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Veldtman Gruschen Possner Mathias Mohty Dania Issa Ziyad Alsaleh Monerah AlMarzoog AlJuhara Thaar Emmanual Shisamma Salam Yezan AlHabdan Mohammed Saleh Alsaied Tarek Rathod Rahul H. Siblini Ghassan Vriz Olga 《The international journal of cardiovascular imaging》2021,37(9):2651-2660
The International Journal of Cardiovascular Imaging - Abnormal atrial mechanics in biventricular circulations have been associated with elevated left heart filling pressures. Similar associations... 相似文献
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Tobias A. Fuchs Julia Stehli Svetlana Dougoud Bert-Ram Sah Sacha Bull Olivier F. Clerc Mathias Possner Ronny R. Buechel Oliver Gaemperli Philipp A. Kaufmann 《The international journal of cardiovascular imaging》2014,30(7):1399-1405
To explore the feasibility of coronary artery calcium (CAC) measurement from low-dose contrast enhanced coronary CT angiography (CCTA) as this may obviate the need for an unenhanced CT scan. 52 patients underwent unenhanced cardiac CT and prospectively ECG triggered contrast enhanced CCTA (Discovery HD 750, GE Healthcare, Milwaukee, WI, USA). The latter was acquired in single-source dual-energy mode [gemstone spectral imaging (GSI)]. Virtual unenhanced images were generated from GSI CCTA by monochromatic image reconstruction of 70 keV allowing selective iodine material suppression. CAC scores from virtual unenhanced CT were compared to standard unenhanced CT including a linear regression model. After iodine subtraction from the contrast enhanced CCTA the attenuation in the ascending aorta decreased significantly from 359 ± 61 to 54 ± 8 HU (P < 0.001), the latter comparing well to the value of 64 ± 55 HU found in the standard unenhanced CT (P = ns) confirming successful iodine subtraction. After introducing linear regression formula the mean values for Agatston, Volume and Mass scores of virtual unenhanced CT were 187 ± 321, 72 ± 114 mm3, and 27 ± 46 mg/cm3, comparing well to the values from standard unenhanced CT (187 ± 309, 72 ± 110 mm3, and 27 ± 45 mg/cm3) yielding an excellent correlation (r = 0.96, r = 0.96, r = 0.92; P < 0.001). Mean estimated radiation dose revealed 0.83 ± 0.02 mSv from the unenhanced CT and 1.70 ± 0.53 mSv from the contrast enhanced CCTA. Single-source dual-energy scanning with GSI allows CAC quantification from low dose contrast enhanced CCTA by virtual iodine contrast subtraction. 相似文献
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Laurer HL Wutzler S Possner S Geiger EV El Saman A Marzi I Frank J 《Archives of orthopaedic and trauma surgery》2011,131(7):983-989
Introduction
The rate of periprosthetic femoral fractures after hip arthroplasty is rising and the estimated current lifetime incidence is 0.4–2.1%. While most authors recommend revision arthroplasty in patients with loose femoral shaft components, treatment options for patients with stable stem are not fully elucidated. 相似文献9.
Julia Stehli Tobias A. Fuchs Sacha Bull Olivier F. Clerc Mathias Possner Ronny R. Buechel Oliver Gaemperli Philipp A. Kaufmann 《Journal of the American College of Cardiology》2014
Background
Coronary computed tomography angiography (CTA) is increasingly being used for evaluation of coronary artery disease (CAD). As a result of the widely reported potential of carcinogenic risk from x-ray based examinations, many strategies have been developed for dose reduction with CTA.Objectives
The purpose of this study was to assess the diagnostic accuracy of CTA acquired with a submillisievert fraction of effective radiation dose reconstructed with a model-based iterative reconstruction (MBIR) using invasive coronary angiography (ICA) as a standard of reference.Methods
In 36 patients (body mass index range 17 to 39 kg/m2) undergoing ICA for CAD evaluation, a CTA was acquired using very low tube voltage (80 to 100 kV) and current (150 to 210 mA) and was reconstructed with MBIR. CAD (defined as ≥50% luminal narrowing) was assessed on CTA and on ICA.Results
CTA resulted in an estimated radiation dose exposure of 0.29 ± 0.12 mSv (range 0.16 to 0.53 mSv), yielding 96.9% (436 of 450) interpretable segments. On an intention-to-diagnose basis, no segment was excluded, and vessels with at least 1 nonevaluable segment and no further finding were classified as false positive. This resulted in a sensitivity, specificity, positive, and negative predictive value and accuracy of 100%, 74%, 77%, 100%, and 86% per patient and 85%, 86%, 56%, 96%, and 85% per vessel, respectively.Conclusions
The use of MBIR reconstruction allows accurate noninvasive diagnosis of CAD with CTA at a submillisievert fraction of effective radiation dose comparable with a chest x-ray in 2 views. 相似文献10.
Adam Possner MD 《Journal of general internal medicine》2013,28(9):1249-1249