全文获取类型
收费全文 | 9662篇 |
免费 | 443篇 |
国内免费 | 63篇 |
专业分类
耳鼻咽喉 | 44篇 |
儿科学 | 280篇 |
妇产科学 | 113篇 |
基础医学 | 1133篇 |
口腔科学 | 137篇 |
临床医学 | 643篇 |
内科学 | 2469篇 |
皮肤病学 | 199篇 |
神经病学 | 576篇 |
特种医学 | 499篇 |
外科学 | 1841篇 |
综合类 | 28篇 |
预防医学 | 255篇 |
眼科学 | 202篇 |
药学 | 728篇 |
中国医学 | 68篇 |
肿瘤学 | 953篇 |
出版年
2023年 | 35篇 |
2022年 | 62篇 |
2021年 | 181篇 |
2020年 | 100篇 |
2019年 | 149篇 |
2018年 | 175篇 |
2017年 | 157篇 |
2016年 | 175篇 |
2015年 | 193篇 |
2014年 | 259篇 |
2013年 | 313篇 |
2012年 | 467篇 |
2011年 | 540篇 |
2010年 | 272篇 |
2009年 | 278篇 |
2008年 | 440篇 |
2007年 | 542篇 |
2006年 | 494篇 |
2005年 | 555篇 |
2004年 | 591篇 |
2003年 | 547篇 |
2002年 | 518篇 |
2001年 | 342篇 |
2000年 | 363篇 |
1999年 | 328篇 |
1998年 | 107篇 |
1997年 | 95篇 |
1996年 | 73篇 |
1995年 | 62篇 |
1994年 | 51篇 |
1993年 | 49篇 |
1992年 | 148篇 |
1991年 | 142篇 |
1990年 | 159篇 |
1989年 | 132篇 |
1988年 | 134篇 |
1987年 | 114篇 |
1986年 | 108篇 |
1985年 | 112篇 |
1984年 | 62篇 |
1983年 | 79篇 |
1982年 | 30篇 |
1979年 | 61篇 |
1978年 | 36篇 |
1975年 | 34篇 |
1974年 | 27篇 |
1971年 | 23篇 |
1970年 | 33篇 |
1969年 | 23篇 |
1968年 | 23篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Shigeko Tanaka Minoru Yoshiyama Yukihiro Imanishi Koichi Nakahira Takashi Hanaki Yukari Naito Mizue Imai Masahiro Tanaka 《Magnetic resonance in medical sciences》2006,5(4):207-210
One diagnostic criterion for metabolic syndrome is obesity from the accumulation of visceral fat; others include abdominal circumference and area of visceral fat as measured by computed tomography (CT) at the umbilical level. We evaluated visceral fat using frequency-selective excitation magnetic resonance (MR) imaging SPAIR (spectral attenuation with inversion recovery) water suppression THRIVE (3D T1-high resolution isotropic volume examination). Fifty of 70 slices with 2-mm interval were used to render and measure volume of visceral fat ranging within 10 cm of the umbilicus; the area of visceral fat at the umbilical level was also measured. Imaging was completed using breath hold within 14 s. Image processing was easier than using CT. 相似文献
5.
T. Yoshikawa H. Tohyama H. Enomoto H. Matsumoto Y. Toyama K. Yasuda 《Knee surgery, sports traumatology, arthroscopy》2006,14(9):804-810
The aim of this study was to clarify vascular endothelial growth factor (VEGF) expression and angiogenesis in the patellar tendon (PT) autograft in the early phase after anterior cruciate ligament (ACL) reconstruction using a rabbit model. The right knees of 30 Japanese white rabbits underwent ACL reconstruction using the medial third of the PT complex. We evaluated the grafted tendon at 1, 2, 3, 4, and 8 weeks after ACL reconstruction by immunohistology for proliferating cell nuclear antigen, VEGF, and CD31, which is a marker for vascular endothelial cells. At week 1 , few cells were observed at the midsubstance of the grafted tendon. A number of proliferating cells were observed at the surface area of the PT graft 2 weeks after graft transplantation, while no vessel formation was observed in the graft at the same time. VEGF was highly expressed 2-3 weeks postoperatively. Vessel formation in the PT graft increased with time from 3 to 8 weeks after ACL reconstruction. The rates of proliferating cells and VEGF-expressing cells decreased with time from 3 to 8 weeks. This study has suggested that VEGF is involved in the graft remodeling process particularly at the early phase after ACL reconstruction. 相似文献
6.
