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The present study evaluates the haemato-biochemical responses associated with fipronil exposure [(±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-trifluoromethylsulfinyl-pyrazole-3-carbonitrile] in Cyprinus carpio fry. Fish were exposed to sublethal concentration (1/3rd of LC50) (0.142 mg L?1) for 15 days and corresponding changes in different haemato-biochemical parameters were recorded at the end of experimental period. Significant (P < 0.05) increase in white blood cell counts, blood glucose, serum complement reactive protein and serum cortisol level were noticed, whereas haemoglobin and serum total protein contents were significantly (P < 0.05) decreased. Aspartate amino transferase, catalase and super oxide dismutase activities were significantly (P < 0.05) increased while alkaline phosphatase and malate dehydrogenase activities were significantly (P < 0.05) decreased. Similarly, 47 % inhibition in acetylcholine esterase activity was noticed due to fipronil stress. Results indicated that sublethal exposure of fipronil can induce haemato-biochemical alterations causing stress to C. carpio fry. Thus, haemato-biochemical parameters can be used as biomarkers for the sublethal toxicity of fipronil in the water bodies.  相似文献   
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Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - A 60&nbsp;days feeding trial was conducted to study the effects of dietary supplementation of...  相似文献   
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