全文获取类型
收费全文 | 156篇 |
免费 | 7篇 |
专业分类
儿科学 | 4篇 |
妇产科学 | 4篇 |
基础医学 | 16篇 |
口腔科学 | 2篇 |
临床医学 | 11篇 |
内科学 | 30篇 |
皮肤病学 | 10篇 |
神经病学 | 4篇 |
特种医学 | 20篇 |
外科学 | 24篇 |
综合类 | 5篇 |
预防医学 | 12篇 |
药学 | 20篇 |
肿瘤学 | 1篇 |
出版年
2023年 | 1篇 |
2022年 | 4篇 |
2021年 | 8篇 |
2020年 | 4篇 |
2019年 | 5篇 |
2018年 | 5篇 |
2017年 | 3篇 |
2015年 | 4篇 |
2014年 | 7篇 |
2013年 | 9篇 |
2012年 | 7篇 |
2011年 | 14篇 |
2010年 | 4篇 |
2009年 | 7篇 |
2008年 | 9篇 |
2007年 | 8篇 |
2006年 | 7篇 |
2005年 | 13篇 |
2004年 | 9篇 |
2003年 | 3篇 |
2002年 | 5篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1998年 | 3篇 |
1997年 | 1篇 |
1995年 | 1篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1986年 | 1篇 |
1980年 | 2篇 |
1979年 | 4篇 |
1977年 | 1篇 |
1975年 | 1篇 |
1974年 | 3篇 |
1971年 | 1篇 |
排序方式: 共有163条查询结果,搜索用时 31 毫秒
1.
We examined the possibility of establishment of patent infections after percutaneous exposure of parasite-naive pigs to 10,000
Oesophagostomum dentatum infective larvae (L3). At 5 weeks after percutaneous exposure the pigs were slaughtered and low numbers of adult O. dentatum were recovered from the large intestine. In addition, exsheathed L3 were intravenously injected into pigs, which resulted in the recovery of fourth-stage larvae (L4) from nodules in the lungs as well as of L4 and adult worms from the large intestine. This study demonstrates the ability of porcine nodular worms to establish in the
large intestine when pigs have been exposed percutaneously to infective larvae. It is possible that the larvae reach the large
intestine by invading blood veins or the lymphatic system at the site of penetration.
Received: 24 February 1998 / Accepted: 13 May 1998 相似文献
2.
Parasitic fauna of water frogs was mainly studied in the second half of the 20th century. However, these studies were done
without differentiation into species and hybrids and pooled the 3 taxa as “water frogs” or “green frogs”. The aim of this
study was to make an inventory of helminth species as well as their prevalence and intensity of infection in the two parental
species (Pelophylax ridibundus and P. lessonae) and the hybrid (P. esculentus) of water frogs from 3 big populations composed of hundreds or thousands of individuals inhabited natural and seminatural
landscapes in Poland. Eight helminth species were found: Polystoma integerrimum, Diplodiscus subclavatus, Opisthoglyphe ranae, Gorgodera cygnoides, Haematoloechus variegatus, Oswaldocruzia
filiformis, Cosmocerca ornata and Acanthocephalus ranae. The results were compared with data from other, polish and European studies. Additionally we compared the level of infection
among water frog taxa. 相似文献
3.
Diana Gassó Luca Rossi Gregorio Mentaberre Encarna Casas Roser Velarde Pawel Nosal Emmanuel Serrano Joaquim Segales Pedro Fernandez-Llario Carles Feliu 《Parasitology research》2014,113(9):3495-3500
Species of the Metastrongylus genus, the lung nematodes of pigs that require an intermediate host (earthworm) to complete their cycle, pose a potential risk to both livestock and humans. This parasite which can result in lung pathology and mixed infections with other pathogens (e.g. viruses) can be fatal to pigs. Although this genus is distributed worldwide, there are no classification keys for identifying this common parasite species. In this work, we take advantage of parasitological surveys of wild boar (Sus scrofa) in northern and central Spain and southern Poland to develop a morphological identification key for the five most common Metastrongylus species (Metastrongylus apri, Metastrongylus pudendotectus, Metastrongylus salmi, Metastrongylus confusus and Metastrongylus asymetricus). In addition, we provide the first record of M. confusus in Spain, probably unidentified until now due to the lack of appropriate identification keys. We hope that this user-friendly identification key will enable parasitologists and veterinary practitioners to avoid further misclassifications of Metastrongylus species. 相似文献
4.
