T_3占优势Graves病22例临床分析

T_3占优势 Graves 病患者其特征为,由于抗甲状腺药物治疗过程中,血清 T_3持续升高,T_4正常,T)_3/T_4比率(ng/μg)大于20。我们随访22例,接受药物治疗18～28个月,观察2年,16例复发。复发时间乎均停药8.8个月。其中8例复发者作甲状腺次全切除术,术后甲状腺功能恢复正常,血清 T_3/T_4比率均小于20。T_3占优势甲状腺机能亢进患者有较高的血清 TSH 受体抗体活性,与甲状腺 T_4 5′-脱碘酶活性有关.药物治疗缓解率低,以选用手术或同位素治疗为佳.     

中西医结合治疗晚期原发性肝癌57例

从 1990年 1月～ 2 0 0 0年 12月 ,笔者采用中西结合治疗晚期原发性肝癌 5 7例 ,疗效满意 ,并与单用西药治疗的 5 1例进行对照观察 ,现报告如下。1　临床资料两组 10 8例均系我院住院病人 ,且符合晚期 (Ⅲ期 )原发性肝癌的诊断标准。治疗组 5 7例中 ,男 42例 ,女 15例 ;年龄最大者 71岁 ,最小者 19岁 ,平均 5 5岁 ;从明确诊断至入院治疗时间最长者 4个月 ,最短者不足 1个月 ,平均 2 .5个月。对照组 5 1例中 ,平均年龄 5 4岁 ;平均发病时间为 2 .4个月 ;且治疗中均不愿内服中药。2　治疗方法2 .1　对照组　根据病情分别予以保肝、支持、对症…     

甲状腺机能减退症的脂类代谢——附50例分析

本文报道甲减50例(男10例,女40例),年龄16～63岁,病程3个月～20年,其中亚临床型甲减10例,轻型10例,重型30例。伴心绞痛5例,心肌梗塞1例,主动脉硬化8例,眼底动脉硬化16例。甲减伴高胆固醇血症36例,占72％,伴高甘油三酯(TG)血症12例,占24％。重型甲减血清总胆固醇(TC)升高尤为显著,仅重型甲减TG增高而HDL-Ch降低;临床型甲减     

地西泮佐山莨菪碱滴鼻治疗小儿高热惊厥

目的　观察地西泮佐小剂量山莨菪碱滴鼻治疗小儿高热惊厥的临床疗效 ,探讨其对小儿高热惊厥急救的实用价值。方法　随机把 87例高热惊厥患儿分为治疗组 47例 ,对照组 40例。其中治疗组先用山莨菪碱溶液 0 2 5mg滴入患儿鼻腔 ,随后按每千克体重 0 2mg地西泮溶液滴鼻 ;对照组用同厂同批号地西泮按每千克体重 0 3mg肌注做对比。结果　地西泮佐小剂量山莨菪碱滴鼻能快速控制小儿高热引起的惊厥发作 ,显效率与总有效率明显优于对照组(P <0 0 5 )。结论　地西泮佐小剂量山莨菪碱滴鼻给药是控制小儿高热惊厥的又一方便途径 ,在院前急救及难于建立静脉通道的情况下能发挥安全速效的作用     

50例甲状腺机能减退症的脂类代谢分析

50例甲减患者中,高胆固醇血症者占72%。24%患者的甘油三酯高于正常,以重型甲减较显著。重型甲减 HDL-Ch 明显降低,临床型甲减 HDL_2低于正常,且血清T_3与 HDL、HDL_2和HDL_2/HDL_3比值有显著相关性。本文资料提示,甲减患者随着病情加重,脂类代谢紊乱渐严重,甲状腺制剂替代治疗,持续有效地降低血脂,可望阻止动脉粥样硬化的进展,甚至促进病变消退。     

NONINVASIVE METHOD FOR DETECTING THYROID FUNCTION R-p TIME INTERVAL TECHNIQUE

We used a, seif-designed instrument to cvaluate thyroid function. With this instrument the R-p time interva.ls wer'e mea.sured from the o.nset of R wave on ECG to the onset of the pulse wave taken from electrodes placed on the fore- head. This interval was related to myocardial contra.ctility and could be changed by circulating thyroid hormones. The range of R.-p time in- terval in 50 normal subjects was, 121-144 msec (132+5.8). In 47 cases of hyperthyroidism, this time interval wa.s shortened t0 98-119 msec <10,8.5+5..6) and in 18 cases of hypothyroidism, it was prolonged t0 144-179 msec (16.01+8.7). There was an exponential correlation between R-p time intervals and the concentrations of serum T3, T4. This method could be used as a screening test, for estimating the thyroid functional status and as an index t,o guide medication during the course of treatment of hyper- and hypothyroidism.     

PERIPHERAL AND AUTONOMIC NERVE FUNCTION. TESTS IN EARLY DIAGNOSIS OF DIABETIC NEUROPATHY CORRELATION BETWEEN MOTOR NERVE CONDUCTION VELO- CITY AND FASTING PLASMA GLUCOSE

This paper reports the application of peri- pheral motor ne'rve conduction velocity (MNCV) determination and 6 noninvasive autonomic functional tests for the early diagnosis of dia- betic neuropathy. Among the 150 cases of new- ly discovered diabetics investigated during ex- tensive survey in Sha.nghai, 135 cases of tlia.- betic neuropathy were diagnosed. In this group, patients with both neurologic symptoms and signs were found in 56 cases, only symptoms with no signs in 50, only sign.s with no symp- toms in 8 and both symptoms and signs absent but diagnosis. based on special tests in 21. The motor nerve conduction velocity of the median n., ulnar n., and fibular n. were ascer- tained on JD Type II electromyography. The velocity was found to be significantly slower in diabetics with neuropathy than the control group. H-reflex and tibial n. Iatency were found to be prolonged in diabetics as compared with the control group. There is negative cor- relation 'oetween the MNCV and fa.sting plas- ma glucose and positive correla.tion between the H-reflex and fasting plasma glucose, indicating that hyperglycemia may be closely related to the pathogenesis of diabetic neuropathy. No correlation was found between the MNCV, age and duration of d[iabetes. For early diagno,sis of diabetic neuropathy, besides the symptoms and signs, motor nerve conduction velocity and 4 0f the 6 noninvasive autonomic ne'rve function test are valuable and reliable diagnostic procetlures. Differential diagnosis from other causes of neuropathy is also emphasized.     

糖尿病患者在治疗中的肾功能改变

糖尿病肾病为糖尿病的严重并发症之一。本文对79例确诊为糖尿病肾病者分组进行研究,在纠正高血糖的治疗基础上,加用丹参和潘生丁治疗,试图研究糖尿病肾病患者纠正代谢紊乱后的肾脏功能改变,以及活血化瘀药物对糖尿病肾病的疗效。     

益气活血通络法化裁治疗缺血性中风恢复期51例

作者采用益气活血法 ,以补阳还五汤加减治疗缺血性中风恢复期 5 1例为治疗组 ,并与单纯用西药常规治疗的 31例为治疗组进行对比观察 ,结果治疗组总有效率为 94.3% ,对照组总有效率为 82 % ,两组疗效有显著性差异 (P <0 .0 5 )。