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Imaging the right heart pulmonary circulation unit: Insights from advanced ultrasound techniques
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Francesco Ferrara MD PhD Luna Gargani MD PhD Ellen Ostenfeld MD Michele D'Alto MD PhD Jaroslaw Kasprzak MD Damien Voilliot MD Christine Selton‐Suty MD Olga Vriz MD Alberto M. Marra MD Paola Argiento MD Anna A. Stanziola MD PhD Antonio Cittadini MD PhD Antonello D'Andrea MD PhD Eduardo Bossone MD PhD 《Echocardiography (Mount Kisco, N.Y.)》2017,34(8):1216-1231
The right heart pulmonary circulation unit (RH‐PCU) is a key determinant of prognosis in several cardiorespiratory diseases. Although right heart catheterization is considered the gold standard for pulmonary hemodynamic assessment, a comprehensive cardiovascular ultrasound approach is an essential step in the diagnostic–prognostic clinical pathway of patients with suspect or overt pulmonary hypertension. The exponential development of advanced ultrasound techniques (strain, 3‐dimensional echocardiography and lung ultrasound) has led to new insights into the evaluation of RH‐PCU structure and function, overcoming some limitations of standard Doppler echocardiography. In the near future, exercise Doppler echocardiography may become a useful technique for detecting a latent stage of pulmonary hypertension and for evaluating right ventricular contractile reserve. 相似文献
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Vriz Olga Palatini Paolo Mos Lucio AlSergani Hani Vendramin Igor Livi Ugolino Antonini-Canterin Francesco Magne Julien 《The international journal of cardiovascular imaging》2021,37(5):1659-1668
The International Journal of Cardiovascular Imaging - Aortic valve stenosis (AS) shares similarities with the atherosclerotic process but little is known about the effect of the mechanical... 相似文献
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Veldtman Gruschen Possner Mathias Mohty Dania Issa Ziyad Alsaleh Monerah AlMarzoog AlJuhara Thaar Emmanual Shisamma Salam Yezan AlHabdan Mohammed Saleh Alsaied Tarek Rathod Rahul H. Siblini Ghassan Vriz Olga 《The international journal of cardiovascular imaging》2021,37(9):2651-2660
The International Journal of Cardiovascular Imaging - Abnormal atrial mechanics in biventricular circulations have been associated with elevated left heart filling pressures. Similar associations... 相似文献
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Olga Vriz Julien Magne Caterina Driussi Gabriele Brosolo Francesco Ferrara Paolo Palatini Victor Aboyans Eduardo Bossone 《The international journal of cardiovascular imaging》2017,33(4):521-531
Arterial stiffness and compliance parameters from two adjacent elastic arteries [aorta and common carotid artery (CCA)] were compared and their relationship with left ventricular (LV) structure and function and clinical parameters was assessed. 584 healthy subjects were prospectively enrolled [mean age 47.8?±?18.4 years, range 16–94; 318 (54.4%) men]. They underwent comprehensive transthoracic echocardiography; M-mode diameters were measured at the level of the ascending aorta in systole and diastole and by echo-tracking at the level of the left CCA. The β-stiffness, pressure-strain elastic modulus, arterial compliance and one-point pulse wave velocity were derived. A significant correlation was observed between aortic and CCA stiffness and compliance parameters (p?<?0.0001 for all). At multiple regression analysis, CCA stiffness parameters were constantly correlated with age and systolic blood pressure, and accounted for up to 56% of the variability (vs. only 29% in aortic stiffness and compliance). CCA stiffness parameters were found to better predict LV structure, diastolic function than aortic stiffness parameters. Aortic and CCA stiffness and compliance were found to correlate with each other and with age, with the correlation being higher for CCA stiffness. At multiple regression analysis, CCA stiffness parameters were better predictors of LV structure and function than aortic stiffness. 相似文献
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Alberto M. Marra Nicola Benjamin Francesco Ferrara Olga Vriz Michele D’Alto Antonello D’Andrea Anna Agnese Stanziola Luna Gargani Antonio Cittadini Ekkehard Grünig Eduardo Bossone 《The international journal of cardiovascular imaging》2017,33(2):219-226
