全文获取类型
收费全文 | 3410篇 |
免费 | 430篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 121篇 |
妇产科学 | 69篇 |
基础医学 | 86篇 |
口腔科学 | 15篇 |
临床医学 | 905篇 |
内科学 | 1139篇 |
皮肤病学 | 182篇 |
神经病学 | 405篇 |
特种医学 | 206篇 |
外科学 | 403篇 |
综合类 | 14篇 |
预防医学 | 115篇 |
眼科学 | 44篇 |
药学 | 36篇 |
1篇 | |
中国医学 | 6篇 |
肿瘤学 | 110篇 |
出版年
2023年 | 68篇 |
2021年 | 48篇 |
2020年 | 68篇 |
2019年 | 19篇 |
2018年 | 88篇 |
2017年 | 106篇 |
2016年 | 105篇 |
2015年 | 121篇 |
2014年 | 162篇 |
2013年 | 190篇 |
2012年 | 74篇 |
2011年 | 88篇 |
2010年 | 178篇 |
2009年 | 245篇 |
2008年 | 116篇 |
2007年 | 45篇 |
2006年 | 76篇 |
2005年 | 30篇 |
2004年 | 22篇 |
2003年 | 33篇 |
2002年 | 33篇 |
2001年 | 82篇 |
2000年 | 37篇 |
1999年 | 66篇 |
1998年 | 98篇 |
1997年 | 149篇 |
1996年 | 151篇 |
1995年 | 136篇 |
1994年 | 119篇 |
1993年 | 100篇 |
1992年 | 75篇 |
1991年 | 51篇 |
1990年 | 36篇 |
1989年 | 60篇 |
1988年 | 64篇 |
1987年 | 51篇 |
1986年 | 43篇 |
1985年 | 48篇 |
1984年 | 42篇 |
1983年 | 37篇 |
1982年 | 37篇 |
1981年 | 23篇 |
1980年 | 45篇 |
1979年 | 20篇 |
1978年 | 22篇 |
1975年 | 19篇 |
1973年 | 22篇 |
1960年 | 21篇 |
1955年 | 20篇 |
1954年 | 19篇 |
排序方式: 共有3868条查询结果,搜索用时 31 毫秒
1.
Femoral access‐related complications during percutaneous transcatheter aortic valve implantation comparing single versus double Prostar XL device closure 下载免费PDF全文
2.
HOCK LEONG EE MBBS MRCP CHEE LEOK GOH MBBS FRCP KHOO ES-Y. CHAN PHD POR ANG MBBS MRCP 《Dermatologic surgery》2006,32(1):34-40
BACKGROUND: Acquired bilateral nevus of Ota-like macules (Hori's nevus) is a common dyschromatosis among Asian women. Q-switched lasers have been used successfully as a treatment modality. OBJECTIVE: The purpose of this study was to compare the efficacy of using the Q-switched 532 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser followed by the 1,064 nm laser versus the Q-switched 1,064 nm Nd:YAG laser alone in the treatment of Hori's nevus. METHODS: This is a prospective left-right comparative study. Ten women with bilateral Hori's nevus were recruited and treated with a combination of the Q-switched 532 and 1,064 nm Nd:YAG lasers on the right cheek and the Q-switched 1,064 nm Nd:YAG laser alone on the left cheek. Only one laser treatment session was performed. The degree of pigmentation was objectively recorded with a mexameter. Subjective assessment was made by both patients and two blinded, nontreating dermatologists. RESULTS: At 6 months, there was a statistically significant difference (p = .009) of 35.10 points using objective mexameter measurements between the two sides, favoring the side treated with a combination of 532 and 1,064 nm laser treatment. Subjective grading by the patients and blinded dermatologists also confirmed that combination therapy was more successful after one treatment. Although combination treatment had a higher incidence of mild postinflammatory changes, this disappeared within 2 months. CONCLUSIONS: Concurrent use of the Q-switched 532 nm Nd:YAG laser in combination with the 1,064 nm laser is more effective in pigment clearance than the Q-switched 1,064 nm Nd:YAG laser alone for Hori's nevi. 相似文献
3.
