全文获取类型
收费全文 | 787篇 |
免费 | 60篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 21篇 |
儿科学 | 16篇 |
妇产科学 | 5篇 |
基础医学 | 104篇 |
口腔科学 | 51篇 |
临床医学 | 82篇 |
内科学 | 227篇 |
皮肤病学 | 7篇 |
神经病学 | 18篇 |
特种医学 | 98篇 |
外科学 | 81篇 |
综合类 | 28篇 |
一般理论 | 4篇 |
预防医学 | 43篇 |
眼科学 | 6篇 |
药学 | 44篇 |
肿瘤学 | 40篇 |
出版年
2023年 | 8篇 |
2022年 | 8篇 |
2021年 | 12篇 |
2020年 | 5篇 |
2019年 | 5篇 |
2018年 | 5篇 |
2017年 | 6篇 |
2016年 | 8篇 |
2015年 | 13篇 |
2014年 | 12篇 |
2013年 | 15篇 |
2012年 | 21篇 |
2011年 | 27篇 |
2010年 | 20篇 |
2009年 | 18篇 |
2008年 | 25篇 |
2007年 | 19篇 |
2006年 | 52篇 |
2005年 | 33篇 |
2004年 | 26篇 |
2003年 | 25篇 |
2002年 | 18篇 |
2001年 | 24篇 |
2000年 | 28篇 |
1999年 | 31篇 |
1998年 | 18篇 |
1997年 | 11篇 |
1996年 | 21篇 |
1995年 | 18篇 |
1994年 | 18篇 |
1993年 | 12篇 |
1992年 | 16篇 |
1991年 | 24篇 |
1990年 | 17篇 |
1989年 | 24篇 |
1988年 | 22篇 |
1987年 | 23篇 |
1986年 | 24篇 |
1985年 | 23篇 |
1984年 | 13篇 |
1983年 | 12篇 |
1982年 | 5篇 |
1981年 | 14篇 |
1980年 | 7篇 |
1979年 | 6篇 |
1977年 | 8篇 |
1976年 | 9篇 |
1975年 | 7篇 |
1974年 | 8篇 |
1968年 | 13篇 |
排序方式: 共有875条查询结果,搜索用时 88 毫秒
1.
G R Westerman J B Norton E A Kiel S H Van Devanter 《The Annals of thoracic surgery》1987,44(2):154-158
Double-outlet right ventricle and severe systemic outflow tract hypoplasia comprises a subset of patients in whom total correction or palliation requires complex surgical procedures in the neonatal period. Our experience with 3 patients illustrates the difficulties associated with treatment and suggests possible surgical options for this otherwise lethal variant of the Taussig-Bing syndrome. 相似文献
2.
3.
4.
S T Westerman M B Fine L Gilbert 《The Journal of the American Osteopathic Association》1990,90(10):926-928
Aerotitis, an acute inflammation of the middle ear caused by the difference in air pressure between the airplane cabin and the middle-ear space, is becoming more common in the United States as our society becomes increasingly mobile. We describe a case in which a 33-year-old woman with a resolving upper respiratory tract infection and mildly blocked eustachian tubes flew on a business trip. During ascent, her ears became blocked. This blockage was partially alleviated by a Valsalva's maneuver. On descent, however, her ears became severely blocked, she experienced intense pain, and her tympanic membranes ruptured. She became nauseated and vomited. Her hearing became significantly diminished and she experienced vertigo. On landing, she was taken to a local emergency room and treated with penicillin and antivertiginous medication. Subsequent otologic evaluation revealed severe permanent sensorineural hearing loss. The vestibular symptoms lasted several months. She now requires hearing aids on a permanent basis. Suggestions are presented for prevention and treatment of aerotitis. 相似文献
5.
A Golz S T Westerman L M Gilbert H Z Joachims A Netzer 《The Journal of laryngology and otology》1991,105(12):987-989
Although middle ear effusion was once described as the most common cause of vestibular disturbance in children, the association between glue ear and symptoms of dysequilibrium has never been quantified objectively. In this study the effect of middle ear effusion on the vestibular system of the inner ear was studied in a select group of children suffering from long lasting effusion in the middle ear with no evidence of infection at least one year prior to the study. The results were compared with results obtained from otitis free children, as well as from examinations of children after the insertion of ventilating tubes. The results of this study confirm the assumption that middle ear effusion has an adverse effect on the vestibular system, which can be resolved following the insertion of ventilation tubes. This effect may also contribute to the adverse effect that otitis media has on a child's development. 相似文献
6.
