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排序方式: 共有298条查询结果,搜索用时 15 毫秒
1.
S. TAJIMA K. SHIMIZU T. IZUMI S. KURIHARA T. HARADA† 《The British journal of dermatology》1995,133(2):303-305
We describe two patients with lesions clinically resembling pseudoxanthoma elasticum and histologically exhibiting focal elastosis. with normal-appearing elastic fibres in the mid- and deep dermis. We consider that these skin lesions represent a previously undescribed entity, whose pathogenesis appears to be related to the ageing process. 相似文献
2.
YASUMASA SHICHIRI NORIYASU TAKAO TOMOYUKI OIDA HIROSHI KANAMARU YOSUKE SHIMIZU 《International journal of urology》2004,11(11):1019-1023
The most serious problem regarding a laparoscopic partial nephrectomy is how to perform bloodless excision without causing renal ischemia in a limited working space. We report the case of a 65-year-old man with left small renal cell carcinoma in the posterior mid zone who underwent a laparoscopic partial nephrectomy through a retroperitoneal approach by carrying out the ligation of the tumor-feeding artery, but without clamping the renal pedicle. Both preoperative abdominal computed tomography (CT) and intraoperative ultrasonography revealed the tumor to be fully encapsulated. The tumor-feeding artery could be exposed by dissection from the renal hilum and, after an arterial ligation, tumor resection with a safety margin was smoothly performed with minimal bleeding. Postoperatively, CT revealed a limited defect of the renal parenchyma and excretory pyelography showed no urine leakage or urinary tract obstruction. The preoperative and postoperative creatinine levels were 0.66 and 0.69 mg/dL, respectively. As a result, a tumor-feeding artery ligation with a laparoscopic partial nephrectomy for left renal cell carcinoma in the posterior mid zone is considered to be an effective surgical modality which avoids renal ischemia and pelvic heat injury. 相似文献
3.
ATSUKO BABA KUNIHISA TANIGUCHI WATARU MOTOKAWA KAZUNARI ISHIBASHI ATSUHITO OKINA KIMIO ABE 《The Journal of pharmacy and pharmacology》1995,47(6):518-523
Fluid and protein secretion by the submandibular glands of 25-day-old rats were examined and compared in response to three cholinergic and four peptidergic sialogogues at various doses. All cholinergic and peptidergic agonists used were potent sialogogues for the submandibular glands of the weanling rats over the wide range of doses used. The cholinergic agonists, bethanechol and methacholine and the peptidergic agonists, substance P, substance PTyr8 and eledoisin-related peptide used intravenously, acted similarly to each other on the submandibular glands of the rats, late in the natural weaning period, but carbachol and physalaemin had slightly different effects. Of the peptidergic agonists, physalaemin was the most potent sialogogue among four tachykinins tested at the low dose. The types of protein secreted by the submandibular glands of the weanling rats in response to all sialogogues used here were typical of the β-type. These results indicate that all agonists used could mainly stimulate the acinar cells of the submandibular glands of the weanling rats which have already fully developed functionally at this time. 相似文献
4.
Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects 总被引:1,自引:0,他引:1
HIROSHI FUKUZAKO md TOMO HASHIGUCHI md YASUHIRO SAKAMOTO md HISATAKA OKAMURA md WATARU DOI md KAORU TAKENOUCHI md MORIKUNI TAKIGAWA md 《Psychiatry and clinical neurosciences》1997,51(4):261-263
Abstract To determine whether there are metabolite changes in the left medial temporal and frontal lobes with aging, we performed proton magnetic resonance spectroscopy in 36 normal subjects. The N-acetylaspartate/creatine-phosphocreatine ratio in the medial temporal lobe tended to be decreased in subjects over 60 years of age. The ratio decrease in the frontal lobe related to aging was lower than that in the medial temporal lobe. There were no significant differences in the metabolite ratios between males and females. These findings suggest that structures in the medial temporal lobe may be more susceptible to neuronal dysfunction associated with aging than those in the frontal lobe. 相似文献
5.
H. MlZUTANI S. OHYANAGI T. HAYASHI R. W. GROVES † K. SUZUKI M. SHIMIZU 《The British journal of dermatology》1996,135(2):187-193
Summary In normal human skin, immtmoreactive thrombomodulin (TM) is expressed in a strict differentiation related pattern. solely in suprabasal spinous layer keratinocytes. To evaluate the polential application of TM as a differentiation marker for keratinocyte-derived skin tumours, we have studied immunohistopathological, biochemical and functional TM activities in various skin tumours. Immunoreactive, full sized and enzymatically active TM was expressed in keratinocyte-derived skin tumours (squamous cell carcinoma, seborrhoeic keratosis and partly Bowen's disease), as well as normal epidermal keratinoeytes and endothelial cells. However, no TM was detected in basal cell carcinotnas, senile keratosis or non-squanious epithelial tumours such as malignant melanoma, naevus pigmentosus and Paget's disease. Interestingly, decreased expression was observed in verruca vulgaris. These findings suggested that differentiation-dependent TM expression was restricted to epithelial skin tumours and undetectable on neural crest derived tumours. TM is a differentiation marker for spinous layer keratinocytes and is a useful tool in histopathological study of epithelial tumours. 相似文献
6.