Dr. Arthur A. Dunk MRCP Natasha Kyprianou MSc Peter Davies PhD Howard C. Thomas PhD FRCP 《Digestive diseases and sciences》1988,33(4):472-476
Castrated or sham-operated male athymic mice were inoculated with cells from the human hepatocellular carcinoma cell line PLC/PRF/5. There were no significant differences between the two groups with respect to the number of animals developing tumors, the time to tumor development, or the subsequent rate of increase in either tumor base area or mouse serum alpha-fetoprotein concentration. Androgen receptors were assayed in nuclei obtained from three separate liver cancer cell lines and from normal adult human liver. Similar concentrations, ranging from 235 to 550 fmol/mg DNA, of nuclear androgen receptors were detected in all tissues. Low percentages of androgen receptors were retained on DNA-cellulose. Although the presence of receptors implies the potential for metabolic effects of androgens in normal and malignant liver, our in vivostudies suggest that castration does not alter significantly the growth of liver cancer xenografts in athymic mice. 相似文献
4.
5.
M Vijaya Lakshmi MRCP G V Sridharan MRCP D Butterworth MRCP 《International journal of clinical practice》1993,47(3):164-165
Gallstones are common and their incidence increases with age.1 Fifty per cent of these stones are in the common bile duct (CBD) in the elderly.2 Most of them are silent but with time there is an increasing chance of developing symptoms which are more likely to be serious in the elderly.3 Failure to relieve mechanical obstruction of bile flow may lead to secondary biliary cirrhosis.4 It has been estimated that on average secondary biliary cirrhosis develops some seven years after the onset of obstruction from a stricture, four and half years after gallstone obstruction and 10 months after the onset of malignant stricture.5 The characteristic features are the pathological findings of portal-portal linkages, with a pattern of monolobular cirrhosis and the preservation of normal vascular relationships.6 Secondary biliary cirrhosis may lead to hepatic insufficiency and portal hypertension with the resultant complications, such as bleeding oesophageal varices, hypersplenism with pancytopenia, ascites and encephalopathy. We describe a patient in whom the diagnosis was not suspected until laparotomy and confirmed only at autopsy. 相似文献
6.
Over recent years the pharmacological treatment strategy for rheumatoid arthritis (RA) has changed. An early, aggressive approach has been adopted with a view to maintaining functional capacity. The changing role of nonsteroidal antiinflammatory agents is discussed in the light of the potential toxicity of this class of drugs. The current use of second-line agents is dealt with in depth and includes guidelines to patient monitoring. Particular attention has been paid to the growing use of cyclosporin A in the treatment of RA as this drug represents the newest, most potent, nonexperimental form of treatment. The questions of when to introduce second-line agents, who should receive treatment and how many drugs should be prescribed are all addressed in this review. The relative efficacy and toxicity of these agents is discussed and a treatment protocol is proposed. 相似文献
7.
Ketai LH; Williamson MR; Telepak RJ; Levy H; Koster FT; Nolte KB; Allen SE 《Radiology》1994,191(3):665
8.
AJ Larner MRCP 《International journal of clinical practice》1994,48(5):272-274
SUMMARY A case is reported of pseudohyperphosphataemia in association with a monoclonal gammopathy of undetermined significance. 相似文献
9.
10.
Tsungai Chipato MRCOG David L. Healy PhD FRACOG Beverley Vollenhoven MRACOG Helen M. Buckler MRCP 《The Australian & New Zealand journal of obstetrics & gynaecology》1991,31(4):383-384
We present these 3 cases to alert others to the possibility of severe pain with rapid shrinkage of fibroids occurring during LHRH analogue treatment. We suggest management of such events should not be surgical except for vaginal excision of prolapsed fibroid polyps. 相似文献