Pendular motion of the mediastinum

1. 1. Five types of mediastinal respiratory shift have been observed in twenty-one patients.

2. 2. In Types I and II the mediastinum is midline on expiration but is displaced to one side during inspiration. In Type II these findings are noted both on fluoroscopy and on x-ray; in Type I the shift is usually not seen on x-ray.

3. 3. In Type III the mediastinum is displaced to one side on expiration and to the opposite side during inspiration.

4. 4. In Type IV the mediastinum is midline on inspiration but is displaced toward the normal side on expiration.

5. 5. In Type V the mediastinum is pulled into the diseased side during both phases of respiration as a result of complete endobronchial occlusion.

     

青石棉诱导A549细胞ERK1/2、MEK1/2的表达

目的:了解细胞内信号传导在石棉致肺部疾患过程中的作用。方法:用Western免疫印迹法检测石棉刺激的A549细胞裂解液中MEK1/2、:ERK1/2的表达。结果:以0.1 g/L浓度的青石棉刺激A549细胞后,ERK1/2、MEK1/2磷酸化蛋白快速高表达,与空白对照比较,差异有统计学意义(P<0.05)。结论:磷酸化的信号蛋白可能在石棉致病中起重要作用。