<Emphasis Type="Italic">Susuks</Emphasis> (charm needles) in the craniofacial region

Objectives  We conducted a study to determine the numbers of susuks (charm needles) and their distribution in the craniofacial region of susuk wearers, and the sex, racial affiliation, and age of the wearers. In addition, we sought to determine whether the presence of susuks posed any potential hazard to patients undergoing magnetic resonance imaging (MRI). Methods  We studied various radiographs of 33 susuk wearers (age range, 33–69 years) and investigated the most common sites of insertion in the craniofacial region. A susuk was also suspended inside a 1.5-T MRI machine to determined whether it was attracted by the machine’s magnet. Results  The largest number of susuks that we observed in the craniofacial region was 39 pins, and susuks were particularly numerous in Malay Muslim women. Other sites with susuks were the maxillofacial region (except the temporomandibular region) and the forehead. The susuks showed no ferromagnetic characteristics. Conclusions  As susuks are made from gold, they are generally biocompatible with human tissue and do not cause problems to their wearers. Gold and the other minor metal constituents found in susuks have no ferromagnetic characteristics and therefore pose no hazard to patients undergoing MRI.     

Human papillomavirus detection: verification with cervical cytology.

OBJECTIVE: Thirteen specific types of human papillomavirus (HPV), classified as high-risk for the development of cervical cancer, have been reported in 99.7% of all cervical cancers. For this reason, and because of the reported lack of sensitivity of the Papanicolaou (Pap) smear for detecting HPV, some experts believe that the use of papillomavirus DNA testing may replace cytology for routine gynecological screening. Our goal was to validate a commercial assay, the Digene Hybrid Capture-2 for the detection of human papillomavirus by comparing the results to cytological detection of cervical abnormalities. DESIGN: Cytology results of concurrent liquid-based Papanicolaou smears were compared to the Hybrid Capture-2 results. Correlation was assessed and discordant cytology results were reviewed. SETTING: Louisiana State University Health Sciences Center at Shreveport, Department of Pathology, HPV Diagnostic Laboratory. PATIENTS: All liquid cytology specimens submitted for HPV testing between November 1, 2000 and April 1, 2001. RESULTS: Of the 291 cases tested by Hybrid Capture-2, 12% and 28% were positive with the low-risk and high-risk probes, respectively, and 265 had concurrent cytology results. Fourteen specimens testing positive only with the low-risk probe were not included in this comparison. Thus, the results for 251 of the 291 (86%) specimens tested for human papillomavirus DNA were compared to the original cytology report. Overall concordance between Hybrid Capture-2 and the original smear cytology result was 78%. Slide review reduced the number of discordant specimens from 22% to 12%. CONCLUSION: Based upon these data, we find the HPV assay to be useful as a routine screen for Human papillomavirus.     

Prevalence of proteinuria/microalbuminuria in an elderly urban, biethnic community

Introduction. The purpose of this study was to compare the prevalences of urinary abnormalities, notably proteinuria and microalbuminuria, in a randomly selected, biethnic population of Hispanic and nonHispanic white males and females and to determine the effects of diabetes, hypertension, and coronary heart disease on these prevalence rates. Methods. A survey of health and health related issues was conducted on 883 volunteers, mean age 74.1 years, selected randomly from the Medicare rolls of Bernallilo County (Albuquerque), New Mexico. The sample consisted of nearly equal numbers of Hispanic and nonHispanic white males and females. A dipstick urinalysis and test for microalbuminuria was performed on a clean void, untimed urine sample as a part of a 4-hour interview/examination. Results. Of the 696 participants with complete databases, 10.5% had 1+ or greater proteinuria (30 mg/dL or more) by convential urinalysis dipstick and 19.8% had microalbuminuria (50 mg/L or more) by Micral Chemstrip® methodology. Participants with diabetes mellitus (Odds Ratio (OR) 2.54, Confidence Interval (CI) 1.71–3.76, p < 0.001), and/or hypertension (OR 2.09, 95% CI 1.46–3.01, p < 0.001) were more likely to have microalbuminuria than participants without either of these conditions. After adjusting for the presence of diabetes and hypertension, there was a trend toward an increased prevalence of coronary heart disease (OR 1.23, 95% CI 0.84–1.81 p = 0.28) in those with microalbuminuria, but this did not reach levels of statistical significance. Conclusions. Hispanics, even after adjusting for a higher prevalence of diabetes, and for small differences in prevalences of hypertension and coronary heart disease, had more microalbuminuria than nonHispanic whites, and males had more microalbuminuria than females.     

