Renal cryoablation – a practical guide for interventional radiologists

Renal cryoablation is a treatment option for early stage renal cell carcinomas with excellent oncological outcomes and low morbidity. This review outlines the technique of renal cryoablation and provides a guide for interventional radiologists on setting up an integrated service within a renal cancer network multidisciplinary setting. Patient selection and preparation, together with the technical aspects which ensure optimal oncological outcomes and avoid collateral damage to adjacent organs are highlighted.     

An unexpected case of venous and pulmonary thrombo-embolism in a patient treated with thalidomide for refractory erythema nodosum leprosum: a case report

Recent literature reports an increased incidence of venous thrombosis following thalidomide use in the treatment of diseases with disease-related thrombotic risks such as malignancy, as well as concomitant use with chemotherapy and/or systemic corticosteroids. We report a case of deep vein thrombosis (DVT) and pulmonary embolism (PE) following thalidomide use in a patient with erythema nodosum leprosum (ENL) reaction who was concurrently treated with prednisolone, as well as a review of relevant literature.     

Effect of Hepatic Perfusion on Microwave Ablation Zones in an Ex Vivo Porcine Liver Model

Purpose

To compare the size of ablation zones derived from nonperfused ex vivo livers with ablation zones created using an ex vivo perfused porcine liver model.

An Infant Born to a Mother with Gestational Diabetes Presenting with 49,XXXXY Syndrome and Renal Agenesis-A Case Report

49,XXXXY is a rare sex chromosome polysomy with an incidence of 1 in 85 000 male births. It has a characteristic triad of mental retardation, skeletal malformation and hypogonadism. This is the first case report of a child with 49,XXXXY syndrome and renal agenesis. This child was referred for genetic testing at 14 years of age due to facial dysmorphism and hypergonadotropic hypogonadism. He had coarse facial features, cryptorchidism of the right testis, genu valgus deformities, and patent ductus arteriosus which are known associations of 49,XXXXY syndrome. He also had agenesis of the right kidney, hydronephrosis of the left kidney with hydroureter which is not a known association of 49,XXXXY syndrome. The patient was the offspring of a mother with gestational diabetes. There is a strong correlation between maternal diabetes and congenital anomalies, especially renal and cardiovascular anomalies. Additionally, it has been noted that gestational diabetes increases the incidence of chromosomal aneuploidies. The teratogenic effects of maternal diabetes during embryogenesis may be the causative factor for the final phenotype of 49,XXXXY syndrome and renal agenesis.Conflict of interest:None declared.     

Long-term experience of immediate implant loading using DenTi implants. Part 1. Material, methods and experience in immediate loading of DenTi implants

Immediate loading of dental implants have been widely used to retain and support crossarch partial dentures. Normally 3-6 months after implantation complete osseointegration is established, this period may be shortened with immediate loading of implants. The purpose of this study was to evaluate the factors that may influence the long-term success of immediate implant loading. The immediate loading technique with DenTi implants was introduced 12 years ago, and during this period the clinical results have been followed up on 257 DenTi implants in 83 patients. 62 patients and with 263 implants placed with submerged technique were recruited into the control group. The retrospective long-term follow-up examination has revealed that the success rate of DenTi implants with traditional two stage surgery was 97.4%. The success rate of DenTi implants with immediate loading was 95.71%. According to the date of the success rata and prognosis of immediate loaded implants are comparable to the traditional two stage submerged implants.     

Effects of Pollution on Health of Residents in an Industrial Area in Sri Lanka

The authors conducted a cross-sectional comparative prevalence study to evaluate the effect of pollution on individuals who lived in an industrial zone in Sri Lanka. In this study, 81 male and female children who were 1-12 yr of age and 158 adults (51 males, 107 females) in the industrial zone were matched with 73 children (32 males, 41 females) and 146 adults (58 males, 88 females), respectively, who lived in a nonindustrialized area and whose ages were similar to those of the exposed individuals. The authors used a pretested questionnaire and a detailed clinical examination, including peak expiratory flow rate measurements, to assess the prevalence of illness. Children in the industrial area were 2.3 times more likely to have unexplained episodic cough (95% confidence interval [Cl] = 0.98, 10.3) and 2.8 times more likely to have rhinitis (95% Cl = 1.1, 7.1). The adult population was 2.1 times more likely to have unexplained episodic cough (95% Cl = 1.13, 7.09), 3.7 times more likely to have unexplained headaches (95% Cl = 2.2, 6.3), and adults had a significantly greater reduction in expiratory flow (peak expiratory flow rate = 446 - 92x [industrial area] + 91 x [male] - 0.8x [years lived in the area]).