全文获取类型
收费全文 | 2574篇 |
免费 | 183篇 |
国内免费 | 66篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 43篇 |
妇产科学 | 12篇 |
基础医学 | 312篇 |
口腔科学 | 116篇 |
临床医学 | 204篇 |
内科学 | 667篇 |
皮肤病学 | 16篇 |
神经病学 | 111篇 |
特种医学 | 217篇 |
外科学 | 258篇 |
综合类 | 53篇 |
预防医学 | 124篇 |
眼科学 | 27篇 |
药学 | 328篇 |
中国医学 | 6篇 |
肿瘤学 | 321篇 |
出版年
2023年 | 15篇 |
2022年 | 23篇 |
2021年 | 54篇 |
2020年 | 31篇 |
2019年 | 48篇 |
2018年 | 49篇 |
2017年 | 56篇 |
2016年 | 59篇 |
2015年 | 55篇 |
2014年 | 66篇 |
2013年 | 83篇 |
2012年 | 106篇 |
2011年 | 126篇 |
2010年 | 65篇 |
2009年 | 51篇 |
2008年 | 96篇 |
2007年 | 134篇 |
2006年 | 81篇 |
2005年 | 91篇 |
2004年 | 90篇 |
2003年 | 72篇 |
2002年 | 81篇 |
2001年 | 98篇 |
2000年 | 82篇 |
1999年 | 92篇 |
1998年 | 56篇 |
1997年 | 69篇 |
1996年 | 27篇 |
1995年 | 36篇 |
1994年 | 29篇 |
1993年 | 28篇 |
1992年 | 70篇 |
1991年 | 74篇 |
1990年 | 63篇 |
1989年 | 60篇 |
1988年 | 54篇 |
1987年 | 47篇 |
1986年 | 65篇 |
1985年 | 69篇 |
1984年 | 40篇 |
1983年 | 26篇 |
1982年 | 20篇 |
1981年 | 15篇 |
1979年 | 22篇 |
1978年 | 12篇 |
1977年 | 20篇 |
1976年 | 17篇 |
1974年 | 14篇 |
1973年 | 11篇 |
1968年 | 14篇 |
排序方式: 共有2823条查询结果,搜索用时 15 毫秒
1.
2.
3.
Oswens Siu Hung Lo Wai Lun Law Hok Kwok Choi Yee Man Lee Judy Wai Chu Ho Chi Leung Seto 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(2):173-178
OBJECTIVES: The study aimed to review the etiologies of patients who underwent surgery for small bowel obstruction (SBO) and to evaluate the risk factors affecting the early postoperative outcomes. MATERIALS AND METHODS: A case series of 430 patients (252 men) with a mean age of 64.5 years, who underwent 437 operations for SBO, were retrospectively reviewed. RESULTS: Peritoneal adhesions and hernia were the most common causes of SBO, contributing 42.3 and 26.8% of all cases, respectively. Strangulation occurred in 27.7% and caused nonviable bowel in 13.0% of obstructing episodes. Old age (age >/= 70 years), female patient, nonadhesive obstruction, and hernia were the independent significant factors associated with bowel strangulation. The 30-day mortality was 6.5%, and the median postoperative hospital stay was 8 days. Old age, the presence of premorbid pulmonary disease, and malignant obstruction were the independent factors associated with operative mortality. The overall complication rate was 35.5%, and old age was the only significant factor associated with postoperative complications. CONCLUSIONS: Surgery for SBO is still associated with significant mortality and morbidity. As old age is significantly associated with an increased incidence of strangulation, operative mortality, and complications, this group of patients should be managed with extra cautions to avoid unfavorable outcome of surgery. 相似文献
4.
T Nishiyama A Hirasaki Y Odaka K Seto I Goto 《Masui. The Japanese journal of anesthesiology》1990,39(2):230-236
We compared midazolam 0.2 mg.kg-1 and fentanyl 50 micrograms with thiamylal 4 mg.kg-1 for rapid sequence induction. We could use midazolam safely in patients with bronchial asthma or drug allergy. There was no difference in time from the beginning of induction to intubation between midazolam treated group and thiamylal treated group. Changes in systolic as well as diastolic blood pressure and heart rate during 2 hours from intubation were smaller in midazolam treated group than in thiamylal treated group. In midazolam treated group, no arrhythmias were observed at the time of intubation. We could reduce the amount of anesthetics in midazolam treated group during 2 hours from intubation. From the results mentioned above, we conclude that midazolam is a useful agent for rapid sequence induction. 相似文献
5.