Radiation‐induced angiosarcoma of the breast: A review

Angiosarcoma is a rare, aggressive malignant vascular neoplasm with poor prognosis that has a predilection for skin and superficial soft tissue. It can arise spontaneously or in association with factors like chronic lymphedema or radiation therapy. Radiotherapy used to treat invasive breast tumors is a known risk factor for the development of the so‐called radiation‐induced angiosarcoma (RIAS), a condition that has been described in the literature with increasing frequency. Radiation‐induced angiosarcoma of the breast usually arises on the previously irradiated skin area several years after radiotherapy and presents as painless multifocal erythematous patches or plaques similar to a hematoma. Cutaneous biopsy is essential for the diagnosis. Histologically, RIAS is characterized by irregular anastomosing vessels lined by endothelial cells showing nuclear atypia. Treatment is mostly surgical, and mastectomy with negative margins is considered the standard procedure. However, recurrences are common, and an approach combining surgery, chemo‐ and radiotherapy may be more effective. The purpose of this study is to review the most recent medical literature on RIAS of the breast, with emphasis on its pathophysiology, clinical and histological features and current treatment options.     

Falls among older adults seen at a São Paulo State public hospital: causes and consequences

OBJECTIVE: To investigate the history of accidental falls reported by older adults, identifying possibly related factors, as well as place of occurrence, causes, and consequences. METHODS: The sample investigated included 50 older adults, of both sexes, ages 60 years or older, living in the city of Ribeir?o Preto, Southeastern Brazil, who had been seen at two inpatient units of a public hospital. Patient records were examined and household visits carried out for the application of a structured questionnaire including open, closed, and mixed questions related to the fall. RESULTS: Data obtained show a reality not substantially different from that observed in other countries. Most events occurred among older women (66%), with mean age 76 years, and at home. Causes were mainly related to physical environment (54%), and brought serious consequences to the subjects, fractures being the most common outcome (64%). Falls had a great impact on subjects' lives in terms of activities such as: lying down/getting up, walking on plain surfaces, cutting toenails, bathing/showering, walking outside home, taking care of financial issues, shopping, using public transportation, and climbing stairs. CONCLUSIONS: The study demonstrated that falls occurred among older adults have serious physical, psychological, and social consequences, reinforcing the need for fall prevention, in order to ensure greater quality of life, autonomy, and independence for the elderly.     

Reliability and validity of uterine cancer death certificates in the municipality of Belém, Pará, Brazil

Belém, Pará State, Brazil, presents high mortality rates for uterine cervical cancer, thus justifying an analysis of the reliability and validity of data on this underlying cause of death. Death certificates for Belém residents who died in 1998-1999 from neoplasms of the uterine cervix, uterine body, or unspecified uterine site, or with mention of such a neoplasm on any line in the death certificate, were selected, amounting to 188 death certificates (DCs). All DCs were submitted to new coding, and reliability analysis was performed by simple agreement and Cohen's kappa. The underlying cause of death, established after review of medical records and/or histopathological findings, was considered the gold standard for analysis of criteria validity, based on the positive predictive value. We observed a simple agreement of 94.0% and kappa of 0.87, suggesting high reliability of the official system's coding of uterine cancer as the underlying cause of death. In the validity analysis, 120 of the 127 deaths originally considered as caused by cancer of the uterine cervix and 3 of the 4 coded as cancer of the uterine body were confirmed. An 11.2% increase in uterine cervical tumors and a reduction of 62.5% in unspecified uterine tumors were observed.     

Elderly persons with chronic kidney failure: health status alterations

This study aimed to describe health condition changes as experienced by elderly with Chronic Kidney Failure (CKF), under Continuous Ambulatory Peritoneal Dialysis (CAPD) treatment at the Dialysis and Kidney Transplantation Unit of a public hospital in Ribeir?o Preto -- SP, Brazil. Participants were six elderly under CAPD treatment, aged 61 to 74 years. The theoretical and methodological framework was thematic oral history as proposed by Meihy. Data analysis led to the category of changes in elderly's health condition and disclosed the diagnosis of the disease, signs and symptoms of CKF, causes and irreversibility.