经腹行Heller加改良Dor手术治疗贲门失弛症的临床疗效观察

目的 评价经腹行Heller术加改良Dor术治疗贲门失弛症的疗效.方法 经腹行Heller加改良Dor手术治疗贲门失弛症病人33例,其中18例术前及术后均行食管测压检查及24 h食管pH监测,对术前及术后食管下括约肌静息压(LESP)及24 h内食管反流次数、最长反流时间(min)、pH＜4.0时间(min)、pH＜4.0时间百分比(%)等指标进行统计学分析.结果 术后1例仍有吞咽困难,其余32 例症状明显好转.术后1个月复查食管测压检查及24 h食管pH监测,LESP值较术前明显下降(P＜0.001).24 h反流次数、最长反流时间、pH＜4.0时间、pH＜4.0时间百分比等指标较术前均有下降,差异均有统计学意义(P＜0.05).随访30例(90.9%,30/33例),其中症状消失22例(73.3%,22/30例),改善8例(26.7%,8/30例);术前经24 h食管下端pH监测证实其中3例(16.7%,3/18例)存在不同程度的胃食管反流,术后随访均无反流性食管炎发生.结论 经腹行Heller加改良Dor手术除能明显改善贲门失弛症的症状外,还能有效防止术后可能带来的胃食管反流,且手术操作较简单,创伤小,并发症少.

Abstract：

Objective To evaluate the effect of curing achalasia by transabdominally Heller-Dor operation. Methods To summarize 33 cases of achalasia treated by transabdominally Heller-Dor procedure and visit them postoperatvely. 18 patients receive pre- and post-operativemanometry and 24-hour-pH monitoring. The parameters including reflux frequency 、the longest lasting-time of reflux 、the total time(min) of pH ＜4.0 and the percentage( % ) of time of pH ＜4.0 were recorded and compared using statistical mothods. Results Symptom was significantly improved in 32 patients after surgery, while 1 patient remained dysphasia as pre-operative. The LESP, the reflux frequency、the longest lasting-time of reflux 、the total time(min) of pH ＜ 4.0 and the percentage ( % ) of time of pH ＜ 4.0 also declined after operations ( P ＜ 0. 05 ). 30 patients were followed up,22 (73.3% ,22/30) were cured and 8 had mild sypmtom. Reflux did not detected in 3 cases( 16.7% ,3/18 ) with preoperative reflux. Conclusion Transabdominally Heller-Dor operation could dramadically alleviate the symptoms of patients with achalasia, moreover, it could especially prevent the postoperative-reflux, and with the advantages of simple operations, little traumas.     

经腹改良Heller术联合Dor术治疗贲门失弛缓症疗效观察

目的观察经腹行改良Heller术联合Dor术治疗贲门失弛缓症的疗效。方法经腹行改良Heller术联合Dor术治疗贲门失弛缓症患者33例。结果术后32例症状明显好转,1例仍有吞咽困难,术后1个月食管下括约肌静息压（LESP）、24 h反流次数、最长反流时间、pH〈4.0时间、pH〈4.0时间百分比较术前均有下降（P均〈0.05）。30例患者获1-6 a随访,症状消失22例,改善8例。3例术前存胃食管反流者术后随访均无反流性食管炎发生。结论 经腹行改良Heller术联合Dor术能明显改善贲门失弛缓症的症状,有效防止术后胃食管反流,且手术创伤小,并发症少。