The effect of dietary manipulation on global tooth uptake of 47Ca-chloride was evaluated in three rat models of metabolic bone diseases verified by histologic bone study. The 24-hr tooth uptake of 47Ca-chloride was significantly decreased in the osteomalacic group, and was increased in the osteoporotic group at the fourth week. Tooth uptake closely paralleled femoral uptake at a correlation coefficient of 0.73 (p less than 0.01). The uptake of 47Ca-chloride in tooth was found to be more affected by dietary manipulation than that in femur in our rat models. 相似文献
6.
This is the second reported case of a malignant fibrous histiocytoma of the heart that metastasized to the brain. A 33-year-old woman developed headache, nausea, and ataxic gait 9 months after removal of the tumor from the left atrium of the heart. Computed tomographic and magnetic resonance imaging scans disclosed multiple metastatic tumors in the brain. Although dramatic improvement in her symptoms and signs followed the removal of the brain tumors, she died of tumor recurrence in the left atrium 3 months after the removal of the metastatic brain tumors. 相似文献
7.
8.
Yasuhiro Sano Shigeharu Yamashiro Asuka Komano Hisashi Maruko Hiroshi Sekiguchi Yasuo Takayama Ryoji Sekioka Kouichiro Tsuge Isaac Ohsawa Mieko Kanamori-Kataoka Yasuo Seto Akiyoshi Satoh 《Forensic Toxicology》2007,25(2):76-79
We previously reported that the Guardian Bio-Threat Alert (BTA) system could detect (detection limit: about 0.1 μg/ml) staphylococcal
enterotoxin B (SEB), botulinum toxins (BTX) A and B, and ricin, with no interference by white-powdered materials or colored
matrices. In this study, the capability of the BTA system was further assessed. With 10 min of preheating at 60°C, all toxins
could be detected, but with preheating at 80°C, BTX A and B and ricin became undetectable. About 20% SEB could be detected
after heating at 80°C, but this detection ability was completely removed after heating at 100°C. The effects of chemicals
usually used for decontamination, such as sodium hypochlorite, hydrogen peroxide, formaldehyde, and sodium nitrite, on the
detectability of SEB, BTX A, or ricin in the BTA system were also tested. The concentrations giving 50% line intensity for
SEB, BTX A, and ricin were 3.1, 11, and 15 μM for sodium hypochlorite and 88, 210, and 60 mM for formaldehyde, respectively.
The addition of hydrogen peroxide or sodium nitrite did not decrease the detectability even when used at high concentrations. 相似文献
9.
Akira Seto Shigehiro Morikawa Takahiro Isono Katsuhiko Ogawa Toshiro Inubushi 《Journal of medical virology》1995,46(3):224-229
Inbred rabbits of B/Jas strain were found to be highly susceptible to herpes simplex virus type 1 encephalitis, following i.v. injection of the virus, while Chbb:HM strain rabbits were not susceptible. The susceptibility trait seemed to be inherited recessively, involving multiple genes, because (B/Jas x Chbb:HM)Fl hybrids were as resistant as Chbb:HM rabbits, and because more than 90% of backcrosses of (B/Jas x Chbb: HM)FI to B/Jas were resistant to viral inoculation. The encephalitis in B/Jas rabbits resembled human herpes simplex encephalitis, in that the temporal lobe as well as the brain stem were affected preferentially, leading to the development of various types of seizures, such as circling, loss of balance leading to a fall, and tonic and clonic convulsions. The disease could be diagnosed by magnetic resonance imaging (MRI) analysis before onset of seizures, and diseased rabbits showed a marked lymphopenia at onset of seizures. © 1995 Wiley-Liss, Inc. 相似文献
10.
C Shimomura K Eguchi A Kurata M Seto G Mameya S Nagataki 《Ryūmachi》1991,31(5):519-27; discussion 525-6
We recently saw a patient who had aortitis syndrome associated with secondary amyloidosis. To our knowledge, she is the fourth report of this complication occurring in aortitis syndrome. In November 1985, the patient, a 18 year-old woman, was admitted to our hospital because of a high fever, back pain, abdominal pain and general fatigue. On physical examination, bruit was audible on the abdomen, bilateral radial artery was weakly palpable. Angiography showed the stenosis of bilateral carotid artery, subclavian artery, renal artery and superior mesenteric artery. From the above findings, she was diagnosed aortitis syndrome, and treatment was begun with prednisolone. However, she developed recurrently a high fever, chest pain, abdominal pain and exertional dyspnea. Laboratory findings at the active stage revealed the marked elevation of leukocytes, erythrocyte sedimentation rate and C-reactive protein. On her clinical course, the number of circulating thrombocytes was paralleled with the activity of the disease. On June 1988, she developed suddenly a high fever and severe pain of abdomen. Pathological findings of her stomach showed the deposition of amyloid protein A. Laboratory findings depicted the marked increment of thrombocytes, beta-thromboglobulin and platelet factor 4. These results suggest that circulating thrombocytes may play a role in product ion of amyloid protein. 相似文献