全文获取类型
收费全文 | 1501篇 |
免费 | 108篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 54篇 |
妇产科学 | 2篇 |
基础医学 | 97篇 |
口腔科学 | 22篇 |
临床医学 | 132篇 |
内科学 | 704篇 |
皮肤病学 | 10篇 |
神经病学 | 68篇 |
特种医学 | 56篇 |
外科学 | 54篇 |
综合类 | 39篇 |
一般理论 | 1篇 |
预防医学 | 69篇 |
眼科学 | 65篇 |
药学 | 185篇 |
肿瘤学 | 61篇 |
出版年
2022年 | 9篇 |
2021年 | 24篇 |
2020年 | 7篇 |
2019年 | 19篇 |
2018年 | 24篇 |
2017年 | 24篇 |
2016年 | 20篇 |
2015年 | 28篇 |
2014年 | 44篇 |
2013年 | 51篇 |
2012年 | 44篇 |
2011年 | 62篇 |
2010年 | 38篇 |
2009年 | 39篇 |
2008年 | 88篇 |
2007年 | 56篇 |
2006年 | 63篇 |
2005年 | 64篇 |
2004年 | 66篇 |
2003年 | 60篇 |
2002年 | 53篇 |
2001年 | 63篇 |
2000年 | 53篇 |
1999年 | 48篇 |
1998年 | 46篇 |
1997年 | 47篇 |
1996年 | 44篇 |
1995年 | 43篇 |
1994年 | 49篇 |
1993年 | 22篇 |
1992年 | 38篇 |
1991年 | 31篇 |
1990年 | 25篇 |
1989年 | 25篇 |
1988年 | 22篇 |
1987年 | 13篇 |
1986年 | 18篇 |
1985年 | 10篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1982年 | 7篇 |
1980年 | 8篇 |
1978年 | 7篇 |
1976年 | 10篇 |
1974年 | 6篇 |
1973年 | 17篇 |
1972年 | 8篇 |
1971年 | 9篇 |
1970年 | 6篇 |
1969年 | 7篇 |
排序方式: 共有1620条查询结果,搜索用时 0 毫秒
1.
2.
3.
4.
Benign intracranial hypertension and recombinant growth hormone therapy in Australia and New Zealand
PA Crock JD McKenzie AM Nicoll NJ Howard W Cutfield LK Shield G Byrne 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(4):381-386
Benign intracranial hypertension (BIH) is reported in three children from Australia and one from New Zealand, who were being treated with recombinant human growth hormone (rhGH). Three males and one female, aged between 10.5 and 14.2 y, developed intracranial hypertension within 2 weeks to 3 months of starting treatment. A national database, OZGROW, has been prospectively collecting data on all 3332 children treated with rhGH in Australia and New Zealand from January 1986 to 1996. The incidence of BIH in children treated with growth hormone (GH) is small, 1.2 per 1000 cases overall, but appears to be greater with biochemical GHD (<10IUml -1 ), i.e. 6.5/1000 (3 in 465 cases), relative risk 18.4, 95% confidence interval 1.9-176.1, than in all other children on the database. The incidence in patients with Turner's syndrome was 2.3/1000 (1 in 428 cases). No cases in patients with partial GHD (10–20 IUml -1 ) or chronic renal failure were identified. Possible causative mechanisms are discussed. The authors'practice is now to start GH replacement at less than the usual recommended dose of 14IUm-2 week-1 in those children considered to be at high risk of developing BIH. Ophthalmological evaluation is recommended for children before and during the first few months following commencement of rhGH therapy and is mandatory in the event of peripheral or facial oedema, persistent headaches, vomiting or visual symptoms. The absence of papilledema does not exclude the diagnosis. 相似文献
5.
6.
Noel R. Fajardo Filippo Cremonini Dr Nicholas J. Talley 《American Journal of Cancer》2006,5(5):319-330
In patients with cancer, constipation is a common complication. However, unlike in the general population, the impact of the symptoms of constipation on the quality of life in cancer patients is often greater. More importantly, in patients who are in the more advanced stages of the disease, constipation may also be suggestive of disease progression. Constipation as a symptom in this population is of significant importance as it may lead to life-threatening complications, i.e. bowel perforation due to fecal impaction. Therefore, in this regard, this problem deserves particular attention, as early recognition and management of complications may prevent further physical deterioration. This review aims to provide an overview of the management of constipation in patients with cancer. A symptom-based criteria definition for chronic constipation and prevalence of the problem in cancer patients provides a brief introduction. For the initial assessment and evaluation of constipation in cancer patients, an algorithm is described. The different possible etiologies of constipation in cancer patients are also discussed. Regarding therapeutic management, guidelines and recommendations for the use of different types of laxatives, stool softeners, suppositories and rectal enemas, prokinetic agents, antidepressant medications, and miscellaneous agents are succinctly discussed. Management of fecal impaction and opioid-induced bowel dysfunction are also described. Lastly, a brief overview of the management of acute colonic pseudo-obstruction and surgical or endoscopic options for large bowel obstruction are described. 相似文献
7.
8.
A worldwide survey of active duty military optometrists (Air Force, Army and Navy) was conducted in the spring of 1987. The survey response rate was 79%. Statistically significant differences (alpha = 0.01) in their roles, activities and attitudes are presented and discussed. Significant interservice differences were found in: types of duties, profession/status of immediate supervisors, work assignments, frequency and types of patient encounters, awareness of therapeutic drug policies, access to specific clinical instruments, and frequency of routine clinical tests. Attitude and opinion tabulations suggest an overall satisfaction with professional experiences and interprofessional working relationships. However, there was a common perception that optometrists did not receive appropriate promotional consideration or career opportunities within this multidisciplinary setting. Implications of survey results for non-military multidisciplinary health care institutions are also discussed. 相似文献
9.
10.
McGregor DH Yang Q Fan F Talley RL Topalovski M 《Annals of clinical and laboratory science》2001,31(1):103-107
Scabies, infection with Sarcoptes scabiei, is known to be predisposed to by poor body hygiene, environmental exposure, and systemic immunodeficiency. We report the case of an 83-year-old man with Sezary's syndrome who developed scabies limited to the skin of the upper chest, the same location where he had previously received electron beam radiation treatments for cutaneous T-cell lymphoma. Histologic and immunohistochemical studies demonstrated that sections of the previously irradiated right and left chest skin, compared to non-irradiated chest, abdominal, and leg skin, had infestation by scabies, diminished involvement by T-cell lymphoma, and notably reduced numbers of Langerhans cells. These findings suggest that the development of scabies may be predisposed to by local cutaneous radiation therapy, and that it may be mediated by local cutaneous immunodeficiency secondary to reduced numbers of Langerhans cells. 相似文献