T M Egan J H Westerman C J Lambert F C Detterbeck J T Thompson M R Mill B A Keagy L J Paradowski B R Wilcox 《The Annals of thoracic surgery》1992,53(4):590-5; discussion 595-6
Since January 1990, we have performed 29 isolated lung transplantations in 28 patients with end-stage lung disease (12 single, 16 bilateral). Recipient diagnoses were: cystic fibrosis (11), chronic obstructive pulmonary disease (6), pulmonary fibrosis (6), eosinophilic granulomatosis (1), postinfectious lung disease (1), adult respiratory distress syndrome (1), and primary pulmonary hypertension (2). There have been four deaths, two in patients with pulmonary fibrosis and two in patients with primary pulmonary hypertension. Four patients have undergone transplantation while on ventilatory support for respiratory failure (2 with cystic fibrosis, 1 having redo lung transplantation with cystic fibrosis, and 1 with adult respiratory distress syndrome); all of these have survived. Six patients required cardiopulmonary bypass, which was associated with increased transfusion requirement. All patients 2 months after discharge have returned to an active life-style, except for 2 patients who currently await retransplantation. Preoperative pulmonary rehabilitation has resulted in significant improvement in exercise performance in all patients. Immunosuppression consists of cyclosporine, azathioprine, and antilymphoblast globulin (University of Minnesota), withholding systemic steroids in the early postoperative period. We have employed bronchial omentopexy in all but four transplants; there has been one partial bronchial dehiscence, two instances of bronchomalacia requiring internal stenting, and one airway stenosis. Cytomegalovirus disease has been seen frequently (15 cases), but has responded well to treatment with ganciclovir. Other complication shave included one drug-related prolonged postoperative ventilation, thrombosis of a left lung after bilateral lung transplantation requiring retransplantation, five episodes of unilateral phrenic nerve palsy after bilateral lung transplantation (4 resolved), and the requirement of massive transfusion (greater than 10 units) in 5 patients.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
7.
8.
9.
Immunoblot reactivity of polyclonal and monoclonal antibodies with periplasmic flagellar proteins FlaA1 and FlaB of porcine Serpulina species.
下载免费PDF全文
![点击此处可从《Clinical and Vaccine Immunology : CVI》网站下载免费的PDF全文](/ch/ext_images/free.gif)
L N Fisher G E Duhamel R B Westerman M R Mathiesen 《Clinical and Vaccine Immunology : CVI》1997,4(4):400-404
The periplasmic-flagellum (PF) proteins of Triton X-100-soluble and Triton X-100-insoluble sodium dodecyl sulfate-treated fractions from reference and field strains of Serpulina hyodysenteriae, Serpulina innocens, and Serpulina pilosicoli were characterized by Western blotting with a rabbit polyclonal antibody (PAb) specific for the 44-kDa PF sheath protein of S. hyodysenteriae (Z. Li, F. Dumas, D. Dubreuil, and M. Jacques, J. Bacteriol. 175:8000-8007, 1993) and a murine monoclonal antibody (MAb), designated 7G2, specific for the PF core FlaB proteins of S. hyodysenteriae. The MAb 7G2 reacted with a conserved epitope present in the 37-, 34-, and 32-kDa PF core FlaB proteins of all Serpulina species. This suggested that the core FlaB proteins are conserved among porcine Serpulina species. An immunoreactive band of approximately 44 kDa was present with all S. hyodysenteriae, S. innocens, and S. pilosicoli strains that were reacted with the PAb. The specificities of the PAb and the MAb for the FlaA1 and FlaB proteins of Serpulina species were confirmed by N-terminal amino acid sequencing of 44- and 37-kDa proteins, respectively, of S. hyodysenteriae and S. pilosicoli. Results from this study provide further evidence that the 44-kDa protein FlaA1 and the 37-, 34-, and 32-kDa FlaB proteins are conserved among porcine Serpulina species. 相似文献
10.
Linkage of hereditary haemorrhagic telangiectasia to chromosome 9q34 and evidence for locus heterogeneity. 总被引:11,自引:3,他引:11
下载免费PDF全文
![点击此处可从《Journal of medical genetics》网站下载免费的PDF全文](/ch/ext_images/free.gif)
P Heutink T Haitjema G J Breedveld B Janssen L A Sandkuijl C J Bontekoe C J Westerman B A Oostra 《Journal of medical genetics》1994,31(12):933-936
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder with unknown pathophysiology that is characterised by arteriovenous lesions and recurrent haemorrhage in virtually every organ. Linkage of HHT to markers on chromosome 9q has recently been reported. In this study we report confirmation of this localisation in three unrelated families of Dutch origin. A fourth unrelated HHT family, in which considerably fewer pulmonary arteriovenous malformations (PAVM) were present, yielded evidence for non-linkage to this region. We conclude that HHT is a genetically heterogeneous disorder and our results indicate that the presence of PAVM may be more common in patients with a chromosome 9 linked form of HHT than in patients with the non-linked form. 相似文献