Slominski RM Reiter RJ Schlabritz-Loutsevitch N Ostrom RS Slominski AT 《Molecular and cellular endocrinology》2012,351(2):152-166
Many of melatonin's actions are mediated through interaction with the G-protein coupled membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or, indirectly with nuclear orphan receptors from the RORα/RZR family. Melatonin also binds to the quinone reductase II enzyme, previously defined the MT3 receptor. Melatonin receptors are widely distributed in the body; herein we summarize their expression and actions in non-neural tissues. Several controversies still exist regarding, for example, whether melatonin binds the RORα/RZR family. Studies of the peripheral distribution of melatonin receptors are important since they are attractive targets for immunomodulation, regulation of endocrine, reproductive and cardiovascular functions, modulation of skin pigmentation, hair growth, cancerogenesis, and aging. Melatonin receptor agonists and antagonists have an exciting future since they could define multiple mechanisms by which melatonin modulates the complexity of such a wide variety of physiological and pathological processes. 相似文献
5.
6.
Rupa Seetharamaiah Rey Jesús Romero Radomir Kosanovic Michelle Gallas Juan-Carlos Verdeja Jorge Rabaza Anthony Michael Gonzalez 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2013,17(4):570-577
Background and Objectives:
Giant paraesophageal hernia accounts for 5% of all hiatal hernias, and it is commonly seen in elderly patients with comorbidities. Some series report complication rates up to 28%, recurrence rates between 10% and 25%, and a mortality rate close to 2%. Recently, the da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA, USA) has shown equivocal benefits when used for elective surgeries, whereas for complex procedures, the benefits appear to be clearer. The purpose of this study is to present our preliminary experience in robotic giant paraesophageal hernia repair.Methods:
We retrospectively collected data from patients who had a diagnosis of giant paraesophageal hernia and underwent a paraesophageal hernia repair with the da Vinci Surgical System.Results:
Nineteen patients (12 women [63.1%]) underwent surgery for giant paraesophageal hernia at our center. The mean age was 70.4 ± 13.9 years (range, 40–97 years). The mean American Society of Anesthesiologists score was 2.15. The mean surgical time and hospital length of stay were 184.5 ± 96.2 minutes (range, 96–395 minutes) and 4.3 days (range, 2–22 days), respectively. Nissen fundoplications were performed in 3 cases (15.7%), and 16 patients (84.2%) had mesh placed. Six patients (31.5%) presented with gastric volvulus, and 2 patients had other herniated viscera (colon and duodenum). There were 2 surgery-related complications (10.5%) (1 dysphagia that required dilatation and 1 pleural injury) and 1 conversion to open repair (partial gastric resection). No recurrences or deaths were observed in this series.Conclusion:
In our experience robotic giant paraesophageal hernia repair is not different from the laparoscopic approach in terms of complications and mortality rate, but it may be associated with lower recurrence rates. However, larger series with longer follow-up are necessary to further substantiate our results. 相似文献7.
Radomir D Stevanovic Naomi D L Fisher Cecilia M Lansang Katherine D Freeman Norman K Hollenberg 《Journal of the renin-angiotensin-aldosterone system》2007,8(2):85-92
Renin system blockade in diabetes exerts a strong positive influence on complications, especially nephropathy. In hyperglycaemic diabetic subjects, however, blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors results in a marked rise in plasma renin. We investigated whether glycaemic fluctuations measured in hours, or those measured in weeks by Haemoglobin A(1C) (HbA(1C)) , influenced the plasma renin response to captopril. Fifty-four type 1 diabetic subjects were studied in high-salt balance. After an all night fast and in the supine position, baseline serum glucose level was drawn. Iv. glucose and insulin were then administered to keep serum glucose between 100 and 150 mg/dL (target). When target was reached, captopril 25 mg pre os was administered and plasma renin activity (PRA) and finger stick glucose were drawn, then serially every 45 minutes for 225 minutes. Baseline glucose and baseline PRA were drawn hours apart. Peak PRA corresponded to the renin level at peak captopril effect, 90' after administration. Renin response (RR) = peak PRA - baseline PRA. Correlation of baseline glucose with baseline PRA was weak (r=0.3, p=0.02), but strong with peak PRA (r=0.65; p=0.002). Drop in glucose had a weak, negative correlation with baseline PRA (r=-0.3, p=0.03) but a much stronger one with peak PRA (r=-0.7, p<0.0001). After adjustment for baseline PRA and baseline glucose, mean RR correlated strongly with mean drop in glucose (r=-0.72; p=0.008). Conversely, HbA1C correlated with none of the measures of renin system activation (r=0.05;p=0.7). In type 1 diabetic subjects, short-term hyperglycaemia, but not long-term glycaemic control, enhanced the RR to captopril. 相似文献
8.
9.
Graczyk Radomir Chachaj Bogusław Stanek Magdalena Dąbrowski Janusz Gackowski Grzegorz 《Bulletin of environmental contamination and toxicology》2019,102(3):365-370
Bulletin of Environmental Contamination and Toxicology - The aim of this study was to examine fertility of spiny-cheek crayfish harvested in the first half of April from the Vistula Lagoon and to... 相似文献
10.