全文获取类型
收费全文 | 16497篇 |
免费 | 1179篇 |
国内免费 | 45篇 |
专业分类
耳鼻咽喉 | 161篇 |
儿科学 | 562篇 |
妇产科学 | 226篇 |
基础医学 | 1811篇 |
口腔科学 | 384篇 |
临床医学 | 1634篇 |
内科学 | 3997篇 |
皮肤病学 | 477篇 |
神经病学 | 1668篇 |
特种医学 | 545篇 |
外科学 | 2230篇 |
综合类 | 227篇 |
现状与发展 | 1篇 |
一般理论 | 16篇 |
预防医学 | 1431篇 |
眼科学 | 326篇 |
药学 | 905篇 |
中国医学 | 13篇 |
肿瘤学 | 1107篇 |
出版年
2021年 | 246篇 |
2020年 | 137篇 |
2019年 | 249篇 |
2018年 | 291篇 |
2017年 | 185篇 |
2016年 | 219篇 |
2015年 | 263篇 |
2014年 | 380篇 |
2013年 | 607篇 |
2012年 | 858篇 |
2011年 | 885篇 |
2010年 | 510篇 |
2009年 | 499篇 |
2008年 | 893篇 |
2007年 | 925篇 |
2006年 | 882篇 |
2005年 | 878篇 |
2004年 | 834篇 |
2003年 | 787篇 |
2002年 | 747篇 |
2001年 | 328篇 |
2000年 | 348篇 |
1999年 | 331篇 |
1998年 | 175篇 |
1997年 | 165篇 |
1996年 | 151篇 |
1995年 | 142篇 |
1994年 | 135篇 |
1993年 | 125篇 |
1992年 | 234篇 |
1991年 | 211篇 |
1990年 | 190篇 |
1989年 | 222篇 |
1988年 | 195篇 |
1987年 | 205篇 |
1986年 | 217篇 |
1985年 | 204篇 |
1984年 | 194篇 |
1983年 | 178篇 |
1982年 | 162篇 |
1981年 | 155篇 |
1980年 | 128篇 |
1979年 | 167篇 |
1978年 | 134篇 |
1977年 | 127篇 |
1976年 | 128篇 |
1975年 | 128篇 |
1974年 | 121篇 |
1973年 | 117篇 |
1971年 | 100篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
ObjectivesTo fill an empirical gap in the literature by examining changes in quality of care measures occurring when multispecialty clinic systems were acquired by hospital-owned, vertically integrated health care delivery systems in the Twin Cities area.ConclusionsMoving a clinic system into a vertically integrated delivery system resulted in limited increases in quality of care indicators. Caution is warranted when the acquisition causes disruption in referral patterns. 相似文献
2.
3.
4.
5.
6.
Neurological dysfunction of the bladder in workers exposed to dimethylaminopropionitrile 总被引:1,自引:0,他引:1
Neurogenic bladder dysfunction, characterized by hesitancy, need to strain, decreased stream, and increased duration of urination, developed in 104 (63%) of 166 employees working in the manufacture of polyurethane foam. Highest rates of illness (69%) occurred in production workers, and no illness occurred in office or warehouse workers. Onset of the epidemic coincided with introduction of a catalyst, dimethylaminopropionitrile (DMAPN), and monthly case incidence rates increased as DMAPN use increased. Outbreak ceased abruptly when DMAPN use was stopped. Of eight patients who underwent neurourologic testing during recovery, seven lacked either detrusor reflex or normal sensation of bladder filling; seven had a subclinical sensory abnormality; three had prolonged sacral-evoked responses; and two of these three had limb motor neuropathies. Dimethylaminopropionitrile is unique among known neurotoxins in producing urinary symptoms more frequently than limb nerve symptoms. 相似文献
7.
8.
Chakraborty Bhaswat S. Sardessai Manik S. Jaworski Theodore J. Midha Kamal K. Hawes Edward M. 《Pharmaceutical research》1987,4(3):207-213
For the separate development of radioimmunoassay procedures for thioridazine and its two major active metabolites, mesoridazine and sulforidazine, three haptens, respectively, 2-methylthio-, 2-methylsulfinyl-, and 2-methylsulfonyl-substituted 10-[2-[l-(2-carboxyethyl)-2-piperidinyl]ethyl]-10H-phenothiazine, were synthesized and characterized. Thioridazine hapten was coupled to bovine serum albumin, whereas the haptens for mesoridazine and sulforidazine were coupled to porcine thyroglobulin. The number of hapten residues per mole of carrier protein was determined in each case by an ultraviolet spectrophotometric method. Polyclonal antibodies to each hapten–protein conjugate were obtained in rabbits, and titers of the antisera were checked by evaluating their binding characteristics to the appropriate tritiated analyte. A hapten for the ring sulfoxide metabolite of thioridazine was also synthesized. 相似文献
9.
Theodore Berk MD Robert F. Crochelt BA Dr. Steven R. Peikin MD 《Digestive diseases and sciences》1986,31(5):502-505
Obese Zucker rats are less responsive than their lean littermates to the effects of cholecystokinin-octapeptide on satiety and pancreatic growth and exocrine function. We hypothesized that the hyperphagia observed in obese Zucker rats may be caused by a decreased pyloric contractile response to cholecystokinin, resulting in an increased rate of gastric emptying, decreased postprandial gastric distention, and thus decreased satiety. Pyloric muscle strips from six obese Zucker rats and six lean littermates were mounted in separate tissue baths and isometric contraction was measured in response to acetylcholine and cholecystokinin-octapeptide. The dose-response curves for acetylcholine-and cholecystokinin-octapeptide-stimulated pyloric muscle contraction were similar for both the obese and the lean rats. (For cholecystokinin, D50 obese=4.0±0.6 nM, D50 lean=3.4±0.2 nM;P=0.16). We conclude that the decreased satiety response to cholecystokinin-octapeptide observed in obese Zucker rats is not secondary to a decreased pyloric responsiveness to cholecystokinin.This work was supported by NIH grant AM28303-03. 相似文献
10.
Penny H Feldman Christopher M Murtaugh Liliana E Pezzin Margaret V McDonald Timothy R Peng 《Health services research》2005,40(3):865-886
OBJECTIVE: To assess the impact and cost-effectiveness of two information-based provider reminder interventions designed to improve self-care management and outcomes of heart failure (HF) patients. DATA SOURCES/STUDY SETTING: Interview and agency administrative data on 628 home care patients with a primary diagnosis of HF. STUDY DESIGN: Patients were treated by nurses randomly assigned to usual care or one of two intervention groups. The basic intervention was an e-mail to the patient's nurse highlighting six HF-specific clinical recommendations. The augmented intervention supplemented the initial nurse reminder with additional clinician and patient resources. DATA COLLECTION: Patient interviews were conducted 45 days post admission to measure self-management behaviors, HF-specific outcomes (Kansas City Cardiomyopathy Questionnaire-KCCQ), health-related quality of life (EuroQoL), and service use. PRINCIPAL FINDINGS: Both interventions improved the mean KCCQ summary score (15.3 and 12.9 percent, respectively) relative to usual care (p< or =.05). The basic intervention also yielded a higher EuroQoL score relative to usual care (p< or =.05). In addition, the interventions had a positive impact on medication knowledge, diet, and weight monitoring. The basic intervention was more cost-effective than the augmented intervention in improving clinical outcomes. CONCLUSIONS: This study demonstrates the positive impact of targeting evidence-based computer reminders to home health nurses to improve patient self-care behaviors, knowledge, and clinical outcomes. It also advances the field's limited understanding of the cost-effectiveness of selected strategies for translating research into practice. 相似文献