UVB靶向光疗治疗斑块型银屑病

目的:确定UVB靶向光疗治疗局限性银屑病是否安全有效及是否存在量效关系。设计:随机、对评估者设盲对照研究。机构:泰国曼谷大学医院皮肤病门诊。患者:14例稳定性局限性斑块型银屑病患者。干预:依据预定的最小红斑量(M EDs),随机给予患者不同通量的UVB靶向光线治疗,3次/周。在4     

Ultrafast-charging and long cycle-life anode materials of TiO2-bronze/nitrogen-doped graphene nanocomposites for high-performance lithium-ion batteries

Emerging technologies demand a new generation of lithium-ion batteries that are high in power density, fast-charging, safe to use, and have long cycle lives. This work reports charging rates and specific capacities of TiO₂(B)/N-doped graphene (TNG) composites. The TNG composites were prepared by the hydrothermal method in various reaction times (3, 6, 9, 12, and 24 h), while the N-doped graphene was synthesized using the modified Hummer''s method followed by a heat-treatment process. The different morphologies of TiO₂ dispersed on the N-doped graphene sheet were confirmed as anatase-nanoparticles (3, 6 h), TiO₂(B)-nanotubes (9 h), and TiO₂(B)-nanorods (12, 24 h) by XRD, TEM, and EELS. In electrochemical studies, the best battery performance was obtained with the nanorods TiO₂(B)/N-doped graphene (TNG-24h) electrode, with a relatively high specific capacity of 500 mA h g⁻¹ at 1C (539.5 mA g⁻¹). In long-term cycling, excellent stability was observed. The capacity retention of 150 mA h g⁻¹ was observed after 7000 cycles, at an ultrahigh current of 50C (27.0 A g⁻¹). The synthesized composites have the potential for fast-charging and have high stability, showing potential as an anode material in advanced power batteries for next-generation applications.

The TiO₂-bronze/nitrogen-doped graphene nanocomposites have the potential for fast-charging and have high stability, showing potential as an anode material in advanced power batteries for next-generation applications.     

Schools for health, education and development: a call for action

In 2007, the World Health Organization, together with UnitedNations and international organization as well as experts, metto draw upon existing evidence and practical experience fromregions, countries and individual schools in promoting healththrough schools. The goal of the meeting was to identify currentand emerging global factors affecting schools, and to help themrespond more effectively to health, education and developmentopportunities. At the meeting, a Statement was developed describingeffective approaches and strategies that can be adopted by schoolsto promote health, education and development. Five key challengeswere identified. These described the need to continue buildingevidence and capturing practical experience in school health;the importance of improving implementation processes to ensureoptimal transfer of evidence into practice; the need to alleviatingsocial and economic disadvantage in access to and successfulcompletion of school education; the opportunity to harness mediainfluences for positive benefit, and the continuing challengeto improve partnerships among different sectors and organizations.The participants also identified a range of actions needed torespond to these challenges, highlighting the need for actionby local school communities, governments and international organizationsto invest in quality education, and to increase participationof children and young people in school education. This paperdescribes the rationale for and process of the meeting and thedevelopment of the Statement and outlines some of the most immediateefforts made to implement the actions identified in the Statement.It also suggests further joint actions required for the implementationof the Statement.     

Rice husk-derived nano-SiO2 assembled on reduced graphene oxide distributed on conductive flexible polyaniline frameworks towards high-performance lithium-ion batteries

By combining rice husk-derived nano-silica and reduced graphene oxide and then polymerizing PANI by in situ polymerization, we created polyaniline-coated rice husk-derived nano-silica@reduced graphene oxide (PANI-SiO₂@rGO) composites with excellent electrochemical performance. ATR-FTIR and XRD analyses confirm the formation of PANI-SiO₂@rGO, implying that SiO₂@rGO served as a template in the formation of composites. The morphology of PANI-SiO₂@rGO was characterized by SEM, HRTEM, and STEM, in which SiO₂ nanoparticles were homogeneously loaded on graphene sheets and the PANI fibrous network uniformly covers the SiO₂@rGO composites. The structure can withstand the large volume change as well as retain electronic conductivity during Li-ion insertion/extraction. Over 400 cycles, the assembled composite retains a high reversible specific capacity of 680 mA h g⁻¹ at a current density of 0.4 A g⁻¹, whereas the SiO₂@rGO retains only 414 mA h g⁻¹ at 0.4 A g⁻¹ after 215 cycles. The enhanced electrochemical performance of PANI-SiO₂@rGO was a result of the dual protection provided by the PANI flexible layer and graphene sheets. PANI-SiO₂@rGO composites may pave the way for the development of advanced anode materials for high-performance lithium-ion batteries.

By combining rice husk-derived nano-silica and reduced graphene oxide and then polymerizing PANI by in situ polymerization, we created polyaniline-coated rice husk-derived nano-silica@reduced graphene oxide composites with excellent electrochemical performance.     

Targeted UV-B phototherapy for plaque-type psoriasis

OBJECTIVE: To determine whether targeted UV-B phototherapy is efficacious and safe in the treatment of localized psoriasis and whether there is a dose-response relationship. DESIGN: Randomized, evaluator-blind, controlled study. SETTING: Dermatology clinic in a large university-based hospital in Bangkok, Thailand. PATIENTS: Fourteen patients with stable, localized, plaque-type psoriasis. INTERVENTIONS: Patients were randomized to receive different fluences of targeted UV-B phototherapy 3 times weekly based on predetermined minimal erythema doses (MEDs). Treatment fluences were constant throughout the study period of 4 weeks. Follow-up was carried out until lesions returned to original state. MAIN OUTCOME MEASURES: Modified psoriasis area and severity index. RESULTS: All fluences of UV-B produced some clinical improvement and were very well tolerated. Fluences ranging from 1 to 6 multiples of MEDs resulted in clearance of lesions in some patients with 6 MEDs producing clearance in 77% of patients. The number of treatments required to clear psoriatic lesions when 2 to 6 MEDs were used was 5.0 to 6.1 treatments. The only adverse events observed were erythema, which was asymptomatic in most subjects, and hyperpigmentation. CONCLUSIONS: Incoherent, targeted UV-B phototherapy is a safe and efficacious treatment modality for localized psoriasis. Its value in other UV-B responsive conditions should be further investigated.