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S. K. Gupta A. K. Pal N. P. Sahu N. Saharan Chandra Prakash M. S. Akhtar Sikendra Kumar 《Proceedings of the National Academy of Sciences, India. Section B.》2014,84(1):113-122
The present study evaluates the haemato-biochemical responses associated with fipronil exposure [(±)-5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-trifluoromethylsulfinyl-pyrazole-3-carbonitrile] in Cyprinus carpio fry. Fish were exposed to sublethal concentration (1/3rd of LC50) (0.142 mg L?1) for 15 days and corresponding changes in different haemato-biochemical parameters were recorded at the end of experimental period. Significant (P < 0.05) increase in white blood cell counts, blood glucose, serum complement reactive protein and serum cortisol level were noticed, whereas haemoglobin and serum total protein contents were significantly (P < 0.05) decreased. Aspartate amino transferase, catalase and super oxide dismutase activities were significantly (P < 0.05) increased while alkaline phosphatase and malate dehydrogenase activities were significantly (P < 0.05) decreased. Similarly, 47 % inhibition in acetylcholine esterase activity was noticed due to fipronil stress. Results indicated that sublethal exposure of fipronil can induce haemato-biochemical alterations causing stress to C. carpio fry. Thus, haemato-biochemical parameters can be used as biomarkers for the sublethal toxicity of fipronil in the water bodies. 相似文献
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Kumar Sikendra Prakash Chandra Gupta S. K. Chadha N. K. Jain K. K. Ghughuskar M. M. Pandey P. K. 《Proceedings of the National Academy of Sciences, India. Section B.》2017,87(1):243-252
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - A 60 days feeding trial was conducted to study the effects of dietary supplementation of... 相似文献
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