The right ventricular outflow tract acceleration time (RVOT-AT) has shown to progressively shorten with increasing degrees of pulmonary pressure. However, the physiologic ranges of RVOT AT are based on small sample sizes and have not been investigated regarding their determining factors. The aim of this study was to investigate reference values and determining factors of RVOT-AT in a large population of healthy subjects and by values described in the literature. In the first part of the study, 1029 healthy subjects (mean age 45.6?±?16.0 years, 565 (54.7?%) females) were prospectively assessed by clinical examination including demography, vital signs and echocardiography. In the second part, we performed a pooled analysis of eight published studies describing RVOT-AT in healthy subjects (n?=?450). Statistical analysis included the calculation of 5?% quantiles for defining reference values. RVOT-AT significantly but weakly correlated with age (r: ?0.207; p?<?0.001), body mass Index (r: ?0.16), systolic (r: ?0.158) and diastolic (r: ?0.137) blood pressure, heart rate (r: ?0.197) and left ventricular (LV) E/A ratio (r: 0.229) (all p?<?0.001). No differences were found with regards to sex. In a synopsis of both prospective and literature-based data sets, RVOT-AT weighted means was 138.51 ms and the 5?% quantile was 104.7 ms (95?% confidence interval 98.2–110.1). This study delineates the range of RVOT-AT in healthy adults and it’s determining factors. Our study is in line with the cut-off value stated by the European guidelines with an RVOT-AT ≤105 ms denoting abnormal values. 相似文献
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Palatini P Vriz O Nesbitt S Amerena J Majahalme S Valentini M Julius S 《Hypertension》1999,33(3):769-774
Controversy surrounds the pathogenetic mechanisms of the relationship between hyperdynamic circulation and insulin resistance. Two hundred eight children and young adults (mean age, 17.2+/-3.0 years; range, 11 to 26 years) from the Tecumseh Offspring Study whose parents had been assessed with Doppler echocardiography at the age of 34 years during the previous Tecumseh Blood Pressure Study were considered for this analysis. Offspring data were stratified according to tertiles of parental cardiac index. Parents in the top cardiac index tertile had increased heart rate (P=0.001), stroke volume (P=0.0001), left ventricular fractional shortening (P=0.02), and plasma epinephrine (P=0.02) compared with parents in the other tertiles. Body mass index (BMI) and blood pressure were similar in all groups. Offspring of parents with a high cardiac index had greater BMI (P=0.001), skinfold thickness (P=0.008), and waist/hip ratio (P=0.02), higher diastolic blood pressure (P=0.02) and plasma insulin level (P=0.001), and higher heart rate during Stroop's color test (P=0.02) than offspring of parents with a lower cardiac index. In a multivariate regression analysis, offspring BMI was predicted by parental BMI and cardiac index (P=0.0001 and 0.003, respectively). The mother-child relationship explained most of the cardiac index-BMI association. In summary, parental hyperdynamic circulation was an important predictor of overweight, abnormal fat distribution, increased blood pressure, and hyperinsulinemia in offspring. Our results illustrate the complexity of interaction between a genetic tendency and its phenotypic expression. We speculate that the degree of beta-adrenergic responsiveness may be a major determinant of the phenotypic differences between the parents and offspring found in this study. 相似文献
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Ticulescu CR Vriz O Sparacino L Popescu BA Ginghina C Nicolosi GL Cervesato E Panarello G Carerj S Antonini-Canterin F 《Angiology》2011,62(8):662-668
Cardiovascular remodeling in chronic kidney disease (CKD) is responsible for the high mortality found in this condition. A total of 89 consecutive outpatients with stage III CKD and 52 patients with stage II CKD with similar degree of traditional atherosclerotic risk factors underwent routine echocardiographic and carotid Doppler examination, evaluating vascular and cardiac remodeling (intima-media thickness [IMT] and left ventricular mass index [LVMi]), and its relation with arterial stiffness, determined in the same examination, using an echo-tracking technique. Also the absolute values of LVMi and IMT were statistically similar between the 2 groups, their determinants were completely different, only in stage III the markers of renal impairment and arterial stiffness being independent predictors of cardiac and vascular modifications. We concluded that macroanatomical measurements do not fully describe cardiovascular remodeling in this setting. Arterial stiffness echo-tracking derived could add valuable information, being an easy-to-perform parameter during a routine examination. 相似文献
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Different correlates but similar prognostic implications for right ventricular dysfunction in heart failure patients with reduced or preserved ejection fraction
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