Keiichiro Kume Masahiro Yamasaki Ichiro Yoshikawa Makoto Otsuki 《Digestive endoscopy》2006,18(3):218-220
Background: Although bleeding is an unavoidable complication of endoscopic submucosal dissection (ESD), endoscopic hemostasis using an insulation‐tipped electrosurgical knife (IT) knife is impossible because an insulator is mounted at the tip of the knife. We have developed a new type of hood which could perform both coagulation and irrigation simultaneously. Methods: Our new device was fabricated by drilling a side hole in the cap portion of a conventional transparent hood followed by attaching a machined papillotomy knife to the exterior surface of the hole. Results: Our new hood was useful for hemorrhage during ESD using IT knife. Conclusions: With this method, endoscopic hemostasis using IT knife is easy, as hemostatic procedure can be performed under irrigation and coagulation using conventional endoscopy. 相似文献
7.
Kensaku Maeda Kenichi Yasunari Eisuke F Sato Junichi Yoshikawa Masayasu Inoue 《Hypertension research》2003,26(12):999-1006
The involvement of oxidative stress in polymorphonuclear leukocytes (PMN) in the pathogenesis of hypertension remains to be elucidated. We analyzed the generation of reactive oxygen species (ROS) by the circulating and peritoneally infiltrating PMN from spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY). Flow cytometric analysis revealed that ROS generation by PMN from SHR was higher than that from WKY before (at 6 weeks of age) and after (at 16 weeks of age) the onset of hypertension. In vivo, ROS generation by PMN from SHR, but not that by PMN from WKY, was significantly suppressed by 10-week treatment with 50 mg/kg/day carvedilol, and this treatment did not affect blood pressure. Western blotting analysis revealed that protein kinase C alpha (PKCalpha), but not PKCbetaI or betaII, was activated more strongly in PMN from SHR than in PMN from WKY. Furthermore, expression of p47phox of nicotinamide adenine dinucleotide phosphate oxidase, but not of p67phox, in PMN from SHR was higher than that in PMN from WKY. These results suggest that ROS generation by PMN is principally enhanced in SHR through activation of PKCalpha and p47phox. 相似文献
8.
Takayuki Takeichi Hideaki Okajima Hiroko Suda Shintarou Hayashida Hironori Iwasaki Manuel Zeledon Ramirez Mikako Ueno Katsuhiro Asonuma Yukihiro Inomata 《Liver transplantation》2005,11(10):1285-1288
Congenital absence of the portal vein (CAPV) is a rare malformation of the splanchnic venous system. Although CAPV is usually detected in the pediatric age group, our patient was a 35-year-old woman. She had been diagnosed with CAPV in 1996 when she was 27 years old. In 1998, she was placed on hemodialysis due to chronic renal failure. After several episodes of encephalopathy in 2002, liver transplantation (LT) was recommended to her and her family. Since there was no suitable living donor candidate, she was put on the waiting list for a deceased donor liver transplant in Japan. In 2004, her ammonia level increased to around 300 microg/dl, and she went into a coma lasting for three days. After recovering from this event, she underwent a living domino transplantation using a whole liver donated by a familial amyloid polyneuropathy (FAP) patient. Her portal vein, which had drained directly into the inferior vena cava (IVC), was transected together with a cuff of the IVC wall and anastomosed to the graft liver portal vein in an end-to-end fashion. In conclusion, liver transplantation proved to be a safe and effective way to save this patient and improve her quality of life. 相似文献
9.
M Fukumizu T Kurokawa H Yoshikawa S Hanaoka 《No to hattatsu. Brain and development》1991,23(6):617-622
A seven-month-old girl with atypical West syndrome with pedaling automatism was reported. She started to have early infantile epileptic encephalopathy with suppression-burst (EIEE) at age 14 days followed by infantile spasms at 3 months of age. She began to have spasms with automatism at 4 month, mainly consisting of pedaling movements of both feet associated with tonic spasms of upper extremities and writhing of trunk. Ictal EEG showed irregular slow waves with occasional spikes predominantly over the right hemisphere mixed with artifacts. Interictal EEG during sleep showed suppression-burst patterns. Cerebral atrophy and microcephaly were revealed on brain CT, immature myelination on MRI and decreased blood flow in the frontal, temporal, and parietal lobes on the right on PET scan. Pedaling automatism is rare in infancy and its clinical significance was discussed in relation to West syndrome and complex partial seizures. 相似文献
10.
H Ikenaga T Ogihara S Iyori S Kou H Yoshikawa M M Okura 《Postgraduate medical journal》1989,65(768):761-764
A case of a young Japanese woman with long-standing ulcerative colitis complicated by preinfarction angina due to Takayasu's aortitis is presented. Successful emergency aorto-coronary bypass operation was performed. Whether the association of these two diseases can be explained by a common mechanism is discussed. 相似文献