全文获取类型
收费全文 | 1183篇 |
免费 | 29篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 32篇 |
妇产科学 | 12篇 |
基础医学 | 244篇 |
口腔科学 | 14篇 |
临床医学 | 136篇 |
内科学 | 156篇 |
皮肤病学 | 10篇 |
神经病学 | 37篇 |
特种医学 | 53篇 |
外科学 | 252篇 |
综合类 | 8篇 |
预防医学 | 59篇 |
眼科学 | 73篇 |
药学 | 45篇 |
中国医学 | 1篇 |
肿瘤学 | 59篇 |
出版年
2022年 | 18篇 |
2021年 | 13篇 |
2018年 | 10篇 |
2016年 | 11篇 |
2015年 | 9篇 |
2014年 | 9篇 |
2013年 | 22篇 |
2012年 | 18篇 |
2011年 | 21篇 |
2010年 | 32篇 |
2009年 | 18篇 |
2008年 | 34篇 |
2007年 | 38篇 |
2006年 | 28篇 |
2005年 | 24篇 |
2004年 | 17篇 |
2003年 | 23篇 |
2002年 | 26篇 |
2001年 | 25篇 |
2000年 | 19篇 |
1999年 | 23篇 |
1998年 | 11篇 |
1997年 | 13篇 |
1996年 | 11篇 |
1993年 | 9篇 |
1992年 | 30篇 |
1991年 | 29篇 |
1990年 | 42篇 |
1989年 | 46篇 |
1988年 | 44篇 |
1987年 | 52篇 |
1986年 | 34篇 |
1985年 | 54篇 |
1984年 | 25篇 |
1983年 | 19篇 |
1982年 | 9篇 |
1979年 | 23篇 |
1978年 | 21篇 |
1977年 | 17篇 |
1976年 | 22篇 |
1975年 | 26篇 |
1974年 | 15篇 |
1973年 | 32篇 |
1972年 | 18篇 |
1971年 | 25篇 |
1970年 | 19篇 |
1969年 | 21篇 |
1968年 | 15篇 |
1967年 | 21篇 |
1966年 | 20篇 |
排序方式: 共有1214条查询结果,搜索用时 31 毫秒
1.
2.
3.
4.
As many as 60 patients with combined pathologies (chronic hepatitis (CH) and chronic non-calculous cholecystitis (CNCC)) were examined, and 20 healthy subjects were included in the control group. The efficacy of Essliver Forte for patients with chronic non-calculous cholecystitis combined with chronic hepatitises (both viral hepatitis and steatohepatitis) was assessed on the basis of clinical, biochemical and bacteriological criteria. Essliver Forte was found to improve the clinical and biochemical parameters of the functional liver condition, bile biochemical characteristics and intestinal microbiocenosis in patients with combined pathologies. The positive clinical effect is most evident for patients with chronic non-calculous cholecystitis and chronic steatohepatitis (both alcohol and non-alcohol). Essliver Forte can be recommended for treatment of patients with combined pathologies. 相似文献
5.
6.
The modulation of drug metabolising enzymes by Masheri extract (ME) and Benzo(a)Pyrene [B(a)P] was studied in male Sprague Dawley rats fed different dietary protein levels. Two groups of 21 days old male Sprague Dawley rats were put on a high protein diet (SHP) with 20% Casein, and a low protein diet (SLP) with 3% Casein semisynthetic based diets for 12 weeks. The SLP fed animals showed lower basal levels of the Phase I activating enzymes viz. Cytochrome P450, Benzo(a)Pyrene hydroxylase, Benzphetamine demethylase and Phase II glutathione detoxification system viz. Glutathione (GSH) and Glutathione-S-transferase. ME and B(a)P treatment significantly depleted the glutathione detoxification system in the SLP group whereas an opposite effect was observed in the SHP group. Interstingly, ME and B(a)P treated rats in the SLP group showed a higher percent increase in the hepatic and pulmonary Phase I enzyme activities than those observed in the treated ME/B(a)P treated SHP rats. Furthermore, both ME and B(a)P significantly decreased the hepatic pool of vitamin A while a concomittant increase in that of vitamin C was observed. 相似文献
7.
8.
Classical and anaplastic seminoma: difference in survival 总被引:1,自引:0,他引:1
Classical and anaplastic seminoma are traditionally treated with radiation therapy and are said to have the same prognosis. A retrospective study was undertaken of 90 seminoma patients treated with radiation therapy between 1961 and 1985. The classical group consisted of 71 patients of whom 50 had stage I and 21 had stage II disease. The anaplastic group consisted of 19 patients of whom ten had stage I and nine had stage II disease. The median follow-up time was 64 months for the entire group. The 10-year relapse-free survival rate for the classical group was 94% and for the anaplastic group was 70% (P less than .05). For patients with classical stage I disease, the relapse-free actuarial survival rate was 98%; for patients with anaplastic stage I disease, it was 64% (P less than .02). For the classical stage II disease group, the relapse-free actuarial survival rate was 84% and for the anaplastic stage II disease group, 75% (P less than .70). Four patients in the classical group (6%) had relapses; of these, one patient had local recurrence of tumor, and three had distant metastases. In the anaplastic group, four patients (21%) had relapses; two patients had local recurrence of tumor, and two had distant metastases. Therefore the data suggest a difference in survival and relapse rates between classical and anaplastic seminoma. 相似文献
9.
目的:应用酵母双杂交方法筛选BRCA2相互作用蛋白编码基因,验证其相互作用并研究其功能联系。方法:以BRCA2基因3′端片段构建酵母双杂交质粒,筛选正常人乳腺上皮细胞cDNA库,获得编码相互作用蛋白的基因,采用免疫共沉淀、哺乳细胞双杂交和荧光酶测定等方法进一步验证蛋白间相互作用和功能联系.结果:采用酵母双杂交系统筛选,获得了多个编码BRCA2相互作用蛋白的基因,其中包括已知的FHL2蛋白;免疫共沉淀和哺乳动物细胞双杂交试验显示BRCA2和FHL2在体内特异性结合,并证实FHL2在体内形成同源二聚体;转录活性分析发现BRCA2与FHL2有协同转录激活作用。结论:发现BRCA2与FHL2蛋白间相互作用和功能联系,为BRCA2功能研究提供了新的方向。 相似文献