路手术治疗颈椎骨折合并高位截瘫21例围术期护理体会

2006年以来,我们采用颈椎前路手术治疗21例颈椎骨折合并高位截瘫患者,经精心护理,效果满意。现将围术期护理体会报告如下。1临床资料本组21例,男14例,女7例,20~74岁。车祸伤8例,高处摔伤13例,其中完全性截瘫7例,不完全截瘫14例,卧床时间30~78d。2护理2.1术前护理2.1.1心理护理患者因突然瘫痪、脊髓功能受损,思想负担重,加上手术难度大、时间长,患者常产生焦虑、紧张、恐惧心理,担心手术效果。护士应耐心向患者解释手术的目的是为了控制病情发展,解除压迫植骨融合达到固定融合,使患者愉快地接受手术治疗,并请做同类手术的患者现身说法,介绍手…     

老年高血压患者颈动脉粥样硬化与血尿酸水平的相关性研究

动脉粥样硬化是一种损害全身大、中动脉内膜的慢性疾病,可导致许多重要器官尤其是心、脑、肾等结构和功能改变,最初是内膜中层厚度(intimal medialthickness,IMT)增厚内膜粗糙,继而斑块形成,管腔狭窄.病变的严重程度受高血压、血脂、血糖、年龄、吸烟等心血管多种危险因素的影响.前期研究表明尿酸(UA)是又一重要危险因素,本研究旨在了解血UA在老年高血压患者颈动脉粥样硬化形成中的作用,以期更好的控制和防治动脉粥样硬化,预防心脑血管事件的发生.