C. TASHIRO MD N. INAMORI MD H. TANIGAMI MD M. NISHIMURA MD K. FUKUMITSU MD I. SHIMIZU MD 《Paediatric anaesthesia》1993,3(1):41-45
Fetal anaesthesia was performed 5 times in 1 patient to treat pleural effusions, obtain fetal blood sampling, provide albumin infusion, and establish and replace a pleuro-amniotic indwelling shunt catheter under ultrasound guidance. A maternal epidural catheter was placed and used for epidural anaesthesia for the first 4 anaesthetics. Fetal administration of pancuronium 0.15 mg·kg?1 via the umbilical vein or 0.25 mg·kg?1 intramuscularly was enough to produce immobilization without maternal effect. However, maternal pretreatment with intravenous diazepam and fentanyl was required for fetal sedation and analgesia, which was necessary for accurate and safe injection, and for suppression of fetal stress. 相似文献
7.
Ken SAITO Hideo SHIMIZU Takeshi YOKOYAMA Katsuya KAWATA Takanori MATSUMURA Yasuhiko MORIOKA 《Pathology international》1983,33(2):249-256
Four cases of Ischemic enterocolitis without arterio–occlusive lesion were described. Three cases were associated with sigmoid colon carcinomas. Ischemic lesions developed anal to the carcinomas in two cases, and oral to sigmoidostomy to relieve intestinal obstruction by carcinoma in one case. One other case was associated with inguinal hernia. Grossly, ischemic lesions involved relatively short intestinal segments, and the ischemic colonic lesions were not related to teniae coli. Extensive veno–occlusive lesions were discovered in a case of ischemic stricture of the ileum, which had been incarcerated in the right inguinal hernia. Reversible mechanical occlusion of the intestinal vessels caused by transient or recurrent intestinal strangulation is the most probable cause of these ischemic lesions., ACTA PATHOL. JPN. 33: 249–256, 1983. 相似文献
8.
Takeshi SHIMIZU Shingo TOYOTA Kanji NAKAGAWA Tomoaki MURAKAMI Kanji MORI Haruhiko KISHIMA Takuyu TAKI 《Neurologia medico-chirurgica》2021,61(1):55
One of the merits of recently introduced exoscopes, including ORBEYE, is that they are superior to a conventional microscope in terms of ergonomic features. Taking advantage of it, the retrosigmoid approach can be performed in the supine position using ORBEYE. We report a consecutive series of 14 operations through the retrosigmoid approach in the supine position using ORBEYE. Fourteen consecutive patients who underwent surgery through the retrosigmoid approach for cerebellopontine (CP) angle lesions in the supine position using ORBEYE were targeted, and surgical outcomes and complications were examined. We evaluated the posture of the operator and the surgical field during this approach compared with those using a conventional microscope. In all 14 cases, all operative procedures were accomplished only using the ORBEYE. There were no operative complications due to this approach. Using ORBEYE, even when the angle of the operative visual axis was horizontal, the operators could manipulate in a comfortable posture. They were not forced to be in an uncomfortable posture that extended their arms, as is often the case with a conventional microscope. Therefore, they could use shorter surgical instruments. As the cerebellum shifted downward with gravity even using slight retraction during this approach, the working space of the surgical field was easily secured. Through this approach, the operators can perform stable microsurgery of CP angle lesions in a comfortable posture. This approach can reduce the burden on the operator and the patient, leading to a refined surgical procedure. 相似文献
9.
HISAKI MAKIMOTO M.D. Ph.D. IKUTARO NAKAJIMA M.D. KOJI MIYAMOTO M.D. YUKO YAMADA M.D. HIDEO OKAMURA M.D. TAKASHI NODA M.D. Ph.D. TAKESHI AIBA M.D. Ph.D. SHIRO KAMAKURA M.D. Ph.D. KENGO KUSANO M.D. Ph.D. WATARU SHIMIZU M.D. Ph.D. KAZUHIRO SATOMI M.D. Ph.D. 《Pacing and clinical electrophysiology : PACE》2015,38(5):630-640
10.
Jiro OHARA Motoaki FUJIMOTO Shoichi TANI Hideki OGATA Kampei SHIMIZU Tomoaki TAGUCHI Masahiko ITANI Yoshinori AKIYAMA 《Neurologia medico-chirurgica》2022,62(3):149
We describe three cases with acute middle cerebral artery (MCA) occlusion. From the pre-operative MRI, including three-dimensional turbo spin-echo sequences using T1WI and T2WI, we assessed both thrombus configuration and arterial anatomy at the MCA bifurcations. For efficient endovascular thrombectomy, we identified the applied MCA segment 2 (M2) branch, in which the main thrombus was buried. Sufficient recanalization after a single pass was achieved and the patients made a marked recovery. Although mechanical thrombectomy for M2 occlusion has not been of proven benefit, the endovascular procedure based on three-dimensional turbo spin-echo imaging is useful for more complete thrombus removal at MCA bifurcations. 相似文献